Báo cáo y học: " A computational model of gene expression reveals early transcriptional events at the subtelomeric regions of the malaria parasite, Plasmodium falciparum" docx

... Issue 5, Article R88 Research A computational model of gene expression reveals early transcriptional events at the subtelomeric regions of the malaria parasite, Plasmodium falciparum Matthias Scholz ... identify genes that involve a circular component in data space. To model the infection cycle and obtain the rate of change for each gene at...

Ngày tải lên: 14/08/2014, 08:21

... investigate the statistical properties of the model. Model Mathematical Modeling of Circadian Rhythms In all organisms studied so far, circadian rhythms that allow adaptation to a periodically changing ... number of variables. For this reason, mathematical models and numerical simulations are needed to grasp the molecular mechanisms and functions of biological rhythms fully...

Ngày tải lên: 13/08/2014, 16:21

... (partially) shared by some of the other seven re- searchers. Comparison with Other Hypotheses Another way of evaluating the output of B and J is to compare them with the hypotheses of other researchers. ... for ancient literary texts, with novel features that account for source alternation patterns. These features were val- idated on the Lukan Passion Narrative, an instance o...

Ngày tải lên: 08/03/2014, 02:21

... background information it could take advantage of. The reason is that too many queries makes the pro- gram loses its appeal as a work-saving device. A related limitation is that its model of ... forming a detailed user profile and applying across a large set of generated letters. The other important limitation is that its organizational and text templates are not pa...

Ngày tải lên: 08/03/2014, 05:21

... verbal - adverbial waratte (laugh-and), amaku (sweetly) verbal - adnominal warau (that laughs), amakatta (that was sweet) The bunsetsu generally behaves as a prosodic unit. Although the syntactic ... Haraguchi, Shosuke (1977) The Tone Pattern of Japanese: An Autosegmental Theory of Tonology. Kaitakusha, Tokyo. Kaplan, Ronald and Joan Bresnan (1982) Lexical Functional Gr...

Ngày tải lên: 09/03/2014, 01:20

... Matlab R14 (Nat- ick, MA) and Statistica v7 (Tulsa, OK, USA). An alpha level of 0.05 was considered statistically significant for all anal- yses. Analysis of the apoptosis assays was undertaken ... or pathophysiologic function. For that reason, we elected to test the validity of the array data by examining a physiologic mechanism implicated by computer modelling of the array...

Ngày tải lên: 11/08/2014, 08:21

... investigation, there were no suitable European datasets available against which the model could be fully externally validated. Therefore, to gain a measure of the applicability of the model to other ... utility of the FLIP 7-variable model was highlighted by an examination of NNT. Assuming a 5% hospitalisation rate and 80% treatment efficacy, the calcu- lated NNT t...

Ngày tải lên: 12/08/2014, 14:20

... suffi- ciently precise to allow inclusion in a mathematical sense, the analysis clearly indicated that inclusion of contact intensity would amplify the observed phenomena rather than falsify our conclusions. Finally, ... every time category, we defined a precise value (the arithmetic mean of the upper and lower boundaries) that was used for all calculations. However, a sensit...

Ngày tải lên: 13/08/2014, 16:20

... treatment of a spatially structured Pseudomonas aeruginosa population. Journal of Mathematical Biology 2005, 51:557-594. 40. Anguige K, King JR, Ward JP: A multi-phase mathematical model of quorum ... T, Nakamura Y, Yamazaki G, Ishida A, Kato N, Ikeda T: The Plant Pathogen Pantoea ananatis Produces N- Acylhomoserine Lactone and Causes Center Rot Disease of Onion by Quorum Se...

Ngày tải lên: 13/08/2014, 16:20

... complications that require further treatment or surgery [1,2]. The data analy- sis of the Dialysis Outcomes Quality Initiative panel [2,3] suggests a primary patency of 85% for AV fistulas at one year ... at one year and 75% at two years, whereas the ePTFE graft pat- ency can be as low as 50% after one year and 20% at two years. These data exclude fistulae that did not mat...

Ngày tải lên: 13/08/2014, 16:21