Báo cáo y học: "Genome assembly forensics: finding the elusive mis-assembly" pdf

... to increase the specificity of mis -assembly detection. In addi- tion, certain types of mis -assembly can only be detected by specific methods, while the sequencing strategy employed may restrict the types ... the sequencing centers to release the details of their assemblies by submitting the complete assembly information to the NCBI Assembly Archive [37]. This community r...

Ngày tải lên: 14/08/2014, 08:20

... diatom specific. CYCB2 CYCA/B;1 CYCB1 CYCD1 CYCH1 CYCP2 CYCP6 CYCP3 CYCP4 CYCP5 CYCL1 CYCP1 CYC-like dsCYC3 dsCYC4 dsCYC2 dsCYC10 dsCYC6 dsCYC8 dsCYC1 dsCYC9 dsCYC5 dsCYC7 dsCYC11 (b) (a) 0h 1h 6h 5h 4h 3h 2h 8h 9h 7h 10h 11h 12h 0h 1h 6h 5h 4h 3h 2h 8h 9h 7h 10h 11h 12h -3.0 ... late during the cell cycle (Figure 6b). As the other dsCYC genes displayed increased mRNA levels during the...

Ngày tải lên: 09/08/2014, 20:21

... are then isolated by immuno- precipitation using antibodies against those factors. The DNA sites bound by the factors are then identified by hybridizing the DNA to a microarray. In this way, the genome ... cells employ to maximize their regulatory options using only a small number of components. Published: 27 January 2005 Genome Biology 2005, 6:206 The electronic version of this art...

Ngày tải lên: 14/08/2014, 14:21

... considered the most puzzling problem in ani- mal systematics and a major open-ended subject in evolutionary biology. The monophyly of the Ecdysozoa group, strongly championed by the evo-devo community ... that strongly supports the Ecdysozoa hypothesis and at the same time demonstrates that the LBAE biases the position of Caenorhabditis elegans in the phylogenetic tree. We s...

Ngày tải lên: 14/08/2014, 14:21

... 2 Other links UCSD Virtual Difficult Airway Cart – http://anes-som.ucsd.edu/Airway/index.html This site allows visitors to explore a difficult airway cart as they are prepared at the University ... this is the consensus statement from the American Society of Anesthesiologists presenting the evidence (or lack thereof) and recommendations for different airway management options. Sponso...

Ngày tải lên: 12/08/2014, 20:20

... In the case of HIV-1, the unmyr-MA structure was resolved both by NMR [17,18] and crystallography [19], while the myr-MA structure was resolved by NMR only [20].HIV-1unmyr-MA(aswellasSIV,butneither EAIV ... affi- nity of the interaction with PI(4,5)P 2 . The switch from the [T] to the [R] conformation may have further implications at the level of the entire Gag protein, thus...

Ngày tải lên: 13/08/2014, 01:20

... formation. The prevention of catheter/tubing occlusion thus eliminates the need for applying positive pressure to restore IV line patency and clot embolization. Also it benefits the anaes- thesiologist ... inflation. Also backflow of blood into the IV tubing when the cuff is inflated and the temporary stasis which occurs predisposes to clotting of blood in the IV tubing/catheter...

Ngày tải lên: 13/08/2014, 23:20

... 'theoretical 2× assembly& apos; by taking as input the high quality draft assembly and removing all the reads that were not present in the randomly selected set used to generate the canine 2× assembly. ... [9]. Assisted assembly algorithm The assisted assembly process starts by simultaneously build- ing a de novo assembly from the reads and by aligning the same re...

Ngày tải lên: 09/08/2014, 20:20

... DNA REPLICATION-COUPLED CHROMATIN ASSEMBLY The majority of chromatin assembly is tightly coupled to DNA replication in the cell. Accordingly, chromatin assembly systems that preferentially assemble chromatin onto ... with the available data is that activation of Rad53 by the DNA damage checkpoint releases ASF1 into the vicinity of the DNA lesion in order to contribute to th...

Ngày tải lên: 31/03/2014, 21:21

... less) and there was some sample duplication between them. The other factor that may contribute to the diversity of strongly associated SNPs between different studies is the heterogeneity of the disease ... susceptibility allele in that gene. Further complexity arises because not only do particular individuals carry different combinations of risk alleles, but the genotyping chips do...

Ngày tải lên: 09/08/2014, 14:22