Báo cáo y học: "Analysis of 142 genes resolves the rapid diversification of the rice genus" pdf

... file 5Results of testing the effect of rate bias caused by the fast-evolving genes of the F-genomeResults of testing the effect of rate bias caused by the fast-evolving genes of the F-genome.Click ... gene. Discussion This study fully resolved the phylogeny of the rice genomes. Through extensive tests and analyses, we demonstrate that the phylogenetic rec...

Ngày tải lên: 14/08/2014, 08:20

... of polymorphic genes may act in concert in the pathogenesis of SLE, a concept that may be instrumental in the analysis of the genetics of SLE as well as providing hypotheses for pathways in the ... investigate whether a combination of polymorphic candidate genes, tentatively thought to be involved in the pathogenesis of SLE, could further elucidate the genetic basi...

Ngày tải lên: 09/08/2014, 01:24

... 0.005). Further analysis of the distribution of individual Vκ genes in the productive Vκ gene repertoire revealed a significantly higher frequency of the gene A27 in the parotid gland of the patient ... memory B cells accumu- late in the parotid gland but cannot clarify the origin of these cells. Whatever the primary aberration in the induc- tion of the saliv...

Ngày tải lên: 09/08/2014, 03:24

... or affinity of these IgG receptors or that enhance their ability to bind spe- cific IgG isotypes may therefore play an important role in deter- mining the severity and persistence of inflammation ... participated in the collection of clinical data and the recruitment of patients into the study. DS, JR and VK undertook some of the genotyping assays on DNA prepared in the...

Ngày tải lên: 09/08/2014, 07:20

Ngày tải lên: 09/08/2014, 07:20

... reference gene if the reference genes are selected through the use of a stability algorithm [21], although in this study one of the genes identi- fied by the algorithm (SDHA) was not stably expressed ... or the phenotyping and selec- tion of samples through histological grading may have increased the statistical powers of each of these differences observed, as the...

Ngày tải lên: 09/08/2014, 08:22

... with the inflammatory activity in sys- temic vasculitis, thereby confirming the role of these proteins in inflammatory reactions of endothelia [47]. Although the gen- eral consensus is that the ... could further promote the synthesis of pro-inflammatory cytokines, the influx of inflammatory cells, and fibrinogenesis, whereas the downregulation of GSTP, Cu–Zn SOD and cy...

Ngày tải lên: 09/08/2014, 08:22

... of C4 in these mice, and that the loss of the major negative regulator of the classical complement pathway fails to impact disease severity, the use of the MRL mouse as a prototypical model of ... planned and performed the majority of the experiments and was primary author of the manuscript. KS performed the hemolytic assays and assisted in interpreting the d...

Ngày tải lên: 09/08/2014, 10:21

... raises the question about the role that this variety of intra- articular bacterial DNA plays in the pathogenesis of ReA and other forms of arthritides. However, detection of bacterial DNAs in the ... Staphylococcus aureus) or simply of nonmethylated CpG motifs is sufficient to trigger arthritis in mice [49-51]. The hypothesis is that bacterial DNA may be directly responsib...

Ngày tải lên: 09/08/2014, 10:23

... 0.0006). Genotype analyses of all of the other SNPs yielded findings similar to those of the allele frequency comparisons, and no differences were found by sex stratification in any of them (not shown). ... J: Re-evalu- ation of putative rheumatoid arthritis susceptibility genes in the post-genome wide association study era and hypothesis of a key pathway underlying suscep...

Ngày tải lên: 09/08/2014, 14:20