Báo cáo y học: " Anchoring the genome" pps

... AT-islands has led to the emergence of a new class of drugs that specifically alkylate them [67]. These drugs exhibit an extraordinary cytotoxicity, which is likely to be due to their disruption of ... gene, the Chinese hamster dihydrofolate reductase β and β’ genes, the human β-globin gene, the chicken α-globin and lysozyme genes, and the Xenopus and mouse c-myc genes, function as...

Ngày tải lên: 14/08/2014, 08:20

... analyses and publication by the community would be unimpeded. We recognize the start of this 1-year period at approximately the time that this manuscript will be published, July 2011, and therefore ... period would end July 2012. Biological questions and types of analyses to be addressed by the python genome project Here we outline the major questions, types of analyses, and an...

Ngày tải lên: 09/08/2014, 23:20

... report on the 16th International Conference on Genome Informatics (GIW 2005), Yokohama, Japan, 19-21 December 2005. The conference on genome informatics held in Yokohama at the end of last year provided ... functional relatedness. By applying a threshold-based clustering algo- rithm to this network, numerous functional modules were obtained. The predicted modules were statistically an...

Ngày tải lên: 14/08/2014, 16:21

... contrary to widespread opinion, collaboration between industry and academia in proteomics is indeed fea- sible, despite the heterogeneity of the technology used and the complexity of the science. There ... to type-specific subpro- teomes such as the phosphoproteome (phosphorylated pro- teins), the glycoproteome (glycoproteins), the secretome (secreted proteins) and others. Antib...

Ngày tải lên: 14/08/2014, 15:20

... the Marlon Brando character in the movie &apos ;The Wild One'. For those of you not old enough to remember the thin, pre-Godfather Brando, virtually the same charac- ter type appears as the ... male lead in the musical 'Grease' (in the film of which, the part is played by John Travolta). 'Happy Days' ran for 11 years, far longer than its rather silly...

Ngày tải lên: 14/08/2014, 17:22

... presented by Pinay Kainth (University of Toronto, Canada), who tested the input contributions of all nonessential yeast transcription factors and their potential regulators on 27 cell-cycle- specific ... problem addressed by only few groups, including that of Jason Gertz (Washington University School of Medicine, St Louis, USA), who reported the use of libraries of synthetic regulatory re...

Ngày tải lên: 14/08/2014, 08:21

... for example for the lysozyme gene in myeloid cells [67], and for the b-globin gene in erythrocytes [68]. Priming by SWI/SNF complexes may even apply to the myogenic determination genes themselves. ... comparatively small fraction of the otherwise constitutively hypermethylated frog genome [18]. This hypomethylated state of the XmyoD gene may contribute to a short period of ubiquitou...

Ngày tải lên: 31/03/2014, 21:21

... rare frequency in the par ent popula tion may then have a higher fre- quenc y in the ne w population simply because one or mor e of the founders happened to carry the rare allele. If the new population ... or whether the Japanese mutation arose indepen- dently. In summary, this case illustrates the typical clinical manifestations of hyper-IgM syndrome due to AID deficiency, wh...

Ngày tải lên: 08/08/2014, 21:20

Ngày tải lên: 09/08/2014, 10:21

Ngày tải lên: 09/08/2014, 14:22