Báo cáo y học: "Characterization of heterotypic interaction effects in vitro to deconvolute global gene expression profiles in cancer" ppt

... muscle actin (ACTA2), myosin regu- latory light chain interacting protein (MYLIP), myosin, light polypeptide kinase (MYL), myosin regulatory light chain 2, smooth muscle isoform (MYL9), calponin 2 ... charac- terize the effects of heterotypic cellular interaction, to gain insight into the underlying biology of these effects in normal mammary tissue and breast cancer. To isola...

Ngày tải lên: 14/08/2014, 08:20

... differences in costs of the TNF-blocking agents did not induce a selection bias. Also, the possibility for termination bias was investigated by examining disease activity of patients terminating therapy because ... predictor for a high level of adher- ence to therapy. On the other hand, the 1-year level of adher- ence to therapy found in our study closely resembles values foun...

Ngày tải lên: 09/08/2014, 08:23

... moderate 780 to 1480, high risk >1480]) had received imatinib 400 mg per day since the beginning of January 2004. After approximately 10 months of therapy, full hematologic and cytogenetic remission, then ... performed. In May 2007, the patient resumed imatinib at a daily dose of 600 mg per day. In July 2007, after approximately two months of therapy with imatinib, laboratory...

Ngày tải lên: 11/08/2014, 17:21

... of 8 dobutamine infusion (DOBU, starting at 7.5 μg/kg/min- ute and titrated to induce a 30 to 50% increase in con- tinuous CO); 5 minutes after stopping dobutamine infusion; after inducing hypovolemia ... Edwards); BASE, baseline; DOBU, dobutamine infusion; HYPO, hypovolemia induced by bleeding; HYPER, hypervolemia induced by volume loading; ALI, acute lung injury induced by oleic aci...

Ngày tải lên: 14/08/2014, 07:21

... characterization of pravastatin loaded erythrocytes Hematological Indices To determine the effect of loading process on erythrocytes, normal erythrocytes, erythrocytes sus- pended in PBS, and pravastatin-loaded ... amount of pravastatin entrapped in 0.1 ml of the final packed erythrocytes. Efficiency of entrapment The percentage of the loaded amount of pravas- tatin...

Ngày tải lên: 25/10/2012, 11:10

... difficulty in amplifying the sequences in these re- gions. In our study, we attempted to amplify each ex- tremity, but failed. Interestingly, phylogenetic analysis based on the NS1 gene revealed ... epitope. Furthermore, in 5 out of 6 isolates belonging to group 3, the amino acid at position 183 substi- tuted to alanine. Figure 1. Phylogram generated by neighbor-joi...

Ngày tải lên: 26/10/2012, 10:03

... decrease in the older population, suggesting a shortening of the sensory auditory memory trace with increasing age [19]. The same phenomenon occurs in the very young, indicating the necessity of ... interdisciplinary interest in its application as a prognostic, diagnostic, and investigative tool, an understanding of the underpinnings of P300 and N200 physiology may support...

Ngày tải lên: 02/11/2012, 11:08

... the C-terminus exerts its auto-inhibitory action, presumably by binding to an intramolecular site [1,23–27]; thus, it might ham- per the access of PPI1 588 His 6 . FC-induced binding of 14-3-3 ... therein). The auto-inhibitory action of the C-terminus is suppressed, besides by pH, by lysophospholipids and by 14-3-3 proteins ([1] and ref- erences therein). The latter are regulatory pro...

Ngày tải lên: 19/02/2014, 07:20

... are in line with the high GSH K m value obtained for SmGSTO and the strong inhibitory effect of S-hexyl glutathione on the enzyme activity. The preference of SmGSTO for more hydrophobic alkyl-bound ... activity was inhibited to different extents by classical GSTs inhibitors. In addition, GSTs’ substrate, CDNB, which inhibits thioredoxin activity, also inhibited GSTO activity. Our ph...

Ngày tải lên: 21/02/2014, 01:21

... determinants of cold-adaptation in psychrophilic enzymes. Glycine residues are highly con- served in the sequences of the proteinases compared in this study. For example, of the 37 glycines present ... protein. Thus an increased number of ÔflexibleÕ glycines in loops is not expected to play a key role in cold-adaptation of VPR. As for other subtilisin-like proteinases, ca...

Ngày tải lên: 21/02/2014, 01:21