Báo cáo y học: "Cross-kingdom patterns of alternative splicing and splice recognition" docx
Báo cáo y học: "Cross-kingdom patterns of alternative splicing and splice recognition" docx
... employed and the frequencies of splicing vary
among organisms. Bacteria and archaea lack the spliceosomal
pathway and splice infrequently via self -splicing introns.
Among unicellular eukaryotes, ... demonstrated
experimentally in the yeasts Saccharomyces and Schizosac-
charomyces [17,27], and in plants [42]. Our analysis extends
this result to all ascomycetes, as well as bas...
Báo cáo y học: "Global analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cells" ppt
... mRNA isoforms induced by insulin and winglessFigure 2
Numerous changes in alternatively spliced mRNA isoforms induced by insulin and wingless. (a) Features of microarray design. The array contains ... global impact
of signaling cascades on alternative splicing (reviewed in [24-
26]). Only a handful of examples of signal-induced alternative
splicing have been identified an...
Báo cáo y học: "κ The roles of the classical and alternative nuclear factor-κB pathways: potential implications for autoimmunity and rheumatoid arthritis" ppsx
... classical and alternative pathways of NF-κB activation
regulate survival and activation of T and B lymphocytes at
their sites of development in thymus, bone marrow and
spleen, and in the periphery. ... many inflammatory conditions may be
partly or largely driven by Th17 and not by Th1, as was
erroneously concluded previously [88,93-96]. Th17 and/ or
IL-17 have been report...
Báo cáo y học: " Differential patterns of intronic and exonic DNA regions with respect to RNA polymerase II occupancy, nucleosome density and H3K36me3 marking in fission yeast" pps
... (2,218 and 2,598 genes, respectively). Lists of
spliced/un spliced genes were then ranked in descending
order and split into 10 equal groups (approximately 220
and 260 genes per group for spliced and ... Differential patterns of intronic and
exonic DNA regions with respect to RNA polymerase II occupancy,
nucleosome density and H3K36me3 marking in fission yeast. Genome
Biolog...
Báo cáo y học: "Differential patterns of histone acetylation in inflammatory bowel diseases" potx
... global loss of acetylation lysine16
and trimethylation of lysine 20 of histone 4 is a com-
mon hallmark of human tumour cells [23]. Here, we
investigate the pattern of histone 4 acetylation and its
localization ... difference in acetylation. Peyer’s patches
showed the highest levels of K5 and K16 acetylation.
Finally, in biopsies of inflamed bowel and in Peyer’ s
patches...
Báo cáo y học: "Differential patterns of histone acetylation in inflammatory bowel diseases" pptx
... global loss of acetylation lysine16
and trimethylation of lysine 20 of histone 4 is a com-
mon hallmark of human tumour cells [23]. Here, we
investigate the pattern of histone 4 acetylation and its
localization ... difference in acetylation. Peyer’s patches
showed the highest levels of K5 and K16 acetylation.
Finally, in biopsies of inflamed bowel and in Peyer’ s
patches...
Báo cáo y học: "The impact of study design and diagnostic approach in a large multi-centre ADHD study. Part 1: ADHD symptom patterns" ppsx
... Developmental and Psychiatry Centre, Institute of Psychiatry,
London, UK.
4
Department of Child and Adolescent Psychiatry and
Psychotherapy, Central Institute of Mental Health, J 5, Mannheim, Germany.
5
Department ... Psychology,
University of Southampton, Southampton, UK.
15
Departments of Psychiatry
and of Neuroscience and Physiology, SUNY Upstate Medical University,
S...
Báo cáo y học: "Distribution patterns of small-molecule ligands in the protein universe and implications for origin of life and drug discovery" doc
... 3,5,7-trihydroxy-2-(4-
hydroxyphenyl)-4h-chromen-4-one, 5-hydroxy-2-(4-hydrox-
yphenyl)-1-benzofuran-7-carbonitrile, 3,3',5,5'-tetraiodothy-
roacetic acid, 3,5,7,3',4'-pentahydroxyflavone ... bio-ligands
An early bio-ligand is defined as that owned by both prokary-
otic (E. coli) and eukaryotic (yeast or higher) species, while a
late bio-ligand is defined as that owned o...
Báo cáo y học: "Distinct patterns of SSR distribution in the Arabidopsis thaliana and rice genomes" pptx
... 1 and 6 base-
pairs (bp)) in DNA sequences. They can be found in any
genome (both eukaryote and prokaryote) and in any region
(protein coding regions and non-coding regions). Histori-
cally, ... (repeat type), N(M
t
) is the
expected number of times that, in a DNA segment of length N,
we find t consecutive Ms, L is the length of M, and p(M) is the
probability of M (obtained...
Báo cáo y học: "Mutation patterns of amino acid tandem repeats in the human proteome" ppt
... divided it by the total number of synonymous and
non-synonymous positions analyzed (Figure 2 and Additional
data file 1). In the two types of regions, the frequency of non-
synonymous substitutions ... frequency of syn-
onymous and non-synonymous substitutions inside repeats
and in repeat adjacent regions. We identified all the synony-
mous and non-synonymous nucleotide chan...