Báo cáo y học: "n idea whose time has com" docx

... [11]. In fact, N-myc amplification is nearly exclusively observed in neuroblastoma. N-myc amplifica- tion results in high N-Myc protein levels that could perturb the finely tuned interplay of N-Myc ... be regulated by the myc gene family members using various assays [1,27], including crosslinking [28], and cDNA microarrays [29]. Myc/Max interactions play an important role in Myc...

Ngày tải lên: 31/03/2014, 23:20

... Central Page 1 of 6 (page number not for citation purposes) Annals of General Psychiatry Open Access Primary research N-terminal fragment of B-type natriuretic peptide (NT-proBNP), a marker of cardiac ... sudden cardiac death. The risk of electrical heart instability can be increased in path- ological myocardial tissue, as for example in myocardial hypertrophy an...

Ngày tải lên: 08/08/2014, 21:20

... research may benefit from further investigation of the perceived influ- ences of pursuing multiple goals over and above inten- tions and PBC. Content of perceived goal interference and facilitation between ... con- text of multiple behaviours and multiple goals pursued. To the best of our knowledge, none of the studies in sys- tematic reviews of tests of...

Ngày tải lên: 11/08/2014, 05:21

... combination vaccines: intradermal administration of isolated components for control of anthrax, botulism, plague and staphylococcal toxic shock Garry L Morefield 1 , Ralph F Tammariello 2 , Bret ... wild-type toxin [13]. Antibodies that pre- vent botulism are presumed to inhibit binding of the toxin to neurons and thereby impede entry of the toxin int...

Ngày tải lên: 11/08/2014, 10:23

... veloped an RT-PCR assay for alphavirus detection[13]. Pässler et al. developed a detecting assay for alphaviruses based on antibodies [14]. Lambert et al. developed an RT-PCR assay and Taqman RT-PCR ... transcriptase polymerase chain reaction assay for detecting western equine and eastern equine encephalitis viruses Xiaoping Kang, Yuchang Li, Hong Liu...

Ngày tải lên: 12/08/2014, 01:22

... N-(2-(4-(2,2-dimethylpropionyloxy)phenylsulfonylamino)benzoyl) aminoacetic acid N-(o-(p-pivaloyloxybenzene)sulfonylamino benzoyl)glycine (Calbiochem) IC 50 = 50 nM [39] Respiratory Research 2009, ... this study, we demonstrate that N-α-PGP and PGP are biomarkers for COPD and are generated by an enzymatic cascade involving MMP's and PE. PGP generation by COPD sputum is block...

Ngày tải lên: 12/08/2014, 14:20

... that are sensitive (early appearance) and specific (typical of organ injury). They must be easy to detect and measure (possibly at bedside); they must correlate with severity (offering accurate ... RIFLE classification of AKI with the validation of NGAL as an early marker of kidney injury. This innovative approach brings a new hope for a timely diagnosis of AKI and thus a timely institu...

Ngày tải lên: 13/08/2014, 08:20

... clinicians may have already inserted a PAC in patients that “needed” one, leaving only those patients less likely to benefit from PAC insertion to be enrolled in the clinical trial, a form of ... study lead to dramatic changes in clinical practice? The answer, strangely enough, may be no. Across a variety of disease states, PAC use is already undergoing precipitous de...

Ngày tải lên: 13/08/2014, 08:21

... would probably grant more clinically useful information to assess AKI. Letter Acute kidney injury: time to shift from creatinine to the estimated glomerular filtration rate? Giuseppe Lippi and ... because it is affected by the GFR and by factors independent of the GFR, including age, sex, race, body size, diet, certain drugs, and laboratory analytical methods [2]...

Ngày tải lên: 13/08/2014, 11:22

... pulmonary endothelial dysfunction typically seen in the presence of sepsis. Because the early phase of hyperdynamic circulation is typically followed by a late hypodynamic circulatory state in ... endothelial dysfunction differ in hyperdynamic and hypodynamic sepsis. One established technique to investigate pulmonary endothe- lial dysfunction is the measurement of bradykin...

Ngày tải lên: 13/08/2014, 16:21

... 2010 BioMed Central Ltd Activated partial thromboplastin time waveform analysis as speci c sepsis marker in cardiopulmonary bypass surgery Christian P Schneider*, Martin K Angele and Wolfgang ... routine activated partial thromboplastin time measurement. BPW analysis was originally intro- duced as a marker for disseminated intravascular coagula- tion. Su...

Ngày tải lên: 13/08/2014, 20:21

... poly[ADP-ribose] levels) was aggravated only during the early phase up to 12 hours, whereas clear-cut increases in NOS activity, NO metabolites, and subsequently cytokines occurred only later ... myocardium to catecholamines in a hyperdynamic, murine model of septic shock. Crit Care Med 2006, 34:307-313. doi:10.1186/cc9219 Cite this article as: Hauser B, Radermacher P: Right man, r...

Ngày tải lên: 13/08/2014, 21:21

Ngày tải lên: 14/08/2014, 07:21

... and are driven by it, are constantly and rapidly evolving. Some of Petsko’s criticisms are constructive, and should be noted by policy-makers. But one should not throw the baby out with the bathwater, ... struc- tures may be redundant (1,729 PSI structures are unique by the 30% sequence identity criterion) or even appear uninteresting at first sight, many are of the highest technical quality,...

Ngày tải lên: 14/08/2014, 08:20

... is properly cited. An Ambystoma mexicanum EST sequencing project: analysis of 17,352 expressed sequence tags from embryonic and regenerating blast-ema cDNA librariese<p>Our analysis reveals ... Issue 9, Article R67 Research An Ambystoma mexicanum EST sequencing project: analysis of 17,352 expressed sequence tags from embryonic...

Ngày tải lên: 14/08/2014, 14:21