Báo cáo y học: "Determining promoter location based on DNA structure first-principles calculations" ppsx

... boundary conditions and Ewald summations [45]. Simulations were carried out using SHAKE [46] on all bonds connecting hydrogens and 2 fts time steps for integration of Newton equations of motions. ... possibility of using a well-defined physically based description of DNA deformability [36] derived from atomic simulations to deter- mine promoter location. Parameters describing the sti...

Ngày tải lên: 14/08/2014, 08:20

... dimroth@micro.biol.ethz.ch Abbreviations: DCCD, dicyclohexylcarbodiimide; POPC, 1-palmitoyl- 2-oleyl-sn-glycero-3-phosphocholine; ACMA, 9-amino-6-chloro- 2-methoxyacridine; SLPC, 1-palmitoyl-2-stearoyl-(n-doxyl)-sn-glyc- ero-3-phosphocholine; ... the ATP synthase extracted with Triton X- 100 and purified by fractionated precipitation with polyethyleneglycol. The enzyme was obtained in % 50% yi...

Ngày tải lên: 08/03/2014, 09:20

... LAR. Thirdly, let us analyze energy consumption in WSNHA. Energy consumption of transmitting and receiving packets is the main energy consumption in WSNHA. Packets can be divided into two types. One ... air-conditioners. HA control functions are usually embedded in the actuators. Actuator nodes generally have fixed locations and are powered by a main electricity supply. Controllers are used to...

Ngày tải lên: 21/06/2014, 05:20

... other diplotype configurations (P = 0.017, Mann-Whitney U test). We confirmed that the frequency of the diplotype configuration of S01/S01 was significantly higher in AOSD patients than in healthy control ... statistically among the diplotype configura- tions in the patients with polyarthritis and oligoarthritis. Discussion The present study has demonstrated a strong association between the h...

Ngày tải lên: 09/08/2014, 07:20

... JT, Park GS, Keystone EC, Paulus HE, Western Consortium of Practicing Rheumatologists: Evaluation of the preliminary definitions of minimal disease activity and remission in an early seropositive rheumatoid ... (RA) treatment is remission. The combination of new potent treatments, early intervention, and a treatment strategy of tight control makes remission a daily possibility [1-3]. In clini...

Ngày tải lên: 09/08/2014, 14:22

... from all exons of any transcript (based on UCSC known genes [13] or Ensembl [14]). A read is counted towards a ny gene that contains the aligned positions, possibly split by a junction, on either strand ... file 1). Locally constitutive means that, based on the under- lying annotation, all transcripts flanking that intron con- tain those exons (Figure S5 in Additional file 1). As wi...

Ngày tải lên: 09/08/2014, 23:20

... methods, 492 by any three methods and 1,130 by any two methods; 119 were identified only with Agilent SureSelect, 619 only with SureSelect 50 Mb, 149 only with NimbleGen SeqCap and 579 only with SeqCap ... of 50.71%). These regions also had a higher GC content than the regions that were captured poorly by Nimble- Gen and reasonably well by Agilent (the GC content in the regions was, respectiv...

Ngày tải lên: 09/08/2014, 23:20

... obtained by Easy CD4 assay (Guava) and flow cytom- etry. Bland-Altman plot comparing absolute CD4 cell counts estimated by Guava EasyCD4 assay and conventional flowcy- tometry. The dark continuous ... Absolute Lymphocyte Count (ALC) from the other analyzer as in dual platform system used in conventional flow cytometry. The CD4+ T cell counts estimated by EasyCD4 System showed high correlati...

Ngày tải lên: 10/08/2014, 05:20

... ≤ 1 day delay between blood col- lection and testing. These observations suggest that trans- port time may not have caused significant inaccuracy in our laboratory test results. Secondly, the ... – based criteria can only be answered by conducting clinical trials, this study has again demonstrated that TLCs are useful proxy measures for CD4 cell counts in determining ART eligibility. Acknow...

Ngày tải lên: 10/08/2014, 05:20

... Human Anatomy and Physiology, University of Padova, Italy. 2 Department of Neuroscience, University of Padova, Italy. 3 Department of Pharmaceutical Sciences, University of Parma, Italy. 4 Department ... English language correction and Italian Ministry of University and Scientific Research and the Fondazione Cariparma (Cassa di Risparmio di Parma, Italy) for funding contributions to the proje...

Ngày tải lên: 12/08/2014, 02:20