... Sciences, University of Maryland Medical School, Baltimore, Maryland 21201, USA. ¥ Department of Plant Biology, Michigan State University, East Lansing, Michigan 48824, USA. Correspondence: ... #296, University of Maryland, College Park, Maryland 20742, USA. § Computation Directorate, Lawrence Livermore National Laboratory, 7000 East Avenue, Livermore, California 94550...
Ngày tải lên: 14/08/2014, 08:20
... specificity and robustness of pathway activity for signaling pathways: implications for whole genome RNAi screens The specificity of proteins regulating the activity of cell sign- aling pathways is ... Hence, Cell type specificity for signaling pathwaysFigure 4 Cell type specificity for signaling pathways. The basal activity and fold induction by Wg or ΔNLrp6 is different in the varie...
Ngày tải lên: 14/08/2014, 08:20
Báo cáo y học: "Utrecht, The Netherlands. ¶Department of Integrated Biosciences, The University of Tokyo" docx
... and Technology Corporation, Yoshida-kawaramachi, Sakyo-ku, Kyoto, 606-8305, Japan. ‡ Department of Mutagenesis, Radiation Biology Center, Kyoto University, Yoshida Konoe, Sakyoku, Kyoto 606-8501, ... and Technology Laboratory, Kyoto University, Yoshida Konoe, Sakyo- ku, Kyoto 606-8501, Japan. † Kondoh Differentiation Signaling Project, Exploratory Research for Advanced Technology (ERATO)...
Ngày tải lên: 14/08/2014, 17:22
Báo cáo y học: "Cancer genomics identifies determinants of tumor biology" ppt
... because α-KG is required by prolyl hydroxy- lases, enzymes that hydroxylate and promote the degra- dation of hypoxia-inducible factor 1α (HIF-1α), the intra- cellular levels of HIF-1α were also characterized. ... discovery in cancer In a 1956 paper [1], Otto Warburg observed that the predominant mode of energy production in cancer cells was by aerobic glycolysis rather than by oxidati...
Ngày tải lên: 09/08/2014, 20:21
Báo cáo y học: "The ups and downs of biological timers" pdf
... sensitivity in all cases (fig. 1). c-e, Delay time sen- sitivity as a function of η and P T for the cases of accumulation (c), decay (d) and non-linear decay (e). The logarithm of the delay time ... mechanisms that survey the successful completion of the critical events occurring dur- ing those cell-cycle stages. Alternatively, protein decay may actually occupy a longer portion o...
Ngày tải lên: 13/08/2014, 22:22
Báo cáo y học: "Exploring the transcriptional landscape of plant circadian rhythms using genome tiling arrays" potx
... analysis of each microarray time courseSpectral analysis of each microarray time course.Click here for fileAdditional data file 2Spectral analysis of each microarray time courseSpectral analysis ... forms of ncRNA are well known to be an integral part of genomes, yet many of these transcripts, described here and by others, detected by tiling arrays in several organisms fail to qua...
Ngày tải lên: 14/08/2014, 21:20
Báo cáo y học: "The 32nd Annual Congress of the Society of Critical Care Medicine, 28 January – 2 February 2003, San Antonio, USA" pdf
... following stimulation by Gram- negative bacteria, Gram-positive cocci and mycobacteria. Proteomics may be more helpful in identifying regulatory pathways. Proteomics covers thousand of proteins acting ... important to identify how and why several proteins are interrelated and interplay in regulatory and/or pathophysiological processes. This leads to the possibility of identifying critical...
Ngày tải lên: 12/08/2014, 19:22
Báo cáo y học: "Clinical review: Emergency department overcrowding and the potential impact on the critically il" pot
... [8]. Critically ill patients boarding in the ED are physically separated from the watchful eye of the intensivists who are ultimately responsible for their care. All of these factors could potentially lead ... care. Introduction Critical care begins immediately upon recognition of the critically ill (or potentially critically ill) patient, who has been defined as ‘any patient who is phy...
Ngày tải lên: 12/08/2014, 20:20
Báo cáo y học: " A retrospective quality assessment of pre-hospital emergency medical documentation in motor vehicle accidents in south-eastern Norway"
... University Hospital, Norway. 3 Department of Anaesthesiology, Akershus University Hospital, Oslo, Norway. 4 University of Oslo, Faculty Division Oslo University Hospital, Kirkeveien, Oslo, Norway. Authors’ ... our study only documented exact values of GCS and SBP in 48% and 53% of records, respectively. Exact RR was documented in 10% and RR RTS cate- gory in 54%. One cause of this d...
Ngày tải lên: 25/10/2012, 09:56
Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
... commonly complicated by hyperglycaemia caused by mediators of stress and inflammation. Severity of disease is the main risk factor for development of hyperglycaemia, but not all severely ill ... 14:R130 http://ccforum.com/content/14/4/R130 Page 4 of 8 underlying physiology, there is a combination of physio- logical factors predisposing a patient for hyperglycaemia in acute illness,...
Ngày tải lên: 25/10/2012, 10:02