Báo cáo y học: "All duplicates are not equal: the difference between small-scale and genome duplicatio" docx

... similarity. In this study the characteristics of genes (and the proteins that they specify), derived from small-scale and whole- genome duplication (small-scale duplicates [SSDs] and whole -genome duplicates ... divergence. Discussion Collectively, our results demonstrate that the differences between the two types of duplicate are not limited to the way in which...

Ngày tải lên: 14/08/2014, 08:20

... to DNA had been determined by x-ray crystallography, and computed the number of contacts between each base in the bound DNA and the protein. For each factor they assembled collections of sequences ... transcribed, and the availability of a wide range of genome sequences has greatly accelerated research to decipher the genomic regulatory code. Although they are only...

Ngày tải lên: 14/08/2014, 14:21

... pooled and lyophilized to yield with solid of purity exceeding 99% as assessed by HPLC analysis of the final m aterials. I dentity and purity of peptide was confirmed by mass spectrometry, utilizing ... Szewczuk 1 and Wojciech Bal 1,2 1 Faculty of Chemistry, University of Wroclaw, Poland; 2 Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland A comparat...

Ngày tải lên: 22/02/2014, 04:20

... regulation, probably due to the presence of binding sites for other transcription factor around the CArG box [14]. We have therefore assayed the activity of the SRF molecules on two differently regulated vertebrate ... for this possibility. These molecules contained the N-terminal region, including the MADS box and SRF- conserved region, from one species and the C-terminal r...

Ngày tải lên: 22/02/2014, 07:20

... polymorphisms in genes encoding the enzymes UGT2B7, CYP2C8 and ABCC2, associated with hepatotoxicity induced by the non-steroidal anti-inflammatory drug Diclofenac. SSyysstteemmss bbiioollooggyy ... infections are likely to have reduced host toxicity if they are targeted to factors where the parasite and host have different fragility coefficients. Furthermore, when considering d...

Ngày tải lên: 14/08/2014, 08:21

... regulates the growth and the phenotype of the cardiac myocyte; and raise the intriguing question of whether the altered levels or proper- ties of Na + /K + -ATPase, either drug-induced, or by the actions ... a-actin, and the a 3 subunit of Na + /K + -ATPase), stimulation of protein synthesis, and myocyte hypertrophy. The solid arrows indicate experimentally supported e...

Ngày tải lên: 24/03/2014, 00:21

... digitalized and enlarged so that the distance between the top of the membrane and the yp bands could be measured accurately. The antibody-stained band corresponds to the lowest yp band (yp3) on the Coomassie blue-stained ... Neb-ODAIF-1 1)9 (data not shown). As the bulk of the yps is synthesized in the female fat body and transported by the haemolymph to be tak...

Ngày tải lên: 24/03/2014, 03:21

... cells there and are regulated by PD-1 and its ligands. B7-H3 and B7x could control the interaction between effector T cells and the peripheral tissues. The different varieties of regulatory T cells ... cells that leave the secondary lymphoid organs and penetrate back into the inflamed tissues are further regulated by interactions between PD-1 and its ligands, esp...

Ngày tải lên: 09/08/2014, 01:24

... classes are adjacent on the genome within 1 kb. We then compared these adjacency counts to a random background, obtained by randomly per- muting the class labels while preserving the genomic loca- tions, ... cell sites are in the HighOc class, only 11% of the sites that are unique to CD4+ T cells are in HighOc and as much as 33% of the 7,428 sites shared by all four ce...

Ngày tải lên: 09/08/2014, 20:21

... mm, therefore the patient underwent resection of the aneurysm of the ascending aorta, imp lanta- tion of a Vascutek 30 mm prosthesis and a thrombendar- terectomy of the right subclavian artery. ... may be due to Takayasu’s disease, giant cell arteritis, spondylarthropathy, Behcet’s syndrome, relapsing poly- chondritis, Cogan’s syndrome, retroperitoneal fibrosis, ankylosing spondylit...

Ngày tải lên: 10/08/2014, 09:21