Báo cáo y học: " Gene expression profiling of Hfe-/- liver and duodenum in mouse strains with differing susceptibilities to iron loading: identification of transcriptional regulatory targets of Hfe and potential hemochromatosis modifiers" pdf
Báo cáo y học: " Gene expression profiling of Hfe-/- liver and duodenum in mouse strains with differing susceptibilities to iron loading: identification of transcriptional regulatory targets of Hfe and potential hemochromatosis modifiers" pdf
... control of hepcidin expression [23], in the B6 strain. Finally, and worthy of notewithin the context of modifiers of iron loading severity, wild-type D2 mice have significantly lower expression of ... Hfe- deficient B6 and D2 mice (two inbred mouse strains with divergent iron loading severity in response to Hfe disruption), to clarify the mechanisms of Hfe action, and to identify potential modifier genes.Results: ... downregulated by Hfe deficiency in D2mice, and this mainly affects genes that are involved in thecatabolism of cholesterol into bile acids (Cyp7a1 and Cyp39a1).Circadian rhythm Hfe -/- mice of both strains...
- 16
- 367
- 0
Báo cáo y học: " Gene expression profiling of human prostate cancer stem cells reveals a pro-inflammatory phenotype and the importance of extracellular matrix interactions" pps
... genes by flow cytometry and immunocytochemistryFigure 4Validation of selected genes by flow cytometry and immunocytochemistry. (a) Flow cytometry analysis of prostate cancer cells co-stained with ... University of York, Heslington, York YO10 5DD, UK. §York Centre for Complex Systems Analysis, Department of Biology, University of York, York YO10 5YW, UK. ¶Department of Urology, York Hospital, ... GO, Gene Ontology; GSEA, gene set enrich-ment analysis; IGF, insulin-like growth factor; IGFBP, IGFbinding protein; IL, interleukin; JAK, Janus activated kinase;KEGG, Kyoto Encyclopedia of Genes...
- 13
- 682
- 0
Báo cáo y học: "Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammation" pps
... article Gene expression profiling in murine autoimmune arthritis during the initiation and progression of joint inflammationVyacheslav A Adarichev1, Csaba Vermes1, Anita Hanyecz1, Katalin ... extremely complexowing to the diversity of cell types involved in the pathology and the polygenic character of the autoimmune disease [1-5]. The overall picture of molecular interactions in aninflamed ... gene expression stud-ies. Animal models of RA can facilitate the interpretation of genome-wide gene expression by providing genetic and clinical homogeneity, and an opportunity to monitor theonset...
- 12
- 546
- 0
Báo cáo y học: "Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis" doc
... pH 7.0 and embedded in paraffin for histological and immunohisto-chemical analyses. Serial histological sections were stained with hematoxylin and eosin and analyzed by two observers(CG and IT) ... expression of 1,058 genes in a subset of four patients with positive syno-vial immunostaining for TNF-α. These genes were enriched in families of genes involved in inflammatory processes.Clinicians ... induced by several cytokines in FLSs,thereby suggesting a role for these cytokines in the resistance to TNF blockade in RA.ANOVA: analysis of variance; anti-CCP2 antibody: anti-citrullinated cyclic...
- 13
- 486
- 0
Báo cáo y học: "Gene expression profiling in circulating endothelial cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis that is modified by iloprost infusion" potx
... effects of iloprost in systemic sclerosis are only partiallyknown. We aimed at studying the gene expression profile of circulating endothelial cells and the effects of iloprostinfusion and gene expression ... lies in the high intra-assay reproducibility and thehigh precision in the detection of both CECs and EPCsdue to the gating strategy and to the presence of adump channel [39,40].Finally, since ... VEGF) in SScpatients with and without digital ulcers.Conclusions In this study we analyzed gene expression profiles of CECs and EPCs obtained from healthy subjects and from SSc patients with and...
- 15
- 407
- 0
báo cáo hóa học:" Gene expression profiling for molecular distinction and characterization of laser captured primary lung cancers" ppt
... stains and confirmed by immunohistochemical staining look-ing for pan-cytokeratin, cytokeratin 5 and 7, chrom-ogranin A, synaptophysin and tissue-transcripion-factor-1. For validation of the ... forprogression of cell cycle, the cyclines A2 and B2, cyclin-dependent kinase 4 and the cell division cycle 2 geneswere upregulated. In the group of genes involved in DNArepair, we found genes with key ... ↓calcium-binding 3 genes ↑ 4 genes ↓ 3 genes ↓ 4 genes ↓apoptosis 1 gene ↓ 3 genes ↑ 1 gene ↓unknown 7 genes ↑ 38 genes ↓ 28 genes ↑ 54 genes ↓ 26 genes ↑ 44 genes ↓Journal of Translational Medicine...
- 17
- 662
- 0
Báo cáo khoa học: "Gene expression profiling of human dermal fibroblasts exposed to bleomycin sulphate does not differentiate between radiation sensitive and control patients" pptx
... women entered in a prospectiverandomised trial of bre ast radiotherapy fractionation. Gene expression profiling of primary skin fibroblasts exposed in vitro to bleomycin sulphate and mock treated ... performing the Affymetrix Gene Arrays and for technicalsupport and advice and Henrik Edgren at Institute for Molecular Medicine,University of Helsinki, Finland for help with the Affymetrix gene normalisation. ... predictive testing ishere tested in an exploratory study.Materials and methodsPatients and assessment of late normal tissue injuryPatients with a history of early breast cancer treated with breast...
- 6
- 355
- 0
Báo cáo y học: "Digital expression profiling of novel diatom transcripts provides insight into their biological functions" doc
... Functional annotation of these transcripts providesinsights into expression patterns of genes involved in various metabolic and regulatory pathways and into theroles of novel genes with unknown functions. ... seen in the similar expression profiles of the NS, AA, and UA libraries, and the repr ogramming of diatom photosynthesis in response to iron limit ation [33] is reflected in the com-mon gene expression ... sensitivity to iron compared to other phyto-plankton [52]. The iron limited (FL) l ibrary wasdesigned to study genes expressed at low concentrations of iron [33].Diatoms also play a major role in...
- 19
- 457
- 0
Báo cáo y học: "Gene expression profiling reveals novel TGFβ targets in adult lung fibroblasts" docx
... TGFβ-responsive genes included potential key candidates in theregulation by TGFβ of lung tissue fibrosis and includedangiotensin II receptor type 1 (AGTR1), SMURF2, a gene involved in terminating TGFβ ... transcription and signalling, identifying a series of genes previouslyunknown to respond to TGFβ in lung fibroblasts. Theseincluded angiotensin II receptor 1, providing furtherinsights into links between ... SD) of angiotensin II receptor type 1 pro-tein expression in lung fibroblasts treated with TGFβ (4 ng/ml )with or without 1/2 hour pre-incubation with of one the following signalling inhibitors:...
- 12
- 306
- 0
Báo cáo y học: " Global expression profiling of theophylline response genes in macrophages: evidence of airway anti-inflammatory regulation" ppsx
... extensively in viral infection [27] and can induce the gene expressions of interferon and cytokine [28]. Interestingly, an over- expression of IRF-7 can trigger monocyte differentiationtowards ... 99:8921-8926.18. Tomita K, Chikumi H, Tokuyasu H, Yajima H, Hitsuda Y, Matsumoto Y, Sasaki T: Functional assay of NF-kappaB translocation intonuclei by laser scanning cytometry: inhibitory effect by dex-amethasone ... monocyte/macrophagebiology, especially in atherogenic and inflammatory proc-esses [29,30].Airway inflammation in asthma is regulated by a complexnetwork of cytokines. We found that the expressions of several cytokines...
- 12
- 237
- 0
Từ khóa: Nghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu tổ chức chạy tàu hàng cố định theo thời gian trên đường sắt việt namđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinChuong 2 nhận dạng rui roTăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015