Báo cáo y học: " Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes" pot

... TCTACCGCTGCGAGGT GAT TGTAATGGAACACGAT GCCTTT Versican VCAN NM_004385.4 GCCTTTCCTATCACCTC GAGAA CACGGCAACCCAAAAT GACT Collagen, type II, alpha 1 COL 2A1 NM_001844.4 GGAAGAGTGGAGACT ACTGGATTGAC TCCATGTTGCAGAAAA CCTTCA Synaptosomal ... sialoprotein IBSP NM_174084.2 GACAGCTATGATGGTC AAGATTACTACA TGGGTGAACTCATCCC AGTCT Tenomodulin TNMD NM_001099948.1 TCTGGCGTGACGGGTC TT AAAAAAGGCATTGAA CAAAACGA...

Ngày tải lên: 12/08/2014, 11:23

... pulposus in young animals, including humans [2,4]. It has also been proposed that most of these cells gradually disappear during aging [2,4] and are replaced by endplate chondrocytes or inner annulus ... Research &  erapy, Minogue and colleagues [1] used transcriptional profi ling to examine the phenotypic characteristics of bovine intervertebral disc cells and provi...

Ngày tải lên: 12/08/2014, 12:20

... Rhodes DR, Yu J, Shanker K, Deshpande N, Varambally R, Ghosh D, Barrette T, Pandey A, Chinnaiyan AM: ONCOMINE: a cancer microarray database and integrated data-mining platform. Neoplasia 2004, 6:1-6. 56. ... Peltola M, Autio R, Neal D, Wasylyk B, et al.: Integrated DNA/RNA micro- array profiling of hormone-refractory clinical prostate can- cers and metastases indicates deregulation...

Ngày tải lên: 14/08/2014, 08:20

... (5'-TGCAGTC- GAATAAAACGCAGATATGTTCG-3') and MnSOD2R (5'- TTAACCATGGTTAAATAATCGGCGTTGAA-3'). Both prod- ucts were generated using pfu DNA polymerase (Stratagene, San Diego, CA, USA). Products ... MnSOD-1 was generated using primers Mn1F (5'GTCGAATAAAACGCAGATATGTTCG-3') and Mn1R (5'- CCATGGTTAAATAATCGGCGTTGAA-3'). MnSOD-2 was generated using primers M...

Ngày tải lên: 14/08/2014, 08:20

... a spot and array level. Spots ideally have a diameter of 100 μm. Diameters less than 70 μm and greater than 140 μm are indicative of scratches and printing problems and the corresponding data ... of genes, and presumably also responses to environmental toxicants, can vary dramatically between indi- viduals. In a systematic study of variation in gene expression in...

Ngày tải lên: 14/08/2014, 08:20

... in analytical scale. The four oligosaccharide fractions were separately pyridylaminated and designated endoH-PA, PNGaseF-PA, PNGaseA-PA and Hyd(HFA)-PA, respect- ively. Analytical anion-exchange ... Sigma (Deisenhofen, Germany). Peptide-N 4 -(N-acetyl-b-glucosaminyl)asparagine amidase A from almond (PNGase A) was from Seikagaku (Tokyo, Japan) and b-galactosidase from jack beans was...

Ngày tải lên: 31/03/2014, 08:20

... were as follows: 1. IL-4, CCAGCTAGTTGTCATCCTGCTCTTCTTTCTCG and CAGTGATGAGGACTTGGACTCATTCATGGTGC. 2. TGF-β1, TGGACCGCAACAACGCCATCTATGA- GAAAACC and TGGAGCTGAAGCAATAGTTGGTATC- CAGGGCT. 3. β-actin, ... obtained from the Shizuoka Laboratory Animal Center (Hamamatsu, Shizuoka, Japan). All mice were maintained in a pathogen-free facility at the Hyogo College of Medicine (Nishinomiya, Hyog...

Ngày tải lên: 09/08/2014, 08:22

... Max MB: Use of the cumulative propor- tion of responders analysis graph to present pain data over a range of cut-off points: making clinical trial data more understandable. J Pain Symptom Manage ... to at least 90%. The numbers and per- centages of patients achieving, say, at least 50% pain relief from baseline, might be defined as a responder, and presenta- tion of data in...

Ngày tải lên: 09/08/2014, 10:23

... analysis of cartilage repair by synovial mesenchymal stem cell transplantation in rabbitsIn vivo analysis of cartilage repair by synovial mesenchymal stem cell transplantation in rabbits. (a) ... defects. Mesenchymal stem cells (MSCs) are an attractive cell source for cartilage regenerative medicine because they can be har- vested in a minimally invasive manner, are easily isolat...

Ngày tải lên: 09/08/2014, 10:23

... hemoglobin, alkaline phosphatase, body mass index and the DAS28-3, the HAQ score and the Larsen score at baseline. Bivariate analysis was performed with all factors and covari- ates, and then backward stepwise ... Gerards AH, Landewe RB, Prins AP, Bruyn GA, Goei The HS, Laan RF, Dijkmans BA: Cyclosporin A monotherapy versus cyclosporin A and methotrexate combination therapy in...

Ngày tải lên: 09/08/2014, 13:22