Báo cáo y học: "The impact of the neisserial DNA uptake sequences on genome evolution and stability" potx

... 5.6% of the Z2491 genome and 7.1% of the MC58 genome, but they contained only 2% (38) and 2.6% (51) of the total number of DUSs, respectively (P < 0.001, χ 2 test). These horizontally transferred ... list was then refined by combining the informa- tion on the distribution of similarity of these putative orthologs and the data on gene order conservation...

Ngày tải lên: 14/08/2014, 08:20

... suggest that the active components of the EA extract of TwHF inhibited the initiation of antibody responses but not ongoing antibody production by established plasma cells. Notably, treatment of RA ... 4i,j). Immunofluorescent staining was carried out to determine the impact of treatment on mononuclear cells infiltrating the kid- neys. Both the extent and the den...

Ngày tải lên: 09/08/2014, 07:20

... led the design and analysis of the study and drafted the manuscript. GJP, KD, CPS and KR contributed to the design of the study, interpretation of results, and critical revision of the manuscript. ... Confidential Enquiry into Perioperative Death classification of surgery, as described previously [5]. Survey data and other sources The results of a national...

Ngày tải lên: 13/08/2014, 08:20

... over the progression of cancer; and the second question is whether the PR domain alone possesses anticancer activity. In this study, we quan- titatively analyzed the mRNA expression level of ... expression of the PR domain was examined after 24 hr of transfection with pcDNA/HisMax/PR and the empty vector, respectively. Supernatants (30 g) of the cell lysates w...

Ngày tải lên: 25/10/2012, 11:15

... infiltration, consisting primarily of lymphocytes and monocytes sometimes with small number of eosinocytes, were seen between the necrotic and normal zones. In addi- tion, hyperplasia of fibroblasts ... as the real-time imaging unit of the system, guiding the target tissue volume, monitoring the energy deposition and the therapeutic effect, and also controlli...

Ngày tải lên: 25/10/2012, 11:18

... hydrogen, modification of bonds, potentials of forcefield, and fixation of heavy atom, backbone, and Ca, were performed for molecular mechanics calculations. and then the energy minimization of the model ... to the study of LPL structure and function. LPL shares a high degree of primary-sequence similarity with pancreatic lipase, and the conservation of most of...

Ngày tải lên: 21/02/2014, 15:20

... autolytic inactivation of D-chymotrypsin and the Tyr146 !His and Tyr146!His/Asn147 !Ser D-chymotrypsin mutants dis- played the same half-life and kinetics in both the presence and the absence of Ca 21 ions, ... used. RESULTS The enzymatic activity and molecular stability of the mutants The catalytic activity and the molecular stability of the mutants were...

Ngày tải lên: 22/02/2014, 07:20

... fits to the set of distances. The main advantages of the procedure are simple: the details of the calibration are precisely and unambiguously defined, it is fully automatic, and the family of calculated ... standard cysteine residue in the DYANA library [53]. A pseudoatom was included instead of the HG atom and a bridge was formed by superimposition of the ps...

Ngày tải lên: 22/02/2014, 07:20

... carb- oxylic acid) and carbon monoxide (Fig. 1) [6]. This reaction is rather unusual in that it involves the cleavage of two carbon–carbon bonds and the concomitant production of carbon monoxide. The stoichiometry ... R. Egmond 1 and Martina Huber 3 1 Unilever Research Vlaardingen, the Netherlands; 2 University of Groningen, Laboratory of Biophysical Chemistry, Groningen...

Ngày tải lên: 22/02/2014, 07:20

... glycone and two aglycone binding sites. Calcula- tions for barley a-amylase justify the ‘6 + 2 + (1) model’ prediction. Thebinding areaof barleya-amylase is composed ofsix glycone, two aglycone ... stable and is not hydrolysed by a-amylases therefore, the products of hydrolysis are always b-glycosides. Selection of these glycosides as substrates has been based on their size (DP...

Ngày tải lên: 08/03/2014, 09:20