Báo cáo y học: " Functional diversification of duplicate genes through subcellular adaptation of encoded proteins" doc

... >1 0 10 20 30 40 D-pair S-pair d N % of genes Illustration of the different evolutionary fates of (functional) duplicate genesFigure 2 Illustration of the different evolutionary fates of (functional) duplicate genes. Each ... work is properly cited. Subcellular localization of duplicate genes& lt;p>Analysis of the subcellular localization patterns of dupli...

Ngày tải lên: 14/08/2014, 08:20

... mechanism of functional divergence of ar-C enhancers of duplicated shh genes in zebrafishFigure 6 (see following page) The mechanism of functional divergence of ar-C enhancers of duplicated shh genes ... support of this hypothesis [11-13,74-76]. However, the mechanisms of regulatory evolution are still poorly Functional analysis of shha and shhb ar-C conserved moti...

Ngày tải lên: 14/08/2014, 07:21

... exhibited decreased motility. These data imply that subcellular localization of claudin-1 can be controlled by phosphorylation, dicating effects on metastatic capacity. Key words: Claudin, melanoma, ... check-point of cell cycle progression. International journal of immunopathology and pharmacology 2006;19(2): 287-291 11. Kenessey A., Sullivan E.A., and Ojamaa K. Nuclear localiza...

Ngày tải lên: 03/11/2012, 11:17

... University (Grant No. 2008CL06). Author details 1 Immunology and Reproductive Biology Lab, Medical School & State Key Laboratory of Pharmaceutical Biotechnology, Nanjing University, Nanjing, ... experiments. (D) Effect of isotype antibody on cell migration. IS: isotype antibody; V:VEGF neutralizing antibody; BGC/STC+IS: BGC/STC cell supernatants added with isotype antibody; BGC/STC+V:...

Ngày tải lên: 10/08/2014, 05:21

... targeting, cytoskeletal anchoring and signal transduction. Additionally, we evaluated the functional pathways in which the ethanol-regulated genes were involved using KEGG (Kyoto Encyclopedia of Genes ... One-Cycle cDNA Synthesis Kit (Affymetrix). Fifteen micrograms of labeled and fragmented cRNA were subsequently hybridized to a Human Genome U133 plus 2.0 microarray (Affym...

Ngày tải lên: 31/10/2012, 15:28

... potentiated by enzymatic degradation of phospholipids [7,44]. The capacity of DM64 to inhibit the myotoxicity induced by myotoxins I (Asp49) and II (Lys49) from B. asper venom was analyzed in vivo ... three domains and are present in the inhibitory receptors of Fig. 6. Inhibition of in vitro cytotoxicity of myotoxins I or II by DM64. Cytotoxicity was analyzed in vitro using C2C12 sk...

Ngày tải lên: 21/02/2014, 01:21

... variants produced by p26-ND60 and p26-alpha were pr esent but recognized poorly by antip26 antibody. To determine if recognition of p26-ND60 and p26-alpha encoded polypeptides by antibody to p26 was ... H.S., Han, Y. & Fung, B.K K. (2000) Subunit e xchange of small h eat sho ck proteins. Analysis of olig- omer formation of aA-crystallin and Hsp27 by fluorescence res- onance ener...

Ngày tải lên: 22/02/2014, 04:20

... was analysed by FACS. RESULTS Functional expression of a Myc-his tagged version of CCR5, and a his-tagged version of CD4 Because the post-translational modifications of CCR5, such as tyrosine ... obtained by limiting dilution and analysed by FACS using the antibody 2D7 (Fig. 1), which recognizes CCR5 [36]. Western blot analysis of the cloned protein from a postnuclear supernatant...

Ngày tải lên: 08/03/2014, 09:20

... hibitor of reCBG [the hydrolysis of 4NP-b- D - glucopyranoside (10 m M ) was reduced by 98% in the presence of 4NP-b- D -mannopyranoside (10 m M )]. Hydrolysis of xenobiotic glycosides by reCBG The ... puri®cation of CBG and allowed characterization in s ome detail, especially with respect to its glycone/aglycone speci®city a nd ability to catalyse the hydrolysis of dietary xenobi...

Ngày tải lên: 08/03/2014, 16:20

... .D. (2001 ) Biosynthesis of the linkage region of glycosaminoglycans: c loning and activity of galactosyltransferase II, the sixth member of the b1,3galactosyltransferase f amily (b3GalT6). J. ... and Thierry Hennet Institute of Physiology, University of Zu È rich, Switzerland The b1,3-glycosyltransferase enzymes identi®ed to date share several conserved r egions and c onserved c...

Ngày tải lên: 08/03/2014, 16:20