Báo cáo y học: "RNA polymerase II stalling: loading at the start prepares genes for a sprint" pot

... 2005, 33:: e76. 3. Aida M, Chen Y, Nakajima K, Yamaguchi Y, Wada T, Handa H: TTrraann ssccrriippttiioonnaall ppaauussiinngg ccaauusseedd bbyy NNEELLFF ppllaayyss aa dduuaall rroollee iinn rreegguullaattiinngg iimmmmeeddiiaattee ... HHoolldd bbaacckk ooff RRNNAA ppoollyymmeerraassee IIII aatt tthhee ttrraannssccrriipp ttiioonn ssttaarrtt ssiittee mmeeddiiaatteess ddoowwnn rreegguullaatt...

Ngày tải lên: 14/08/2014, 08:21

... of polymerases rather than the more evenly spaced polymerases seen at growth/housekeeping genes [24], and it has recently been shown that a trailing polymerase can aid the lead- ing polymerase ... (b) Data from (a) , but plotted as a graph rather than a heatmap. Data on the y- axis are shown as log(2). Probes annotated as 5’, mid, and 3’ CDS are indicated below the gene...

Ngày tải lên: 09/08/2014, 20:22

... 1). Alterna- tively, a partial (Figure 2) or normal cementation of the spacer into the femoral canal provides the advan- tage of rotational and axial stability [3]. A normal ce- mentation has the ... be performed that guarantees an infection eradication and has a minimal risk regarding the abovementioned mechanical complications. In the past 10 years approximately 100 pat...

Ngày tải lên: 26/10/2012, 09:53

... http://www.annals-general-psychiatry.com/content/4/1/6 Page 3 of 8 (page number not for citation purposes) The translation and the cultural adaptation of the Royal Free Interview for Spiritual and Religious Beliefs was car- ried out at an early ... spirituality index of well-being: a new instrument for health-related Quality-of-Life research. Annals of Family Medicine 2004, 2(...

Ngày tải lên: 08/08/2014, 21:20

... hyperprolactinaemia, or weight gain. However, EPS such as akathisia was more fre- quently reported in aripiprazole-treated than in placebo- treated patients, but at a rate of approximately half ... electrocardiogram (ECG). The above studies strongly support the efficacy of aripipra- zole against acute mania and they report that the separa- tion from placebo occurred as early as days...

Ngày tải lên: 08/08/2014, 23:21

... thus excluding the possibility that the lack of therapeutic activity was due to the inability of CD4 + CD25 + Treg to migrate into the inflamed tissue. The authors also pointed out that a ‘true’ curative activity ... Research & Therapy. There are, however, key questions that have not yet been addressed before their use can be considered as a real therapeutic option. The fi...

Ngày tải lên: 09/08/2014, 06:23

... more than a decade, with the discovery of many critical genes and the characterization of the mutational sp ectra of these genes as they were identified (for example, [5,7,28,29]). Therefore, the ... 3). Proband Z43 8A, of Algerian origin, was homozygous for the mutation, which segregated with hearing loss in his family. Another deaf proband with partial Algerian ancestry,...

Ngày tải lên: 09/08/2014, 23:20

... carried out the T-cell isolation, T-cell proliferation, cytokine analysis and MLR and analysis of the data. IE participated in the T-cell proliferation assays and statistical analysis. MB participated ... disease. Acknowledgements We are very grateful to Dr. Beth A. Garvy and Yajarayma Tang-Feldman for their critical review of the manuscript and helpful discussions. This work was s...

Ngày tải lên: 11/08/2014, 06:22

... patient completely recovered, was asymptomatic and had a nor- mal bladder. A follow-up 3 years later revealed an asymp- tomatic patient and ultrasonic inspection and cystoscopy showed no evidence of disease ... contributions YL and DX managed the patient and reviewed the litera- ture. YG and JR were the main writers of the manuscript. CM, XZ and CQ moderated the manuscript. All...

Ngày tải lên: 11/08/2014, 17:21

... showed dedifferentiation with sarcomatoid features probably representing a highly virulent phenotype. Abbreviations AE1/AE3, cytokeratin AE1/AE3; CAM5.2, cytokeratin CAM5.2; CEA, carcinoembryonic antigen; ... with the latter being an adenosqua- mous carcinoma. Like our patient, in the case reported by Albores-Saavedra et al., there was also focal cytokeratin positivity to CAM5.2 of the...

Ngày tải lên: 11/08/2014, 17:21