Báo cáo y học: " Does a new polyomavirus contribute to Merkel cell carcinoma" pot

Báo cáo y học: " Does a new polyomavirus contribute to Merkel cell carcinoma" pot

Báo cáo y học: " Does a new polyomavirus contribute to Merkel cell carcinoma" pot

... double-stranded DNA genome of approximately 5 kb. It has been well established that many polyomaviruses are able to transform mammalian cells [14]. The best- characterized polyomavirus, SV40, was originally ... animal cancers. Polyomavirus family members are known to have two other T antigen proteins with transforming ability. MCPyV is predicted to express a small T antigen that is...
Ngày tải lên : 14/08/2014, 08:21
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Báo cáo y học: " Does a positive anti-CCP test identify a distinct arthritis entity" docx

Báo cáo y học: " Does a positive anti-CCP test identify a distinct arthritis entity" docx

... late. Conclusions The ACPA era has just begun, but has already proved to be a revolution in rheumatology. Although a positive anti-CCP test does not appear to identify patients with distinct clinical characteristics ... RA also vary depending on the choice of analytical method and on the study population. At a diagnostic sensitivity equal to agglutinating RF, the second- generat...
Ngày tải lên : 09/08/2014, 07:20
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Báo cáo y học: "SAMHD1: a new insight into HIV-1 restriction in myeloid cells" ppt

Báo cáo y học: "SAMHD1: a new insight into HIV-1 restriction in myeloid cells" ppt

... otherwise activate type I IFN expression and trigger an innate immune response [15]. Interestingly, similar to SAMHD1, TREX1 mutations in humans are associated with autoimmune and inflammatory diseases, ... HIV-1 Vpr does not interact or degrade SAMHD1 [10]. SAM domains are putative protein inter- action modules that are capable of self-association and binding to RNA and non-SAM domain...
Ngày tải lên : 13/08/2014, 01:21
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Báo cáo y học: "iBsu1103: a new genome-scale metabolic model of Bacillus subtilis based on SEED annotations." pdf

Báo cáo y học: "iBsu1103: a new genome-scale metabolic model of Bacillus subtilis based on SEED annotations." pdf

... K, Tohata M, Sawada K, Liu S, Ozawa T, Kodama T, Kakeshita H, Kageyama Y, Manabe K, Kanaya S, Ara K, Ozaki K, Ogasawara N: Enhanced recombinant protein produc- tivity by genome reduction in Bacillus ... the Additional data files, including metabolite structures (Additional data file 3), metabolite data (Table S1 in Additional data files 1 and 2), reaction data (Table S2 in Additional data fi...
Ngày tải lên : 14/08/2014, 21:20
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Báo cáo y học: "Relating a calcium indicator signal to the unperturbed calcium concentration time-course" potx

Báo cáo y học: "Relating a calcium indicator signal to the unperturbed calcium concentration time-course" potx

... we make a new measurement of y new (t). Use this to create a new D-dimensional data vector U new (t) = [y new (t), y new (t - τ ), y new (t - 2 τ ), , y new (t - (D - 1) τ )]. Search among all ... Henry DI Abarbanel 2 Address: 1 Max-Planck-Institute of Neurobiology, Martinsried, Germany and 2 Department of Physics and Marine Physical Laboratory (Scripps Inst...
Ngày tải lên : 13/08/2014, 16:21
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Báo cáo y học: "Does anesthetic provide similar neuroprotection to therapeutic hypothermia after cardiac arrest?" pot

Báo cáo y học: "Does anesthetic provide similar neuroprotection to therapeutic hypothermia after cardiac arrest?" pot

... from cardiac arrest remains a critical challenge.  erapeutic hypothermia, introduced more than six decades ago, remains an impor tant neuroprotective factor in cardiac arrest. Laboratory studies ... Meybohm and colleagues [1] demon- strate that cardiac arrest triggers the release of cerebral infl ammatory cytokines in pigs’ cerebral cortex.  era- peutic hypothermia alters infl ammatory...
Ngày tải lên : 13/08/2014, 20:21
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Báo cáo y học: "BoCaTFBS: a boosted cascade learner to refine the binding sites suggested by ChIP-chip experiments" pot

Báo cáo y học: "BoCaTFBS: a boosted cascade learner to refine the binding sites suggested by ChIP-chip experiments" pot

... relevant to the rules here. The overall sum of all the nodes is +0.803, a confident score indicating that this is predicted to be a binding site. AACAGGAATA ATCAAGACAT TTCACGAATG …… …… ACGTCGATAC Binding ... straightforward static sampling over such a large dataset may result in a significant loss of infor- mation and a potentially biased classifier. A standard boost- ing alg...
Ngày tải lên : 14/08/2014, 17:22
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Báo cáo y học: "Reactome: a knowledge base of biologic pathways and processes" pot

Báo cáo y học: "Reactome: a knowledge base of biologic pathways and processes" pot

... soft- ware implements a Bayesian algorithm that takes pathway topology information into account. Reactome, in contrast, uses a less sophisticated approach that takes the human path- way topology as ... groups to download the Reac- tome database and software, install it locally, set up their own large or small-scale curatorial effort, and contribute curated pathways back to the main...
Ngày tải lên : 14/08/2014, 20:22
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Báo cáo y học: " DISTILLER: a data integration framework to reveal condition dependency of complex regulons in" ppsx

Báo cáo y học: " DISTILLER: a data integration framework to reveal condition dependency of complex regulons in" ppsx

... framework DISTILLER to a combination of publicly available microarray data and regulatory motif data. This allowed us to considera- bly extend the transcriptional network with novel interac- tions for regulators ... 7:R37. 20. Tanay A, Sharan R, Kupiec M, Shamir R: Revealing modularity and organization in the yeast molecular network by integrated analysis of highly heterogeneous genome...
Ngày tải lên : 14/08/2014, 21:20
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Báo cáo khoa học: "Adapting a WSJ-Trained Parser to Grammatically Noisy Text" pot

Báo cáo khoa học: "Adapting a WSJ-Trained Parser to Grammatically Noisy Text" pot

... parsers to accurately handle ungrammatical text is an instance of the do- main adaptation problem where the target domain is grammatically noisy data. A parser can be adapted to a target domain ... re- sembles material from the noisy target domain. In order to tune a parser to syntactically ill-formed text, a treebank is automatically transformed into an ungrammatical treebank...
Ngày tải lên : 17/03/2014, 02:20
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