Báo cáo y học: "DetectiV: visualization, normalization and significance testing for pathogen-detection microarray data" pot

... seen, bovine respira- tory syncytial virus and respiratory syncytial virus are second and third, respectively. Both respiratory syncytial virus and bovine respiratory syncytial virus have higher ... tool for analyzing pathogen-detection microarray datasets that allows simple visualisation, normalisation and significance testing. </p> Abstract DNA microarrays offer the p...

Ngày tải lên: 14/08/2014, 08:20

... extracellular ligand for conveying ligand specificity, a single pass transmembrane hydrophobic helix and a cytoplasmic portion containing a tyrosine kinase domain. The kinase domain has regulatory sequence ... EGFR. Hydrophobic pocket – though not used by ATP but plays an important role in inhibitor selectivity. c) Hydrophobic channel – not used by ATP and may be exploited for inh...

Ngày tải lên: 03/11/2012, 09:57

... other signaling pathways [44]. Deltex Notch is particularly important for T lymphocyte maturation and lineage commitment in the thymus [45]. In the periphery, the ligation of Notch by ligands Delta or ... and autoimmunity. Curr Opin Immunol 2003, 15:668-676. 86. Yokoi N, Komeda K, Wang HY, Yano H, Kitada K, Saitoh Y, Seino Y, Yasuda K, Serikawa T, Seino S: Cblb is a major susceptibili...

Ngày tải lên: 09/08/2014, 07:20

... searching for genes (for example, by symbol, identifier, location, sequence). Every gene portal also must make some effort at resolving syno- nyms that have been historically used in the literature. And every ... used symbol in the literature (for example, TP53 and P53). Finally, new online resources are continually being developed, and staying abreast of these tools and evaluatin...

Ngày tải lên: 09/08/2014, 20:21

... method was used for minimization with flexibility allowed only for those atoms within the 6 Å radius of every atom of the ligand for 150 runs. The topology and parameter files for the compounds ... Crystallography 2007, 40(3):598-599. 12. Lipinski CA, Lombardo F, Dominy BW, Feeney PJ: Experimental and computational approaches to estimate solubility and permeability in drug disco...

Ngày tải lên: 10/08/2014, 09:22

... Hospital, Ballykelly, Co Derry, Northern Ireland BT49 9HS, UK. 3 Department of Podiatric Surgery, Derbyshire County Primary Care Trust, Ilkeston Hospital, Heanor Road, Ilkeston Derbyshire DE7 8LN, ... MJ: Scarf osteotomy for hallux valgus. A prospective clinical and pedobarographic study. J Bone Joint Surgery 2004, 86-B:830-6. 11. Malviya A, Makwana N, Laing P: Scarf osteotomy for hallu...

Ngày tải lên: 10/08/2014, 21:24

... meta-analysis by Peyrin-Biroulet et al. demonstrate that anti-TN F therapy is safe and effec- tive for both luminal and FCD, in patients who are refractory to stand ard medical therapy. Due to ... detailed, analysi s elevated the results from the ACCENT II study on the safety and efficacy of infliximab in inducing and maintaining fistula closure [8]. T he CHARM t rial, and more re...

Ngày tải lên: 11/08/2014, 00:23

... Beam-Goulet J, Lysaker P, Cicchetti D: The positive and negative syndrome scale and the brief psychiatric rating scale: Reliability, comparability, and predictive validity. Journal of Nervous and Mental ... Multifamily Group Psychoeducation and Cognitive Remediation for First-Episode Psychosis: A Randomized Controlled Trial. BMC Psychiatry 2011 11:9. Submit your next manuscript to...

Ngày tải lên: 11/08/2014, 16:22

Ngày tải lên: 13/08/2014, 08:20

... antibacterial and antifungal therapy. Whether acyclovir prophylaxis or early treatment in cases suspicious for HSV-related tracheobronchitis or pneumonia in critically ill patients has the potential ... suspected outbreak situation, system- atic testing of respiratory samples for HSV was not performed for all patients. The outcome was therefore defined clinically (that is, presence...

Ngày tải lên: 13/08/2014, 10:20