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Báo cáo y học: "Functionally important segments in proteins dissected using Gene Ontology and geometric clustering of peptide fragments" potx

Báo cáo y học:

Báo cáo y học: "Functionally important segments in proteins dissected using Gene Ontology and geometric clustering of peptide fragments" potx

... Biology 2008, 9:R52Open Access2008Manikandanet al.Volume 9, Issue 3, Article R52MethodFunctionally important segments in proteins dissected using Gene Ontology and geometric clustering of peptide ... predict important fragments for all proteins, since every protein has a function. In principle, this is possi-ble as we can extend the coverage of our method by varyingthe clustering parameters, and ... EF hand[8] and zinc-binding [9], chitin-binding [10] and ATP/GTP-binding motifs [11], are well known examples of fragment-based functional three-dimensional structural signatures in proteins. ...
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Báo cáo y học: "Estimated intelligence quotient in anorexia nervosa: a systematic review and meta-analysis of the literature" pot

... neuropsychology in AN, thepresent systematic review focused on AN only.AN is the most severe ED affecting mainly, but notonly, young women, and has the highest rate of mortalitylinked to a psychiatric ... moderate and high heterogeneity [26].The analyses were repeated excluding one study at atime to investigate the influence of each individual studyon the overall meta-analysis summary using Stata’s ... Annals of General Psychiatry 2010, 9:40http://www.annals-general-psychiatry.com/content/9/1/40Page 10 of 10as when the meta-analysis was re-estimated omittingeach study in turn, no single study...
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Báo cáo y học: "Line bisection performance in patients with generalized anxiety disorder and treatment-resistant depressionLine bisection performance in patients with generalized anxiety disorder and treatment-resistant depression"

... PI in the Department of Clinical Psychology and Psychiatry, Zhejiang University School of Medicine. His current team work includes the clin-ical psychology and clinical psychiatry, being ... Department of Clinical Psychology and Psychiatry, Zhejiang University School of Medicine, Hangzhou, China; 3. Department of Psychiatry, Second Hospital, Zhejiang University School of Medicine, Hangzhou, ... doctoral fellow in the De-partment of Clinical Psy-chology and Psychiatry, Zhejiang University School of Medicine. Her current research interests include the neurocognitive aspects of treatment-resistant...
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Báo cáo y học: "Hormone replacement therapy in rheumatoid arthritis is associated with lower serum levels of soluble IL-6 receptor and higher insulin-like growth factor 1" doc

... Baylink DJ, af Ekenstam E, Lindh E, Mohan S,Ljunghall S: Circulating levels of insulin-like growth factor-I and -II, and IGF- binding protein-3 in inflammation and afterparathyroid hormone infusion. ... safety vari-ables on their entry into the study and after 12 and 24 months, using vaginal ultrasonography and cytology. E2 in serum was measured (approximately 12 hours aftertablet intake) by ... radioimmunoassay (Clinical AssaysTM,DiaSorin, Vercelli, Italy) at baseline and yearly thereafter.BMD in the left total hip and lumbar spine was measuredby dual-energy x-ray absorptiometry (DXA) with...
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Báo cáo y học: "Regulatory T cells in systemic lupus erythematosus: past, present and future" pot

... Finally, lymphocyte production of IL-2 and the mature form of TGFβ is decreased in SLE(reviewed in [3]), and these are the cytokines required for thegrowth and functional activity of Tregs.An important ... DA, Gray JD, editors: The interaction of T cells withcells of the innate immune system and B cells in the patho-genesis of SLE. In Dubois’ lupus erythematosus. 7th edition.New York: Lippincott ... E, Zinger H, Nyska A, Mozes E: Prevention of systemiclupus erythematosus-like disease in (NZBxNZW)F1 mice bytreating with CDR1- and CDR3-based peptides of a patho-genic autoantibody. J Clin...
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Báo cáo y học: " Coronary arterial calcification in rheumatoid arthritis: comparison with the Multi-Ethnic Study of Atherosclerosis" pps

... nature of the analysis, and the discrepancymay be the result of random variability. Importantly, a singlemeasurement of inflammatory cytokines is not representative of the total inflammatory burden ... coro-nary plaques, thereby precipitating acute thrombosis and clinical CV events [13]. Interestingly, atherosclerotic plaque and rheumatoid synovium share an array of inflammatory cells and cytokines ... Current and past use of glucocorticoids and of biologic and nonbiologic DMARDs was ascertained by inter-view. Single-view, anterior–posterior radiographs of the hands and feet were obtained and...
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Báo cáo y học: "Antiphospholipid antibody profiles in lupus nephritis with glomerular microthrombosis: a prospective study of 124 cases" pot

... creatinine, and proteinuria, aswell as the frequency of systemic hypertension, were all signif-icantly greater in patients with GMT. Taken together, GMT maybe an important cause of renal injury ... plasmin, and hinder the antithrombininactivation of thrombin. The purpose of this study was toinvestigate the prevalence of GMT in LN patients and examinethe relation between the aPL profiles ... tissue injury activity and chronicity indices;elevated serum creatinine, blood urea nitrogen, and proteinurialevels; a lower serum C3 level and much intense glomerular C3,C1q staining; and a...
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Báo cáo y học: "Chronic nonbacterial osteomyelitis in childhood: prospective follow-up during the first year of anti-inflammatory treatment" potx

... choose in this regard.Conclusions In summary we found a sustained response after 1 year of anti-inflammatory treatment using NSAIDs, and in cases of insuf ficient response sulfasalazine plus ... ferritin,117 μg/l), and in patients with large numbers of radiolo-gical inflammatory bone lesions, especially with involve-ment of the spine or diaphyses of long bones. Patientsinitially presenting ... effect. Themajor findings of our prospective s tudy were a rapidimprovement of disease activity, pain and physical func-tion going along with a reduction of predominantly clini-cal lesions...
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Báo cáo y học: "Inhaled nitric oxide in acute respiratory distress syndrome with and without septic shock requiring norepinephrine administration: a dose–response study" ppt

... cessation of inhaledNO.Hemodynamic and respiratory effects of NO in patients with septic shockHemodynamic and respiratory effects of increasing inspira-tory concentrations of NO in patients ... absence of septicFigure 4Individual changes in MPAP and PaO2/FiO2 induced by increasing inspiratory intratracheal concentrations of inhaled NO (Insp IT NO) in eight patients with ARDS and ... 3, methemoglobin and NO2 significantlyincreased at inspiratory NO concentrations of 15 ppm. ATable 5Respiratory effects of increasing inspiratory concentrations of inhaled NO in eight patients...
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Báo cáo y học: " Increased proviral load in HTLV-1-infected patients with rheumatoid arthritis or connective tissue disease" potx

... Standardcurves were generated using ten-fold serial dilutions of adouble standard plasmid (pcHTLV-ALB) containing onecopy of the target regions of both the HTLV-1 pol gene and the cellular albumin gene. ... T lymphocytes (CTL) intothe central nervous system is a critical step in the patho-genesis of HAM/TSP [31,32]. Similarly, infiltration of Tcells plays a central role in the initiation and ... expression of adhesion molecules potentially involved in the migra-tion of lymphocytes into the spinal and joint compart-ments [17]. Secondly, HTLV-1 might be transmitted fromthe infiltrated T lymphocytes...
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