Báo cáo y học: "The determinants of gene order conservation in yeasts" pdf

... Together, these data indicate that the helix breaker in cleavable signal sequences prevents recognition by SRP and is thereby, together with the hydrophobicity of the signal sequence, a determinant ... H.C. & Bernstein, H.D. (2001) The targeting pathway of Escherichia coli presecretory and integral membrane proteins is specified by the hydrophobici...

Ngày tải lên: 08/03/2014, 09:20

... Brissos et al.: The importance of measuring psychosocial functioning in schizophrenia. Annals of General Psychiatry 2011 10:18. Brissos et al. Annals of General Psychiatry 2011, 10:18 http://www.annals-general-psychiatry.com/content/10/1/18 Page ... and terminol- ogy and considers the relationship between soci al func- tioning, psychopathology and cognition. Psychosocial fu...

Ngày tải lên: 09/08/2014, 01:21

... years have witnessed the emergence of a new paradigm in the treatment strategy for RA, involving early Commentary The value of sensitive imaging modalities in rheumatoid arthritis Peter C Taylor The ... joints permit an increasingly refined analysis of anatomic detail. However, further research using these sensitive imaging technologies is required to delineate patho...

Ngày tải lên: 09/08/2014, 01:23

... 2 Research article The role of regulatory T cells in antigen-induced arthritis: aggravation of arthritis after depletion and amelioration after transfer of CD4 + CD25 + T cells Oliver Frey 1 , Peter ... With this in mind, it could be interesting to investigate whether the accumu- lated T reg cells in patients with arthritis function properly...

Ngày tải lên: 09/08/2014, 06:22

... men and women in the change in lateral tibial plateau bone area. Table 2 Annual change and rate in tibial plateau bone area Crude analysis Adjusted analysis Annual change Total P Men Women P a Men ... Principal outcome meas- ures in analyses were annual change and annual percentage change of tibial plateau bone area. Change in this area was o...

Ngày tải lên: 09/08/2014, 06:22

... cells to undergo a Th1 to T-helper type 2 shift and increase the secretion of anti-inflammatory cytokines IL-10 and IL-4, while decreasing the secretion of proinflammatory cytokines TNFα and IL-1 ... most of the available information regarding the temporal cytokine profiles in arthritic LEW rats pertained to antigen nonspecific ex vivo cytokine secretion or to cytokine mRNA le...

Ngày tải lên: 09/08/2014, 14:22

... Access The importance of localizing pulmonary veins in atrial septal defect closure! Ahmad Ali Amirghofran 1 , Ashkan Karimi 2* , Gholam Hossein Ajami 3 and Alireza Rasekhi 4 Abstract An 8-year-old ... discovery of three additional anomalies, namely Interrupted Inferior Vena Cava (IIVC), Scimitar syndrome, and systemic arterial supply of the lung. Postoperatively these f...

Ngày tải lên: 10/08/2014, 09:21

... during influenza infection suggests that it may play an impor- tant role in immune signaling [101]. Deletion of TLR3 leads to downregulation of inflammatory cyt okine and chemokine production and ... confer hypersusceptibility, increased lung bacterial load, and deficient neutrophil recruitment [114,117-123]. Interestingly, MyD88 may play an essential role only during the ea...

Ngày tải lên: 11/08/2014, 03:20

... this article as: van’t Hof et al.: The effectiveness of problem solving therapy in deprived South African communities: results from a pilot study. BMC Psychiatry 2011 11:156. van’t Hof et al. ... translated into English, Xhosa and Afrikaans, the three official languages spoken in South Africa’s Western Cape Province. The accuracy of the translations w...

Ngày tải lên: 11/08/2014, 16:20

... Wnt signaling in adult lung causes lung cancer, fibrosis, and inflammation [109]. Hyperactivation of β-catenin, caused by mutations of β-catenin, APC, and axin in lung epithelium induces lung tumors ... W, Yamin M, Noda M, et al.: Pleiotrophin signals increased tyrosine phosphorylation of beta beta- catenin through inactivation of the intrinsic catalytic activity...

Ngày tải lên: 12/08/2014, 11:22

... model. Editorial The role of anti- αα -actinin antibodies in the pathogenesis and monitoring of lupus nephritis Pierre Youinou 1 and Chaim Putterman 2,3 1 Laboratory of Immunology, Brest University Medical ... strongly to α-actinin [12,13]. Moreover, an increase in serum anti-α-actinin antibodies in lupus patients was associated with a 2.5-fold increase in...

Ngày tải lên: 12/08/2014, 11:22

... When exposed to high toxicity, the majority of the cell popula- GPS treatment results in the cytoplasmic release of cyto-chrome CFigure 4 GPS treatment results in the cytoplasmic release of cytochrome ... analysis of Annexin V/PI-stained cells To determine the mode of cell death upon GPS treatment, cells were stained with AnnexinV/PI and analysed by flow c...

Ngày tải lên: 12/08/2014, 14:20

... timepoint. This could have resulted in decreased levels of phagocytosis due to the deficiency in the binding and opsonisation of the pneumococcus due to the lack of SP -D, but also could be due ... the appearance of pneumococci in the blood and in limiting their numbers in the bloodstream. SP -D binds and agglutinates S. pneumoniae in the presence o...

Ngày tải lên: 12/08/2014, 18:20

... of inversions Proportion of gene pairs still as neighbours Differences in intergene distanceFigure 2 Differences in intergene distance. Intergene distances of gene pairs currently in synteny ... predictors in our study as controls. In summary, this analysis confirms the relevance of several aspects of gene expression control and genetic linkage as predictors of sy...

Ngày tải lên: 14/08/2014, 08:20

... properly cited. The rarity of gene shuffling in conserved genes<p>The incidence of gene shuffling is estimated in conserved genes in 10 organisms from the three domains of life. Successful gene ... example, duplication of domains within a gene. In such a gene shuffling event, the parental genes may be either destroyed or pre- served [6]. Gene shuf...

Ngày tải lên: 14/08/2014, 14:21