Báo cáo y học: " Proteomic view of mitochondrial function" ppsx

... 152 showed modulation of citrate synthase activity. Obviously, as the activity of only a single enzyme was monitored, this study probably missed many modifiers affecting other mitochondrial activities. The ... components of mitochondrial import systems (Mohr-Tranebjaerg syndrome) and mitochondrial morphology (dominant optic atrophy, Charcot-Marie- Tooth neuropathy type 2A, Wolf-Hi...

Ngày tải lên: 14/08/2014, 08:20

... biology and biochemistry have enabled analy- sis of the expression profiles of numerous proteins at once. In this study, we looked at hypoxia-induced apoptosis and, by using the Western array ... to identify key molecules in the course of hy- poxia-induced apoptotic pathways. Such analysis of trophoblastic cells will, in the near future, yield in- sights into the mechanisms of p...

Ngày tải lên: 31/10/2012, 15:12

... dependency] of individual mitochondrial- type AACs in order to identify differences in the function of the various isoforms and to understand the repeated evolution of AAC isoforms in a variety of organisms. We ... Kaiserslautern, Germany; 2 Department of Evolutionary Microbiology, Faculty of Science, Catholic University of Nijmegen, the Netherlands The expression of mitocho...

Ngày tải lên: 18/03/2014, 01:20

... USA. 5 Department of Pharmaceutical Sciences, University of Chicago Pritzker School of Medicine, Chicago, IL, USA. 6 Section of Hematology/Oncology, Department of Medicine, Northshore University Health Systems, ... USA. 7 Section of Cardiac and Thoracic Surgery, Department of Surgery, University of Chicago Pritzker School of Medicine, Chicago, IL, USA. 8 Department of Heal...

Ngày tải lên: 10/08/2014, 09:22

... activity, regardless of its origin, may be common to multiple types of lipodystrophy. However, it cannot be excluded that PPARγ down-regulation is an effect, and not a primary cause of the APL syndrome, ... molecular basis of lipoatrophy in acquired partial lipodystrophy, we examined gene expression in adipose tissue from this patient newly diagnosed with acquired partial lipodystroph...

Ngày tải lên: 11/08/2014, 21:22

... identification of proteins via tandem mass spectrometry analysis. Here, we measured the proteomic profile of mesenteric lymph to identify underlying processes involved in the disease physiology of shock. Results Differential ... automatically matched by the software to the Sypro st ained image of the preparative gel. Of the 166 spots excised, digested enzymatically with trypsin, a...

Ngày tải lên: 13/08/2014, 13:20

... 17:1-8. 4. Kural-Seyahi E, Fresko I, Seyahi N, Ozyzgan Y, Mat C, Hamuryudan V, Yurdakul S, Yazici H: The long term motrality and morbidity of Behçet syndrome. A 2-decade outcome survey of 387 patients ... fol- lowing days. Clinical assessment and vascular studies were repeated on day 7. Brachial artery reactivity Endothelial function was studied, noninvasively, by means of brachial art...

Ngày tải lên: 09/08/2014, 10:21

... assembly of the data sug- gested otherwise, yielding a tremendous diversity with approximately 1.2 million genes identified, most of which have no exact matches to any known sequences. Most notably, ... their ability to recapitulate expression patterns of nearby genes using a simple reporter-gene assay in the embryo. When compared with Drosophila pseudoobscura, sequence identity could n...

Ngày tải lên: 14/08/2014, 14:21

... Project of the Japanese Ministry of Public Welfare and Labor. Author details 1 Dept. of Surgery I, Tokyo Medical University, Tokyo, Japan. 2 Diagnostic Pathology, Division, Tokyo Medical University, ... Ostmark B, Benson NA: Heterogeneity of aldehyde dehydrogenase expression in lung cancer cell lines is revealed by Aldefluor flow cytometry-based assay. Cytometry B Clin Cytom 2007, 72:...

Ngày tải lên: 10/08/2014, 09:22

... arbitrary Table 7 Summary of purine and pyrimidine metabolic pathways of Polynucleotide nucleotidyl transferase Query gene Pathway Count and ratio p-value q-value Web site SA3 Pyrimidine metabolism ... eukaryotic messenger RNA by means of the polymerase chain reaction. Science 1992, 257:967-971. 17. Yun-Jee KIM, Chae-ll KWAK, Young-Yun GU, In-Taek H, Chun Jong- Yoon: Annealing control p...

Ngày tải lên: 11/08/2014, 21:21