Báo cáo y học: "New tricks for old NODs" ppsx
Báo cáo y học: "Gene profiling for defining targets for new therapeutics in autoimmune diseases" potx
... lymphocytesReviewGene profiling for defining targets for new therapeutics in autoimmune diseasesLars RoggeImmunoregulation Laboratory, Department of Immunology, Institut Pasteur, Paris, FranceCorresponding ... level in type 1 cells while TRAF5was preferentially expressed in type 2 cells. Members ofthis family serve as adapter proteins that mediate cytokinesignaling; in particular, they seem to play ... P,Austin A, Lad N, Kaminski N, Galli SJ, Oksenberg JR, Raine CS,Heller R, Steinman L: Gene-microarray analysis of multiplesclerosis lesions yields new targets validated in autoimmune encephalomyelitis....
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Báo cáo y học: "New hope for haplotype mapping" pptx
... technology,without it being necessary to type every DNA variant indi-vidually in an attempt to identify the functional polymor-phism responsible for a disease.Until recently, only a few studies ... haplotype networks that can bedefined by a relatively small number of markers.What then should the gene mappers conclude from theseapparently disparate results? By defining haplotypes veryrigorously, ... coulddefine ancestral haplotypes with LD extending over verylarge distances (up to 3 cM) and that the association ofany one of many alleles could implicate a haplotype asso-ciated with disease....
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Báo cáo y học: "New insights into integrin signalling: implications for rheumatoid arthritis synovial fibroblasts" pptx
... transfer to synoviocytes andosteoclasts. J Clin Invest 1999, 104:137-146.14. Pap T, Franz JK, Hummel KM, Jeisy E, Gay RE, Gay S: Activationof synovial fibroblasts in rheumatoid arthritis: lack ... cultured rheumatoid synoviocytes. JRheumatol 1995, 22:817-828.12. Morel JC, Park CC, Zhu K, Kumar P, Ruth JH, Koch AE: Signaltransduction pathways involved in rheumatoid arthritis syn-ovial ... invasion of articular cartilage by rheumatoid synovial fibroblasts is inhibited by antibodies to specific inte-grin receptors and by collagenase inhibitors. Arthritis Rheum1997, 40:1298-1307.10....
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Báo cáo y học: ":New tricks for an old-favorite model" pps
... related to systems and synthetic biology, yeasts as model organisms in gene expression, aging and human disease studies and the use of yeast cells as factories.Yeast as model organism for aging ... larval and adult body sizes. TOR is linked to aging from yeast to mammals and deregulation of the pathway causes disease in humans (such as cancer, cardiac hypertrophy and inflammatory diseases). ... before transcripts are delivered to processing bodies, and it interacts with target transcripts at or soon after their trans-cription. Microarray analysis for cells grown in low iron supply...
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Báo cáo y học: " Unique challenges for appropriate management of a 16-year-old girl with superior mesenteric artery syndrome as a result of anorexia nervosa: a case report" pptx
... of a 16-year-old girl with superior mesenteric artery syndrome as a result of anorexia nervosa: a case reportPhilip A Verhoef*1,2 and Angelika Rampal2Address: 1Department of Internal Medicine, ... patient with anorexia nervosa and superior mesenteric artery syndrome. Case presentation: We report the case of a 16-year-old Caucasian girl who presented to ouremergency department with nausea, abdominal ... Clearly,this combination of pathologies is uniquely challenging:SMA syndrome can precipitate and exacerbate anorexia nervosa because of the nausea associated with a smallbowel obstruction and...
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Báo cáo y học: " New technical approach for the repair of an abdominal wall defect after a transverse rectus abdominis myocutaneous flap: a case report" pot
... ReportsOpen Access Case report New technical approach for the repair of an abdominal wall defect after a transverse rectus abdominis myocutaneous flap: a case reportDaniel A Kaemmer*, Joachim Conze, ... disturbance, these defects canalso lead to adverse interference of the abdominal wall functions, as a thrust bearing for the intraabdominal pres-sure and as an antagonist of the back muscles and part of the ... butrather an abdominal wall defect that had been createddeliberately, and this made a collagen defect unlikely. The use of mesh material was reduced to only augmenting the thinned lateral abdominal...
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Báo cáo y học: "New methodology for specific inhalation challenges with occupational agents" pdf
... equipment for specific inhalation challenges with occupational agents that can allow for alltypes of generation within the same instrument. We alsoassessed the feasibility of its use by hereby presenting ... 112:829-59.6. Cloutier Y, Lagier F, Lemieux R, Blais MC, St-Arnaud C, Cartier A, Malo JL: New methodology for specific inhalation challenges with occupational agents in powder form. Eur Respir J ... validated by direct measurement instrumentFormaldehyde 0.65 mg/m30.63 0.63 0.08 0.87 0.36Formaldehyde 1.0 mg/m31.07 1.06 0.1 1.94 0.74Formaldehyde 1.7 mg/m31.43 1.43 0.04 1.58 1.31Isocyanates...
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Báo cáo y học: "New role for Agrin in T cells and its potential importance in immune system regulation" ppsx
... biology and make the case for a more thorough and systematic investigation into its role in the immune system. â 2010 BioMed Central LtdNew role for Agrin in T cells and its potential importance ... only an assumption and it remains to be seen whether Agrin plays a role in the INF system. A working hypothesis on the function of Agrin in the immune system Although the number of studies investigating ... expression. Agrin from activated T cells has the capacity to induce aggregation of key receptors and to regulate signalling. Interestingly, T cells isolated from patients with systemic lupus erythematosus...
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Báo cáo y học: "New indications for the use of therapeutic hypothermia" doc
... therapeutic hypothermia.Available online http://ccforum.com/content/8/6/E1During the 1950s therapeutic hypothermia (TH) becamewidely used for neurological protection during cardiacsurgery, ... and there were numerous anecdotal reports of the use of TH in the treatment of neurological injury followinghead injury, stroke and anoxic brain injury [1]. For reasons thatare unclear, there ... injuryfollowing asphyxial cardiac arrest. In these conditions, anyCommentaryNew indications for the use of therapeutic hypothermiaStephen Bernard The Intensive Care Unit, Dandenong Hospital, Melbourne,...
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Báo cáo y học: " New horizons: NT-proBNP for risk stratification of patients with shock in the intensive care unit" pps
... IICommentary New horizons: NT-proBNP for risk stratification of patients with shock in the intensive care unitUrsula Hoffmann, Martin Borggrefe and Martina Brueckmann1st Department of Medicine, Faculty ... mortality in the ICU [7]. One method of evaluating patients with shock isinvasive hemodynamic monitoring with PAC. In the modernera, however, non-invasive methods for estimating cardiacfilling ... failure. The diagnostic and prognostic use of natriuretic peptides in the intensive care setting for patients with various forms of shock could be an attractive alternative asnoninvasive markers of...
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Báo cáo y học: " New and old complex recombinant HIV-1 strains among patients with primary infection in 1996–2006 in France: The French ANRS CO06 primo cohort study" potx
... purposes)RetrovirologyOpen AccessResearch New and old complex recombinant HIV-1 strains among patients with primary infection in 1996–2006 in France: The French ANRS CO06 primo cohort studyPierre Frange*1, ... phylogenetic analysis of the strains. CG, LM and CD carried out the coordination of the ANRS PRIMO cohort and have been involved in revising the manuscriptcritically. FS was the physician of the ... Brun-Vezinet F, Meyer L, Costagliola D: French national sentinel sur-vey of antiretroviral drug resistance in patients with HIV-1 primary infection and in antiretroviral-naive chronicallyinfected patients...
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Báo cáo y học: "New and conventional strategies for lung recruitment in acute respiratory distress syndrome" pps
... physiologic responses to a lung recruitment maneuver in acute lung injury and acute respiratory distress syndrome. Respir Care 2008 53:1441–1449.34. Constantin JM, Cayot-Constantin S, Roszyk ... hyperinfl ation of the baby lung due to inhomogeneities in the lung parenchyma, independent of the origin of the injury (pulmonary or extrapulmonary).Recently, we assessed the impact of recruitment ... Bi-Vent+PSV, may also prove a simple and interesting alternative for lung recruitment in the clinical scenario. Certainly, comparisons of diff erent lung recruitment strategies and randomized studies...
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Báo cáo y học: "New versus old blood – the debate continues" docx
... the clinical impact of the duration of red blood cell storage prior to transfusion remains uncertain, and a topic of growing interest.â 2010 BioMed Central LtdNew versus old blood – the debate ... further data – the Age of Blood Evaluation study (Canadian Clinical Care Trials Group) in trauma/intensive care patients and the Red Cell Storage Age Study (US National Heart, Lung, and Blood ... receiving older blood. In a previous issue of Critical Care, Ranucci and colleagues report an adverse outcome in infants receiving older blood during cardiopulmonary bypass (CPB) [1].E ects of blood...
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Báo cáo y học: "New tricks for old NODs" ppsx
... TTyyppee II iinntteerrffeerr oonnss ((aallpphhaa//bbeettaa)) iinn iimmmmuunniittyy aanndd aauuttooiimmmmuunniittyy Annu Rev Immunol2005, 2233::307-336.2. Kato H, Takeuchi O, Sato S, Yoneyama ... tthhrroouugghhccrryyooppyyrriinn//NNaallpp33 Nature 2006, 444400::233-236.23. Mariathasan S, Weiss DS, Newton K, McBride J, O’Rourke K, Roose-Girma M, Lee WP, Weinrauch Y, Monack DM, Dixit VM: CCrryyooppyyrriinnaaccttiivvaatteess ... [[ccoorrrreecctteedd]]ggeennee iinndduuccttiioonn bbyy tthhee iinntteerrffeerroonn rreegguullaattoorryy ffaaccttoorr ffaammiillyy ooff ttrraannssccrriipp ttiioonn ffaaccttoorrss Immunity 2006, 2255::349-360.10....
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Báo cáo y học: "New names for old strains? Wolbachia wSim is actually wRi" ppt
... Biology 2005, Volume 6, Issue 7, Article 401 Iturbe-Ormaetxe et al. http://genomebiology.com/2005/6/7/401Genome Biology 2005, 6:401sequence similarity, fails to distinguishit from other hypotheses. ... slowly to be used for definitive strain identification; in somecases even the wRi and wMelsequences cannot be differentiated.The wsp gene is simply missing fromour wSim assembly, but is 99.9% ... looksmore like wAna than wSim. As should be apparent from this analysis,the assertion made by Iturbe-Ormaetxeet al. that wSim = wRi rests on alogical fallacy; that is, that if the bestunidirectional...
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