Báo cáo y học: "Genome-wide investigation reveals pathogen-specific and shared signatures in the response of Caenorhabditis elegans to infection" pot

... appears to be primarily involved in the maintenance of intestinal cell integrity; abrogation of erm-1 function by RNAi provokes distortion of the intestinal lumen in the adult animal [56]. In the ... domains of common response genes The response of C. elegans to infection by S. marcescens and P. aeruginosa involves predominantly genes expressed in the...

Ngày tải lên: 14/08/2014, 08:20

... nerv- ous system, musculature and the cardiovascular system are assumed to reflect adult physiology in many respects, includ- ing the response to toxicants. Younger embryonic stages are likely to have ... of neurons in the brain. In in situ hybridization experiments, strong elevation of thioredoxin-like mRNA levels in response to Cd and MeHg was also noticed...

Ngày tải lên: 14/08/2014, 08:20

... analysis and the writing of the manuscript. AB: participated in the protocol, data col- lection, standarization and realization of lung testing, interpretation and data analysis and writing of the ... saline is instilled into each nostril by pipette. After 10 seconds, during which the subject shakes their head softly from side to side, they bring their head forward...

Ngày tải lên: 12/08/2014, 14:20

... Simone †‡ , Randy Wax §¶ , Katherine G Craig** and Keith R Walley †† *Resident, Department of Medicine, University of Toronto, Canada † Resident, Division of Thoracic Surgery, University of Toronto, Canada ‡ Resident, ... catecholamines and their receptors, which in turn control vascular tone and organ perfusion [4]. Proinflammatory cytokines released in sepsis alter steroid...

Ngày tải lên: 12/08/2014, 18:21

... sepsis). Lutien and colleagues more recently used intravenous and enteral antibiotics (including amphotericin) to achieve decont- amination of the gastrointestinal tract for the purpose of pos- sibly decreasing ... Maastricht, The Netherlands 2 Trauma Surgeon and Intensivist, University Hospital Maastricht, The Netherlands 3 Fellow in Trauma and Surgical Critical Care,...

Ngày tải lên: 12/08/2014, 19:22

... pcrevM4-3xNLS into the NcoI -and XhoI digested pCMV/myc/cyto vector (Invitrogen), and inserting an NcoI flanked oligo encoding the overlapping NLS/NOS signal from the HTLV-1 Rex protein into the NcoI ... study, the M4 mutant was studied to clarifying why oligomer formation is essential for Rev activity by assessing the requirements for restora- tion of the activity of...

Ngày tải lên: 13/08/2014, 09:21

... inflammatory endotoxin model. Unlike humans, rodents are resistant to endotoxin, and use of the high doses of endotoxin necessary to produce hypotension and mortality in mice may lead to toxic effects ... Leukocyte adhesion, however, is not strictly necessary for increased protein leakage during endotoxemia. In a study of rats given endotoxin by continuous infusion, fuco...

Ngày tải lên: 13/08/2014, 10:20

... Switzerland 4 Department of Dynamical Systems and Mathematical Physics, Research Institute for Mathematics and Computing Science, University of Groningen, 9700 AK Groningen, the Netherlands 5 Information and System ... according to a ‘sliding scale’ protocol (a predetermined amount of insulin is administered according to the actual BG) or ‘dynamic’ protocol (the dosage o...

Ngày tải lên: 13/08/2014, 18:22

... l-lysine, l-serine, b-alanine, taurine, sarcosine, dimethylglycine, glycine betaine, trimethylamine N-oxide, and cytidine 2¢-3¢ cyclic monophosphate were also obtained from Sigma. These and other ... advances in understanding the effect of osmolytes on protein stability, folding and the activity of proteins and enzymes, the relationship between protein stabilization by osm...

Ngày tải lên: 07/03/2014, 00:20

... ways for estimating the inter- and intra-reuse. Cycles in the breakpoint graphs provide yet another way to estimate the inter- and intra-reuse. For a branch e =(P, Q) of the phylogenetic tree, one ... test’ was applied in numerous papers. The Nadeau-Taylor test typically amounted to constructing a histogram of synteny blocks and evaluating (often visually) whether...

Ngày tải lên: 09/08/2014, 22:23