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Báo cáo y học: " Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa" docx

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Báo cáo y học: " Non-syndromic multiple supernumerary teeth in a family unit with a normal karyotype: case report"

... Publisher. All rights reserved Case Report Non-syndromic multiple supernumerary teeth in a family unit with a normal karyotype: case report Francesco Inchingolo1, Marco Tatullo2, Fabio M. Abenavoli3, ... represents a rare form of hyperdontia, with bilateral multiple super-numerary teeth, with evident penetrance of the phenotype in the family unit engaged in the present study. The karyotype determination ... “mesiodens”, anamnestically deter-mined a familial predisposition in 31% of cases6. Su-pernumerary teeth are frequently found in the supe-rior maxillary bone and mainly in the premaxilla (90-98%)...
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Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx

Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx

... 2002 Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field Lucilia Pereira-Mourie`s1, Maria-Jose´Almeida1,3, ... Amino acid compositions (mole percent) of the water -soluble matrix, water-insoluble matrix, the EDTA -soluble matrix and the EDTA-insoluble matrix of Pinctada maxima nacre. Results are expressed as ... WSM.Glycosaminoglycan analysisGlycosaminoglycans are highly negatively charged because of the presence of sulfate ester and/or carboxyl groups.Therefore, they interact with cations and are precipitated...
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Báo cáo Y học: Human bile salt-stimulated lipase has a high frequency of size variation due to a hypervariable region in exon 11 pot

Báo cáo Y học: Human bile salt-stimulated lipase has a high frequency of size variation due to a hypervariable region in exon 11 pot

... Human bile salt-stimulated lipase has a high frequency of size variation due to a hypervariable region in exon 11 Susanne Lindquist1, Lars BlaÈ ckberg2and Olle Hernell1Departments of 1Clinical ... protein is, however,abundantly glycosylated and the apparent molecular masson SDS/PAGE has been estimated to 120±140 kDa [11, 12]. Human BSSL has a unique primary structure ascompared to other ... fetal pancreas and in pancreatic tumoralcell lines [35,36]. FAPP and BSSL are structurally closelyrelated, but are distinguished by a monoclonal antibodydirected towards a fucosylated epitope,...
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Báo cáo y học: "Erythropoietic Protoporphyria Masquerading as Angioedema in a 4-Year-Old Female" docx

... ArticleErythropoietic Protoporphyria Masquerading as Angioedema in a 4-Year-Old FemaleHelen C. Wang, MD; Ejaz Yousef, MDAbstract Angioedema is a common presentation with a broad differential, including rare ... 20 Angioedema is a common presenting symptomamong allergy practices. Angioedema is caused byincreased vascular permeability in the subcuta-neous tissue of the skin and respiratory and gas-trointestinal ... which anallergist must be familiar. Our objective was to report a case of swelling of the hands and feet mimick-ing angioedema with hepatomegaly in a 4-year-old girl. The patient was evaluated...
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Báo cáo y học: "Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1β" docx

... capacity todrive the key pathways typically associated with the pathogen-esis of OA. As shown here, as well as by others, IL-1 abruptlyshifts the metabolism of the chondrocyte stimulating the expression ... Given the breadth of chondroprotection provided by glucosamine as shown here, itis likely that these signaling pathways also are functionallyblocked by glucosamine. In light of the capacity of glucosamine ... con-sider cytokines, such as IL-1, as well other inflammatory medi-ators synthesized locally by synovial cells and chondrocytes, to be key contributors to the progression of the disease [3,4].The...
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Báo cáo y học: "ITGAV polymorphism and disease susceptibility in a Japanese rheumatoid arthritis population" ppsx

... Inoue E, Toyama Y, Hara M, Yamanaka H,Tomatsu T, Momohara S, Kamatani N: Failure to confirm associ-ation between PDCD1 polymorphisms and rheumatoid arthri-tis in a Japanese population. J Hum Genet ... with rheumatoid arthritis in the European Caucasian population: a family-based study. Arthritis Res Ther 2007, 9:R63.2. Friedlander M, Brooks PC, Shaffer RW, Kincaid CM, Varner JA,Cheresh DA: ... S, Alibert O, Quillet P,et al.: Dense genome-wide linkage analysis of rheumatoid arthritis, including covariates. Arthritis Rheum 2004, 50:2757-2765.5. Iwamoto T, Ikari K, Inoue E, Toyama Y, ...
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Báo cáo y học: "Catechol-O-methyltransferase gene haplotypes in Mexican and Spanish patients with fibromyalgia" docx

... 'sympathetically maintained pain'[5].Naturally occurring sympathetic neurotransmitters are cate-cholamines known as norepinephrine, epinephrine, and dopamine. All three substances act within the ... frequentCOMT gene haplotypes strongly associated with sensitivity toexperimental pain and induction of a more defective COMTenzyme. Healthy females with the 'high pain sensitivity haplo-type' ... associated with greater sensitivity to pain. Allthe individuals in the study were female. Fifty-seven Mexican patients and 78 Spanish patients were compared with theirrespective healthy control...
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Báo cáo y học: "The renal metallothionein expression profile is altered in human lupus nephriti" doc

... expression profile in systemic lupus erythematosuspatients with nephritis.IntroductionSystemic lupus erythematosus (SLE) is an immune-inflamma-tory disorder characterized by multiorgan involvement ... healthy kidneys and in lupus nephritisLocalization of metallothionein (MT) isoforms I + II in healthy kidneys and in lupus nephritis. Representative results of immunohistochemical analyses. ... MT-I+II-negative. (e) Lupus nephritis. Same findings as in (d). (f) Lupus nephritis. Some proximal tubules dis-play pronounced luminal MT-I+II staining in combination with MT-I+II depletion of the lining epithelial...
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Báo cáo y học: "Silencing CD36 gene expression results in the inhibition of latent-TGF-β1 activation and suppression of silica-induced lung fibrosis in the rat" pdf

... (StageI) and tiny collagen fibers in the lung of rats in the sil-ica+Lv-shCD36 group. Compared to the silica and the sil-ica+Lv-shCD36-NC groups, the number of nodules in the lungs of rats in the ... silencing expression of CD36 inhib-its activation of L-TGF-β1, which results in reducedhydroxyproline, collagen synthesis, and further preven-tion of the development of lung fibrosis. These ... expression results in the inhibition of latent-TGF-β1 activation and suppression of silica-induced lung fibrosis in the ratXin Wang, Ying Chen, Lina Lv and Jie Chen*Address: Division of Pneumoconiosis,...
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Báo cáo y học: "Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor necrosis factor-alpha antagonis" ppsx

... Copyedited and fully formatted PDF and full text (HTML) versions will be made available soon.Kinematic and dynamic gait compensations in a rat model of lumbar radiculopathy and the effects of tumor ... early stages of lumbar radiculopathy in the rat, and that, gait metrics and dynamics may be valuable measures in pre-clinical studies evaluating drug effectiveness. Abbreviations ANOVA: ... percentage stance times of 0 and a gait symmetry variable of approximately 0.5. A shift in either of these variables would indicate a shift away from balanced, symmetric gait. For the statistical...
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Báo cáo y học: " Local therapy with CpG motifs in a murine model of allergic airway inflammation in IFN-β knock-out mice" doc

... Interferon-betaprevents antigen-induced bronchial inflammation and air-way hyperreactivity in mice. Pharmacology 1997, 55:32-43.18. Satoh Y, Kasama K, Kuwabara M, Yimin, Diao HY, Nakajima H,Kohanawa M, Minagawa ... citation purposes)Respiratory ResearchOpen AccessResearch Local therapy with CpG motifs in a murine model of allergic airway inflammation in IFN-β knock-out miceVictor Matheu*1,2, Alexandra ... dose of intranasal CpG- ODN showed similar resultsThe percentage of local eosinophils in airways wasincreased after immunization and challenge with OVA in BALF of WT and IFN-β- /- compared to...
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Báo cáo y học: "Cellular infiltrates and injury evaluation in a rat model of warm pulmonary ischemia–reperfusion" pot

... identical pattern of alveolar oedema in a function of time by using a histological examination (H&E) and assessment by wet : dry ratio. An important increase of alveo-lar oedema was observed after ... of reperfusion in a model of acutelung injury, which was defined by quantifying apoptosis and alveolar oedema.Materials and methodsAnimalsMale inbred Wistar rats (mean weight 225 g), obtained ... delivertoxic radicals that damage pulmonary endothelium directly orindirectly by activating caspase-3, which results in apoptosis[1,2]. Second, they can damage pulmonary endothelium and parenchyma by delivering...
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Báo cáo y học: "Cell-specific microarray profiling experiments reveal a comprehensive picture of gene expression in the C. elegans nervous system" ppsx

... enrichedgenes from the larval pan-neural (LP), embryonic pan-neural(EP), larval A- class (LA), and embryonic A- class (EA) micro-array datasets. Additional data file 2 is a master annotationfile of ... dataset)(RMF, DMM, unpublished data). The top 50 enriched genes in this dataset were selected on the basis of statistical rank.RNA amplification and microarray data analysis A C. elegans Affymetrix ... was 1500041B16Rik,which did not have a summary graph; expression in the brain in this case was confirmed by direct visualization of the in situphotographs available in the Brain Atlas. C. elegans...
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Báo cáo y học: " Altered retinal microRNA expression profile in a mouse model of retinitis pigmentosa" docx

... is a table listing retinal miR expression data from Exiqon microarray analysis.Additional data file 2 is a table listing retinal miR expression data from Ambion microarray analysis. Additional ... data file 3is a table listing highly ranked retinal miR target genes pre-dicted using miRanda.The miRNA array data are available at Array Express [58]using accession numbers E-TABM-329 and ... forfurther analysis.Data availabilityMicroarray data from the above studies are available at thepublic database Array Express [58] using the following acces-sion numbers: E-TABM-329 (miRNA expression...
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Báo cáo y học: "Tandem repeat copy-number variation in protein-coding regions of human genes" docx

... (218/13,749) of proteins investigated carrying detectable polymorphisms in the copy-number of protein-coding tandem repeats. We found no evidence that tandem repeat copy-number polymorphism wassignificantly ... likely to contain tandem repeat copy-number polymorphisms within coding regions; these were prevalent among protein-bind-ing proteins.</p>AbstractBackground: Tandem repeat variation in protein-coding ... approximately1 in 5,000 transcripts in dinucleotide tandem repeats [48]: in our survey of 5,304 sequences containing 8,449 dinucleotiderepeats, we found an incidence of 36 frameshifting dinucle-otide...
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