Báo cáo y học: "A pathway sensor for genome-wide screens of intracellular proteolytic cleavage" ppt

... Although autophagy is currently widely investigated, the systematic identification of molecular events in autophagy has been hampered by the lack of suitable assays. Current assays to study autophagy measure ... (Sigma). Genome Biology 2008, 9:R64 Open Access 2008Ketteleret al.Volume 9, Issue 4, Article R64 Method A pathway sensor for genome-wide screens of intracellular pr...

Ngày tải lên: 14/08/2014, 08:21

... regulated not only by inflammatory cytokines but also by the physical interaction of activated leukocytes with fibroblast-like synoviocytes, and that IP-10 may contribute to the recruitment of specific ... reg- ulated not only by inflammatory cytokines but also by the physical interaction of activated leukocytes with FLSs. Once expressed, IP-10 probably plays a crucial role in the migra...

Ngày tải lên: 09/08/2014, 01:21

... details 1 Max von Pettenkofer-Institute, Virology, Munich, Germany. 2 Mikrogen GmbH, Neuried, Germany. 3 Protagen AG, Dortmund, Germany. 4 University of Edinburgh, Division of Pathway Medicine, Edinburgh, ... recombinant VZV antigens . B) Frequency of IgM reactivity of clinically defined samples and serologically defined VZV-IgG/IgM negative samples, (*) as assayed by Enzygnostic wc...

Ngày tải lên: 12/08/2014, 04:20

... standards accounted for approximately 20% of the total mass of PHY906, 38% of the total mass of phytochemicals after correction for excipient and residual water content and 58% of the total mass of phytochemicals ... were used for batch-to-batch comparisons. Of the 39 peaks of the chemical fingerprint of PHY906 (S) accounted for 25 of 39 peaks, (P) accounted for...

Ngày tải lên: 13/08/2014, 15:21

... orthogonality of the DNA genetic information Biological systems also rely upon the property of orthogonality of info rmation in order to minimize the chance of improper interpretation of the genetic ... i.e. for the subsequent use of the information. It represents the necessary step for the utili- zation of stored inform ation by the overall system. In a computer, this funct...

Ngày tải lên: 13/08/2014, 16:20

... rhythm, circadian activity level, and dissociation of rhythmicity. The data of Shimomura et al. [24] point to promising approaches for genome-wide analysis of rhythmic pheno- types in mammals including ... matrix (Σ) of phenotypic values for traits y and z can be structured in terms of φ y , φ z , ψ y , ψ z and Σ ε (t) by a bivariate SAD(1) model [15,16]. Also, the...

Ngày tải lên: 13/08/2014, 16:21

... of 9 (page number not for citation purposes) The LR is asymptotically χ 2 -distributed with one degree of freedom. A similar test for the existence of a QTL can be performed on the basis of ... Chen YM, Wu RL: A unifying differential equation model for functional genetic mapping of circadian rhythms. Theor Biol Medical Modeling 2007, 4:5. 24. Lynch M, Walsh B: Genetics and...

Ngày tải lên: 13/08/2014, 16:21

... study in 27 critically ill patients subjected to transnasal endoscopy and intubation of the pylorus. Attending intensive care physicians were trained in the handling of the new endoscope for ... Cresci G: Guidelines for the provision and assessment of nutrition support therapy in the adult critically ill patient: Society of Critical Care Medicine (SCCM) and American Society for...

Ngày tải lên: 14/08/2014, 07:21

... period of pain relief being 5 months. The range of relief for the radiofrequency group was from zero days to 16 months for all 26 patients who underwent the radiofrequency procedure. Of the ... follow-up data 7 12 15 11 . Cryorhizotomy is reported in to be of similar ef- ficacy. In a study of 76 patients treated via CT-guided cryorhizotomy of the dorsal nerve media...

Ngày tải lên: 26/10/2012, 09:32

... determined by the Bradford assay. All protein concentrations reported in this study are expressed in terms of protomers. Chaperone activity assay Chaperone activity was determined by the citrate synthase (CS) ... quaternary structure of a-Hsp proteins is highly dynamic, which is often reflected by pronounced size heterogeneity or rapid subunit exchange [19]. Mammalian members of the a-Hs...

Ngày tải lên: 31/03/2014, 21:21