Báo cáo y học: "Exploring systemic RNA interference in insects: a genome-wide survey for RNAi genes in Tribolium" potx

... (Piwi/Argonaute/Zwille) domain, tandem RNase III domains and a carboxy-terminal dsRNA binding domain. A single Dicer protein is involved in both the siRNA and miRNA pathways in C. elegans [67-69]. ... pathway and miRNA path- way are essentially parallel, using related but distinct proteins at each step. For instance, in Drosophila, Dicer2, R2D2 and Argonaute2 are involved in the...

Ngày tải lên: 14/08/2014, 08:20

... 5’-AATGATACGGCGACCACCGACTAAAGTAGCCCCTTGAATTC- 3’ p7+Loop: 5’-CAAGCAGAAGACGGCATACGATAGTGAAGCCACAGATGTA-3’ PCR was performed on PTC-225 3DNA Engine Tetrads (Bio-Rad) using Amplitaq Gold polymerase and ... can be partially mitigated at the statistical analysis stage (see below), careful library preparation and quality control can minimise variance in shRNA representation. Lentiviral Pack...

Ngày tải lên: 09/08/2014, 23:20

... Paola Solano - paola.solano@alice.it; Valentina Vinciguerra - vinciguerraV77@libero.it; Pantaleo Fornaro - pantaleo.fornaro@unige.it * Corresponding author Abstract Our aim was to present a ... receptor antago- nism. Additionally, SRI-refractory OCD and OCRDs patients may have additional dysfunctional abnormalities in dopaminergic pathways that may require augmenta- tion with DA-blocki...

Ngày tải lên: 08/08/2014, 23:21

... selectively after exposure to inflammatory media- tors or trauma, and has a role in inflammation and pain [7]. In randomised controlled clinical trials, selective COX-2 inhibi- tors have demonstrated a ... observational studies [13]. Randomised controlled clinical trials are designed to evaluate the efficacy of a certain strategy, and despite including thousands of patients they may...

Ngày tải lên: 09/08/2014, 10:20

... Sierra Quiroga 1 , Anxo Martinez de Alegria 2 , Jose Manuel Suarez Peñaranda 3 Abstract Background: As the population ages, bioprosthesis are increasingly being used in cardiac valve replacem ... Compostela University Hospital. La Choupana, Santiago de Compostela 15706, Spain. 2 Department of Radiology, Santiago de Compostela University Hospital. La Choupana, Santiago de Compostela 15706, S...

Ngày tải lên: 10/08/2014, 09:22

... significant for right breast ductal carcinoma in situ for which she had undergone lumpectomy and whole breast radiation therapy nine years previously. Mammography and magnetic resonance imaging ... the case of a woman who developed squamous cell carcinoma of the nipple nine years after conservative surgery and radiation for ductal carcinoma in situ of the ipsilateral breast. W...

Ngày tải lên: 11/08/2014, 12:20

... circu- lating growth factors that normally are inactivated in the lungs. Pulmonary shunting caused by the several disease processes that are associated with HOA causes a faulty pulmonary clearance ... the facial tissues, which may simulate acromegaly [3] and finally, neurovascular changes of the hands and feet including chronic erythema, paresthesia and increased sweating. Most commonly i...

Ngày tải lên: 11/08/2014, 23:21

... not for citation purposes) 25. Nakaya M, Dohi M, Okunishi K, Nakagome K, Tanaka R, Imamura M, Baba S, Takeuchi N, Yamamoto K, Kaga K: Noninvasive system for evaluating allergen-induced nasal hypersensitivity ... hyperresponsiveness (AHR) is a functional abnor- mality characteristic of bronchial asthma [1]. AHR in asthma is defined as an exaggerated response of the airway (lower airway...

Ngày tải lên: 12/08/2014, 14:20

... sufficiently succinct for a clear cut decision, and therefore"mainstream” answers were based on the remaining 8 questions. Quality of data For validation purposes we obtained information on all the ... week-data were there in case some respondents on the day of the survey had an unusual number of MC-patients. Analysis and presentation of data In the analyses, the variables ag...

Ngày tải lên: 13/08/2014, 14:20

... (LA), and embryonic A- class (EA) microarray datasetsEnriched genes from the larval pan-neural (LP), embryonic pan-neural (EP), larval A- class (LA), and embryonic A- class (EA) microarray datasets.Click ... data file 27RMA intensities for the larval pan-neural (LP), larval A- class (LA), and larval reference (LR) datasetsRMA intensities for the larval pan-neural (LP), larval A- cl...

Ngày tải lên: 14/08/2014, 07:22