Báo cáo y học: " Individual mRNA expression profiles reveal the effects of specific microRNAs Amit Arora and David AC Simpson" pot

... between the medians of the ranked gene expression values of the two sets, the nonparametric one-sided Wilcoxon rank sum test was employed. To test the hypothesis that the genes in each set are from the ... predict many of the previously char- acterized, highly expressed and/ or tissue -specific miRNAs (for example, 14 of 25 in brain). This approach will facilitate...

Ngày tải lên: 14/08/2014, 08:21

... the examination of the women. We, further, would like to acknowledge R Dolgner and M Islam for co-ordinating the study and the spirometry. The Ministry of the Environment of NRW financed the ... function by using FEV 1 < 80% and FVC < 80% of the predicted value of each parameter. These cut-offs were also used in the re-analysis of the Har- vard...

Ngày tải lên: 12/08/2014, 15:20

... and Dacheng Ren 1,2,4,5* 1 Department of Biomedical and Chemical Engineering, Syracuse University, Syracuse, NY 13244, USA 2 Syracuse Biomaterials Institute, Syracuse University, Syracuse, ... by DC is not through direct physical forces of the currents (no change in the integrity of cells), but the electrochemical factors may play important roles. The effects of...

Ngày tải lên: 20/06/2014, 23:20

... at a given dose, but the approach is general and may be applied to any other expression of survival. To test the applicability of the approach, the model was fitted to a range of clonogenic survival ... contributions AC participated in the design of the study, executed the laboratory experiments and drafted the manuscript. SB participated in the design of...

Ngày tải lên: 13/08/2014, 16:21

... profile of MMPs and TIMPs involved may vary between these models. This study adopted the novel approach of elucidating the expression profile of a range of MMPs and TIMPs with the use of assays ... implicating the involvement of these pro- teases in the pathogenesis of inflammatory diseases, many of these reports only focus on the role of one particular MMP...

Ngày tải lên: 12/08/2014, 14:20

... the implication of the activation of MAP kinase in LPS- induced iNOS and COX-2 expression [28-30] and the acti- vation of NF-κB [30-33]. To demonstrate other pathway of NF-κB inactivation by melittin and ... reduced in the LPS treated synoviocytes, and SNP treated Raw 264.7 cells and synoviocytes, but the expression ERK and p38 was also reduced, indicating th...

Ngày tải lên: 11/08/2014, 08:22

... purposes) Illustrations of the top gene networks at the 3 day time point of the time-dependent microarray analysisFigure 4 Illustrations of the top gene networks at the 3 day time point of the time-dependent ... euthanasia. Immunohistochemistry The mice were anesthetized as above at 3 days and 7 days after surgery (PNY or SHAM) then euthanized by cervical dislocation....

Ngày tải lên: 12/08/2014, 14:20

... analyzed, unblinding revealed that 31 of the mothers had no maternal history of atopy, and 19 mothers had maternal atopy. Of these 19, 2 mothers had a doctor's diagnosis of asthma, 2 of them ... C, Bhattacharya A, Anklam K, Gilbertson-White S, Hamilton R, et al.: Developmental cytokine response profiles and the clinical and immunologic expression of atopy during...

Ngày tải lên: 12/08/2014, 16:20

... approximately 10 %. Interestingly, the majority of the cases had no symptoms at all and only in 2 cases the spacer had to be exchanged in an additional surgery. For prevention of a spacer fracture, the ... Spacer fractures could be noticed in 9 cases (10.2 %). 7 of them were localized in the distal part of the spacer stem and were asymptomatic. The other two...

Ngày tải lên: 26/10/2012, 09:53

... trichloroacetic acid to a final concentration of 5% to precipitate the protein. After removal of the protein by centrifugation, the trichloroacetic acid was removed by extraction with diethyl ether, and ... microlitre of the matrix solution and 1 lLof the peracetylated oligosaccharides in chloroform were mixed on the sample plate directly and dried to avoid Fig. 1. Sepa...

Ngày tải lên: 22/02/2014, 07:20