Báo cáo y học: "bEstrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly" docx
Báo cáo y học: "bEstrogen, not intrinsic aging, is the major regulator of delayed human wound healing in the elderly" docx
... novel insight into the relative contribution of hormones and intrinsic aging, including gerontogenes, to delayed wound healing. There exists a substantial body of research addressing the tis- sue, ... [16]. In concordance with the pro-inflammatory aging state, not only is 'inflammatory response' the major GO group overrep- resented in the list of...
Ngày tải lên: 14/08/2014, 08:21
Báo cáo y học: "Excess circulating angiopoietin-2 is a strong predictor of mortality in critically ill medical patients"
... the growing body of evidence indicating a role for Ang-2 as a mediator in critically illness, the value of Ang-2 as a predictive marker of outcome is poorly defined. The aim of this study was to investigate ... our patients. This finding is in apparent contrast to normal admis- sion levels of Ang-1 in the aforementioned studies [22,23]. We assume that a decline in...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" potx
... immunity is regulated by highly sophisticated cytokine networks. Comprehending the patho- logical roles of these abnormally induced cytokines and immu- noregulatory networks of cytokines in SLE ... scan- ning of the microarrays. YA assisted with data analysis. NY-H assisted with data analysis. KM assisted in microarray data acquirement. NN designed the study, enrolled patien...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "Natural killer cell dysfunction is a distinguishing feature of systemic onset juvenile rheumatoid arthritis and macrophage activation syndrome" pot
... joints involved), polyarticular (five or more joints), and systemic. The systemic onset form, with its markedly febrile presentation, is certainly the most distinct clinical subtype of the disease. ... patterns indis- tinguishable from those seen in healthy controls, suggest- ing that the observed NK dysfunction is not likely to be related to abnormal granzyme B expression....
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Ultrasonography, magnetic resonance imaging, radiography, and clinical assessment of inflammatory and destructive changes in fingers and toes of patients with psoriatic arthritis" pot
... more synovitis in the MCP and PIP joints in RA patients. A high frequency of synovitis was registered in MTP joints, including in CTRLs. The frequency of tenosynovitis was generally higher in RA ... tool increasingly used by clinicians, including rheumatologists, but the US data on small joints in PsA are very limited [8,9]; in particular, the validation of the f...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: " Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" pptx
... analysis, interpreta- tion of the microarray studies, and patient recruitment. HS assisted with data analysis. CA performed labeling and scan- ning of the microarrays. YA assisted with data analysis. ... E2 is a versatile hormone that plays a wide variety of roles in our body [36]. We therefore cannot exclude the pos- sibility that E2 also plays a significant role in the p...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: " FISH Oracle: a web server for flexible visualization of DNA copy number data in a genomic contex" ppsx
... gene annotations which are not handled by arrayCGHbase. On the other hand, arrayCGHbase allows the display of raw intensity values which is not displayed by FISH Oracle. Considering the use of both ... select groups of segments to be visualized. We expect that the high quality of the visualization and the flexibility ofthesoftwarewillenablelifescientiststoquickly der...
Ngày tải lên: 10/08/2014, 09:22
Báo cáo y học: "Rural-urban migration patterns and mental health diagnoses of adolescents and young adults in British Columbia, Canada: a case-control study" ppsx
... time of diagnosis of the case. Given this procedure, it is possible that a participant is a control in the analysis pertaining to a specific diagnosis, but a case in the analysis pertaining to another ... significantly impact mental health outcomes is the individual history of migration from one place to another, especially when the place of origin differs signific...
Ngày tải lên: 13/08/2014, 18:21
Báo cáo y học: "Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status" pps
... protein expression in tumors [35]. As a result, and to further examine the validity of the results of the bioinformatic analysis of the present study, we have recently undertaken a meta-analysis of ... be the critical step in tumorigenesis in epidermis and epithelia [76]. Interestingly, the involve- ment of RELA and NF κ B1 in the Wnt/ β -catenin pathway was n...
Ngày tải lên: 14/08/2014, 08:20
Báo cáo khoa học: Ets-1/ Elk-1 is a critical mediator of dipeptidyl-peptidase III transcription in human glioblastoma cells pdf
... visualized by electropho- retic mobility shift and chromatin immunoprecipitation assays. Mutations of these binding sites abolished not only binding of the Ets protein, but also the intrinsic promoter ... blotting using an antibody raised against the phosphorylated form of Erk-1 or a-tubulin protein. (E) Densitometric quantitation of the phosphorylated form of Erk-1. Th...
Ngày tải lên: 29/03/2014, 09:20