Báo cáo y học: "The AID/APOBEC family of nucleic acid mutators" pot

... several very different areas of future research in reproductive biology, evolutionary biology, gene therapy and nanotechnology. An increasing number of biochemical studies of sperm produced by infertile ... formation of a network of disulfide bonds. The inactivation of the majority of the spermatid’s genes paves the way for the reprogram- ming of the male genome and the initia...

Ngày tải lên: 14/08/2014, 08:20

... Characterization of the murine B7.2 gene and identification of differen- tially spliced forms. 7. Guo Y, Wu Y, Zhao M, Kong XP, Liu Y: Mutational analysis and an alternatively spliced product of B7 defines ... spatial control of immune responses. Similar costimulatory and coinhibitory para- digms apply to other members of the B7 family, as outlined in Table 1, although details...

Ngày tải lên: 14/08/2014, 14:21

... tteekkttiinn ggeenneess iinn ddiiccyyeemmiidd mmeessoozzooaannss ((PPhhyylluumm:: DDiiccyyeemmiiddaa)) J Parasitol 2007, 9933:: 608-618. 24. Arenas-Mena C, Wong KS -Y, Arandi-Forosani N: CCiilliiaarryy bbaanndd ggeennee eexxpprreessssiioonn ... disassembly [64]? As tektins are unlikely to be reused [59,60], they might be phosphorylated immediately after translation, dephosphorylated in the...

Ngày tải lên: 14/08/2014, 20:22

... Zhang Y, Hegen M, Xu J, et al: Characterization of [2R, 3S]-2-[[[4-[2-butynyloxy]phenyl]sulfonyl]amino]-N,3- dihydroxybutanamide, a potent and selective inhibitor of TNF-alpha converting enzyme. ... progres s to a symptomatic stage. However, a minority are aggressive and rapidly progress causing morbidity and mortal- ity. A major everyday problem in the management of men with newly dia...

Ngày tải lên: 13/08/2014, 13:20

... homology with any of the MAP1 family members; phylogenetic relationships of the two families were therefore analyzed separately using Phylip [60]. Drosophila Futsch and the family members found by ... stabilization specifically by reducing depolymerization rates [25]. Phosphorylation of MAP1B by glycogen synthase kinase-3 ␤ (GSK3␤) has been extensively studied both in vitro and in v...

Ngày tải lên: 14/08/2014, 16:21

... ooff tthhee AAIIDD//AAPPOOBBEECC ffaammiillyy ooff ppoollyynnuucclleeoottiiddee ((ddeeooxxyy))ccyyttiiddiinnee ddeeaammiinnaasseess pprreeddiicctteedd bbyy ccoommppuuttaattiioonnaall aannaallyyssiiss ... Petersen-Mahrt SK, Neuberger MS: EEvvoo lluuttiioonn ooff tthhee AAIIDD//AAPPOOBBEECC ffaammiillyy ooff ppoollyynnuucclleeoottiiddee ((ddeeooxxyy))ccyyttiiddiinnee ddeeaammiinnaasseess Mol...

Ngày tải lên: 14/08/2014, 08:21

... that, in the majority of patients, premonitory signs and symptoms of cardio- pulmonary instability are often present hours before clinical deterioration [6]. By encouraging early responses to patients with ... patient and a weekly 1-hour Commentary The evolving story of medical emergency teams in quality improvement André Carlos Kajdacsy-Balla Amaral 1 and Kaveh G Shojania 2 1 Departme...

Ngày tải lên: 25/10/2012, 10:06

... University, Faculty of Medicine, Izmir, TURKEY. 2. Clinic of Plastic Reconstructive and Aesthetic Surgery, Public Hospital, Mus, Turkey. 3. Clinic of Plastic Reconstructive and Aesthetic Surgery, ... group, 56.9±14 years versus 30.3±6 years, respectively. It can be commented that, head and neck tumors are mostly seen in elderly patients whereas younger peo- ple may have high rates...

Ngày tải lên: 25/10/2012, 11:00

... chemical synthesized [13, 14]. The most commonly used is known as T-1095 (3-(benzofuran-5-yl)-2',6'-dihydroxy-4'-methylpropio- phenone 2'-O-(6-O-methoxycarbonyl-β-D-glyco- pyranoside) ... Med. Sci. 2007, 4 137 tory effect of thioglycoside I (phenyl-1’-thio-β-D glucopyranoside) on hSGLT2 and thioglycoside VII (2-hydroxymethyl-phenyl-1’-thio-β-D-galactopyranosi de)...

Ngày tải lên: 26/10/2012, 10:04

... by enzyme immunoassay, becomes positive near the onset of symptoms, approximately 1 to 3 months after exposure. Up to 30% of patients will test negative for anti-HCV at onset of their symptoms, ... antibodies.[20] In the Dionysos study from Italy, residents between the ages of 12 and 25 years had a chronicity rate of 56%, compared with 87% for those above the age of 25 yea...

Ngày tải lên: 02/11/2012, 09:56