Báo cáo y học: " High-dose tranexamic acid reduces blood loss in postpartum haemorrhage" pps
... tissue injury can shift the haemostatic equilibrium toward increased fibrinolysis, contributing to coagulopathy and bleeding [9]. Antifibrinolytic agents, mainly tranexamic acid (TA) and aprotinin, ... permitted only in cases involving intractable bleeding. The primary objective was to assess the efficacy of TA in the reduction of blood loss in women with PPH, and the secondary...
Ngày tải lên: 14/08/2014, 08:21
... probe marked in millimiter increments. Bleeding on probing was recorded and the presence of plaque was registred mesially, buccally, distally, and lingually. Data were obtained at baseline before ... Hyaluronan in tissue injury and repair. Annu Rev Cell Dev Biol. 2007;23:435-61 22. Wisniewski H.G and Vilcek J. TSG-6: an IL-1/TNF-inducible protein With anti-inflammatory activity. Cyt...
Ngày tải lên: 03/11/2012, 11:35
... located in introns, rs700518 is a synonymous SNP that does not result in a change in amino acids, and rs10046 and rs4646 are located in the 3’-untranslated region. Genotypes were determined using ... DBP variation in women in the Framingham Heart Study [21]. DBP in patients with T/T genotype was significantly higher than in those without this genotype. This is very int...
Ngày tải lên: 08/08/2014, 16:23
Báo cáo y học: "Evidence for early disease-modifying drugs in rheumatoid arthritis" pps
... 9-month RCT of hydrox- ychloroquine versus placebo in early RA. Three years after the study ended, early DMARD therapy still resulted in less pain and disability. The report by Verstappen and ... Combination Therapy Trial Group: Delay to institution of therapy and induc- tion of remission using single-drug or combination-disease- modifying antirheumatic drug therapy in early rheumatoid...
Ngày tải lên: 09/08/2014, 01:23
Báo cáo y học: "Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage" pps
... (Olympus AX70) and photographed digitally. To obtain optimal staining results various enzymatic pre- treatments were tested, including hyaluronidase (Boe- hringer, Mannheim, Germany; 2 mg/ml in ... amplification. Finally, the signals were detected with Cy5-labeled streptavidin (Dianova). Nuclear staining was again performed with 4,6-diamidino- 2-phenylindole. The sections were evaluated by...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Biology and therapy of fibromyalgia: pain in fibromyalgia syndrome" ppsx
... lancinating and can be readily distinguished from second pain by most study subjects. In contrast, second pain (transmitted by unmyelinated C-fibers), which is strongly related to chronic pain ... pain sensitivity with spreading of hypersensitivity to uninjured sites and the generation of pain by low threshold mechano- receptors that are normally silent in pain processing. Thus, tissue in...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Targeting insulin-like growth factor axis in hepatocellular carcinoma" ppsx
... concentrations. IGF-2 binds to IGF-1R, IGF-2R and binds to insulin receptor only during early fetal development. Insulin binds to insulin receptor, and it binds to IGF-1R/Insulin Receptor hemireceptor ... pro- teins, including ERK and p70 s6k were all effectively inhib- ited by OSI-906 (OSI) [100]. In addition, it inhibited phosphorylated insulin receptor in both primary human hepatocytes...
Ngày tải lên: 10/08/2014, 21:23
Báo cáo y học: "Clinical audit of core podiatry treatment in the NH" ppsx
... pain again using a pain VAS directly after treatment and seven days later, in conjunction with improving func- tional ability in a small group of older adults [5]. A small qualitative study using ... walking, foot hygiene, nail care, foot pain, worry about feet and impact on quality of life. It was used in combination with a visual analogue pain scale (VAS) and a Podiatry Objective Clin...
Ngày tải lên: 10/08/2014, 21:23
Báo cáo y học: "Nipah virus infection and glycoprotein targeting in endothelial cells" ppsx
... motifs: Y 525 in the F protein and di-tyrosine Y 28/29 in the G protein. Mutations in the two other potential basolateral sorting motifs, a di-tyrosine motif in the F protein (Y 542/ 543 ) and a di-leucine ... of both tyrosine signals in the F pro tein led to an apical redistribution in endothelial cells whereas only tyrosine 525 is involved in targeting in epithelial cel...
Ngày tải lên: 12/08/2014, 02:20
Báo cáo y học: "Inflammatory responses to acute pneumovirus infection in neonatal mice" pps
... promoting protection and in vaccination strategies [18-22]. Interestingly, as the mice used in th is study were born to immunologically naïve mot hers, the differences in inflammatory pathology observed ... lagging in expected weight gain for given age, including the youngest mice that present little overt evidence of inflammation. Conclusions: Our findings among the youngest mice may...
Ngày tải lên: 12/08/2014, 02:20