Báo cáo y học: "Adolescent predictors of objectively measured physical activity and sedentary behaviour at age 42: the Amsterdam Growth and Health Longitudinal Study (AGAHLS)" potx
Báo cáo y học: "Adolescent predictors of objectively measured physical activity and sedentary behaviour at age 42: the Amsterdam Growth and Health Longitudinal Study (AGAHLS)" potx
... desirability. Psycho metric properties of the DPI and AMT are presented in table 2.2.3 Objectively measured physical activity levels and sedentary time in adulthood Physical activity was objectively measured ... Twenty-nine years later, at the age of 42,their physical activity and sedentary behaviour were assessed by means of accelerometry. Boys who scored loweron self-sufficiency/recalcitrance and ... were predictors of physical activity at a later age [19,20]. In our study these charac-teristics predicted sedentary time as well. This supports the assumption that physical activity and sedentary behaviour...
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Báo cáo y học: " Baseline predictors of response and discontinuation of tumor necrosis factor-alpha blocking therapy in ankylosing spondylitis: a prospective longitudinal observational cohort study" potx
... interpretation of data and drafted the manuscript; EB and AS participated in the design of the study, performed the acquisition of data, and critically revised the manuscript. EV and HG contributed to the ... contributed to the statistical analysis and interpretation of data and critically revised the manuscript. ML, PH and TJ contributed to the acquisition of clinical data and critically revised the manuscript. ... continuation of TNF-a blocking therapy. These registries showed thatraised inflammatory markers, lower Bath AnkylosingSpondylitis Functional Index (BASFI), and younger age at baseline were associated...
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Báo cáo y học: "Psychosocial predictors of sexual initiation and high-risk sexual behaviors in early adolescence" potx
... predictor of sexual initiation in the final step of the analysis.Psychopathology and Risky Sexual Behavior The second study question investigated whether internal-izing and externalizing psychopathology ... Board and by the local Board of Edu-cation. Parents were informed of the survey at the time of school registration and offered the opportunity to declineparticipation. Prior to survey administration, ... hypotheses, we havedivided the study into two parts. Our first study questionexamines the unique effects of internalizing psychopa-thology and externalizing psychopathology on initiationof...
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Báo cáo y học: " Paternal predictors of the mental health of children of Vietnamese refugees" ppsx
... Norway, to study the long-term effects of trauma, flight, and exile on the offspring of the refugees.Objectives of the study: 1. To study the association between the psychological distress of ... in the analyses of associationsbetween the mental health at T3 in refugee parents and in their children born in exile.Aims of the study 1. To study the association between the mental health of ... as paternal vs. maternal predictors of the children’smental health. Another consequence of the small sampleis that the number of fathers with PTSD at T1 is low.Cautious interpretations of the...
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Báo cáo Y học: Identification of residues critical for activity of the wound-induced leucine aminopeptidase (LAP-A) of tomato pptx
... The tomato LAP-A1 residues Lys354 and Arg431 mayfacilitate catalysis of substrates and/ or stabilization of the gem-diolate reaction intermediate (Table 1, [22]). With the exception of the ... recentidentification of bicarbonate in the active site of the nativeE. coli PepA and blLAP and the influence of bicarbonateon PepA hydrolysis of a chromogenic substrate [24] suggeststhat bicarbonate may ... analysis of the tomato R 431A His6–LAP-A was not possible. Howeverbecause the residual activity of the R431A was < 0.5% and hydrolysis rates of Leu-Leu a nd Leu-Gly by the wild -type tomato...
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Báo cáo y học: "Selective amplification of glucocorticoid anti-inflammatory activity through synergistic multi-target action of a combination drug" ppsx
... ampli-fication, and therefore the safety profile of the very-low-doseglucocorticoid is maintained. At the organism level, the effects of the combination produce the desired anti-inflammatory activity ... Together, these data suggest that tran-scriptional activation may make an important contribution to the anti-inflammatory activity of the combination. The combination of prednisolone and dipyridamole ... model, and ear swelling in the delayed-typehypersensitivity model (Figure 2). These data suggest that the molecular effect of dipyridamole may amplify the anti-inflamma-tory activity of low-dose...
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Báo cáo y học: "Stable expression of a recombinant human antinucleosome antibody to investigate relationships between antibody sequence, binding properties, and pathogenicity" doc
... detect any deposition of humanantibody in kidneys from any of the mice. There was evidence of non-SLE-related pathology, namely, neutrophil infiltration of kidney glomeruli and of the liver, and ... 1 (CDR1) and CDR2 of the light chain and another in CDR2 of the heavychain [18]. One of these arginines, at position 27a in CDR1(R27a) of the B3 λ chain, has arisen by somatic mutation fromserine.Expression ... CHO-B3 and CHO-B3(R27aS) groups is the lack of evidence of deposition of the antibodies in the kidneys of the mice. Onereason for this may be that the level of human IgG measured in the sera...
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Báo cáo y học: "SOX9 transduction of a human chondrocytic cell line identifies novel genes regulated in primary human chondrocytes and in osteoarthritis" docx
... regulatory role in the development of the retina, and mayregulate the synthesis of collagen type II in the vitreous of the eye [40]. Furthermore, disrupted SOX9 expression in the 'oddsex' ... undertook the laboratory work associatedwith real time PCR analysis of the normal and OA cartilagelibraries. PDC performed the statistical analyses, designed and validated the PCR primers, and supervised ... proteinFigure 2Regulation of candidate genes during chondrocyte dedifferentiationRegulation of candidate genes during chondrocyte dedifferentiation. Real time PCR analysis of candidate gene expression...
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Báo cáo y học: "Preclinical characterization of DEKAVIL (F8-IL10), a novel clinical-stage immunocytokine which inhibits the progression of collagen-induced arthritis" ppsx
... nowelucidate the therapeutic potential of this product and whether the targeted delivery of IL10 potentiates the anti-arthritic action of the cytokine in rheumatoid arthritis patients.Introduction The ... aiming at the targeted delivery of anti-inflammatory cytokines at sites of inflammation. We havereported that the L19 antibody, specific to the alternativelyspliced extra-domain B (EDB) of fibronectin ... infiltrating cellsImmunofluorescence analysis of infiltrating cells. At termination of the therapy experiment a comparative immunofluorescence analysis of infiltrating cells from mice treated...
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Báo cáo y học: "Predicting outcome of rethoracotomy for suspected pericardial tamponade following cardio-thoracic surgery in the intensive care unit" ppt
... insufficiency and use of heparin, acetylsalicylic acid and clopidrogel. The type of primary surgery was retrieved. The chart of the rethoracotomy was evaluated for evacuation of clots and pericardial ... routinely. Haemodynamic monitoring was routi-nely done with help of a catheter in the radial artery and either a central venous catheter and/ or a pulmonaryartery catheter (n = 14). The latter allowed ... primary cardiac surgery.Theaimofthecurrentstudywasthereforetoevalu-ate, retrospectively, the clinical, haemodynamic and echocardiographic features that may predict a favourablehaemodynamic...
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