Báo cáo y học: " Injurious mechanical ventilation affects neuronal activation in ventilated rat" pot

... Gayle D, Ilyin SE, Flynn MC, Langhans W, Schwartz GJ, Plata- Salamán CR: Pro-inflammatory and anti-inflammatory cytokine mRNA induction in the periphery and brain following intraperitoneal administration ... proteins involved in the inflammatory cascade. Mechanical ventilation triggered lung and systemic inflammatory responses. Compared to LVt, HVt promoted an increase in inflammato...

Ngày tải lên: 14/08/2014, 08:21

... They found that, in patients with COPD who were not ready to sustain spontaneous breathing, the use of invasive or noninvasive ventilation was equally effective in reducing PTPdi and improving ... test. IMV, invasive mechanical ventilation; NPPV, noninvasive mechanical ventilation. Key messages • The combination of early extubation and noninvasive positive-pressure mechanical...

Ngày tải lên: 13/08/2014, 10:20

... alveolar instability. Introduction The treatment of acute lung injury and the acute respiratory distress syndrome remains largely supportive, in the form of mechanical ventilation. However, mechanical ... acute respiratory distress syndrome [34]. Interestingly, a respiratory rate of 24/ minute with a PEEP of 3.5 cmH 2 O was as effective at main- taining PO 2 as a respiratory rate of 7...

Ngày tải lên: 13/08/2014, 03:21

... Group: Noninvasive mechanical ventilation may be useful in treating patients that fail weaning from invasive mechanical ventilation: a randomized clinical trial. Crit Care 2008, 12:R51. 2. Pingleton ... have investigated the preventive or prophylactic use of NPPV immediately after extubation in avoiding extubation failure in comparison with standard medical therapy. In one earl...

Ngày tải lên: 13/08/2014, 08:21

... populations may have influenced our findings. Conclusions Within a specialized respiratory care unit, successful weaning was not increased in tracheostomy compared with translaryngeally intubated ... regular dialysis in our study (32.26% in the tracheostomy group and 26.32% in the translaryngeal tube-intubated patients). This may underlie the increased requirement for hemo- dialysi s...

Ngày tải lên: 13/08/2014, 20:21

... N-terminal sequencing. In addition to five known zinc-binding proteins, nine zinc- binding proteins were newly identified including: acetate kinase (AckA), DnaK, serine hydroxymethyltransferase (GlyA), ... zinc-containing protein with the zinc finger or zinc cluster exist in yeast, which, however, lacks proteins with the hormone receptor-type zinc-binding motif. This type of zinc-binding pro...

Ngày tải lên: 22/02/2014, 04:20

... ladder formation by Py/Zn, indicating that apoptosis induced by Py/Zn is mediated by caspase activation. The p38 MAPK - specific inhibitor SB203580 also inhibited induction of apoptosis by Py/Zn. Although ... bromide; PARP, poly(ADP-ribose) polymerase; Py, pyrithione; TPEN, N,N,N¢,N¢-tetrakis-(2-pyridylmethyl)ethylenediamine; TUNEL, terminal deoxynucleotidyltransferase-mediated dUTP-biotin ni...

Ngày tải lên: 23/03/2014, 21:20

... decreasing at S9 to S11 (when organogenesis is beginning and pluripotency is being lost) are also expressed in hESCs, and that many of these genes are likely to be regulated by pluripotency-promoting ... Using a phenotype-gene ontology analysis, Fang et al. also determined that defects in genes in clusters 1 through 3 were, in general, associated with embryonic lethality and def...

Ngày tải lên: 09/08/2014, 20:22

... heritable in LCLs but imprinted in fibro- blasts, further study of the two cell lines could help identify some of the factors involved in the mechanism of imprinting. Interestingly, another study found ... imprinted only in the LCLs while the other genes were imprinted only in the fibroblasts. Interestingly, 90% of the previously identified imprinted genes (18 o f 20) validated in...

Ngày tải lên: 09/08/2014, 22:24

... Therefore, the neuronal pathway involved in acid secretion induced by low taurine concentrations may predominantly involve in cholinergic neurons. Both TTX and atropine comple- tely inhibited the ... 10 -6 M,butdidnotcompletely inhibit induction by taurine at > 10 -6 M(Figure5A). Atropine, a muscarinic receptor antagonist, completely inhibited the acid secret ion induced by taurine a...

Ngày tải lên: 10/08/2014, 05:21