Báo cáo y học: "PHIDIAS: a pathogen-host interaction data integration and analysis syste" pps

... parsed data into a pre-designed MySQL database system. Data from the KEGG pathway database are manually curated and added to Phinet. Phinet also includes a web-based data submission system that permits ... understand the intricate interactions between path- ogens and hosts, we have now developed a web-based PHI data integration and analysis system (PHIDIAS) that permit...

Ngày tải lên: 14/08/2014, 08:20

... http://arthritis-research.com/content/5/6/R310 R315 20. Fujikawa Y, Sabokbar A, Neale S, Athanasou NA: Human osteo- clast formation and bone resorption by monocytes and syn- ovial macrophages in rheumatoid arthritis. Ann Rheum Dis 1996, ... hypertrophy and hyperplasia of the synovial lining cells, pannus formation with articular cartilage erosion, and chronic infiltration of synoviu...

Ngày tải lên: 09/08/2014, 01:23

... in data models, data access methods and file formats. This leads to the incompat- ibility of data formats for the analysis of pathway data. To avoid this, data standards are adopted by many of the ... Keerthikumar S, Mathivanan S, Patankar N, Shafreen B, Renuse S, Pawar H, Ramachandra YL, Prasad TSK, Acharya PK, Ranganathan P, Chaerkady R, Pandey A: Human Proteinpedia: A unif...

Ngày tải lên: 09/08/2014, 20:21

... 2and 9. TNF -a F, 5′-CATCTTCTCAAAATTCGAGTGACAA; TNF -a R, 5′-TGGGAGTAGACAAGGTACAACCC; TNF -a P, 5′-CACGTCGTAGCAAACCACCAAGTG GA; IL-6F, Based on TaqMan produt No.4331348 IL-6R, Based on TaqMan produt ... P, 5′ -AAAACCTCCAACCTCACGGACAC CCA-3′ GAPDH F, 5′-TTCACCACCATGGAGAAGGC-3′; GAPDH R, 5′-GGCATGGACTGTGGTCATGA-3′; GAPDH P, 5′-TGCATCCTGCACCACCAACTGCT TAG-3′. The conditions f or the TaqMan P...

Ngày tải lên: 11/08/2014, 03:20

... factor, α1-antitrypsin) and nasal mucociliary clearance (meas- ured by the saccharin test and nasal nitric oxide measure- ment). No patient had a history of salt wasting or a familial history of respiratory ... subnormal respiratory function. None had a bronchial colonization by Pseudomonas aeruginosa. In patients from group 1, all but one had a normal or a very low basal nasal...

Ngày tải lên: 12/08/2014, 15:21

... Supplementary materials and methods. This table summarizes the clinical data of patients with RA, OA and AS. Additional file 2: Supplementary results. This table provides the raw microarray data to ... -GCCTCCA CTGTGCTCACTGA-3’;forwardprimerforhumanb- actin, 5’-TGGCACCCAGCACAATGAA-3’;andreverse primer for human b-actin, 5’-CTAAGTCATAGTCCGCC- TAGAAGCA-3’. Primer efficiency was determin...

Ngày tải lên: 12/08/2014, 17:22

... evolvability is also largely hidden when viewed from a reductionist lens. As already discussed, the (internal) organizational versatility afforded by degeneracy can allow many perturbations to have ... present an alternative conceptual model to account for these findings and to illustrate additional ways in which degeneracy may facilitate robustness and evolvability in complex adaptive...

Ngày tải lên: 13/08/2014, 16:20

... sepa- a) Schematic representation of the CYP 3A4 -, CYP 3A5 - and UGT-catalyzed metabolic pathway for MDZFigure 1 a) Schematic representation of the CYP 3A4 -, CYP 3A5 - and UGT-catalyzed metabolic pathway ... 2003, 31:938-944. 24. Tateishi T, Watanabe M, Moriya H, Yamaguchi S, Sato T, Kobayashi S: No ethnic difference between Caucasian and Japanese hepatic samples in the expression f...

Ngày tải lên: 13/08/2014, 16:21

... detected by comparative hybridization to a DNA microarray. Standard technical recommendations common to all microarray experiments (for example, the need for dye swaps) apply equally to ChIP-chip ... of raw data was not practical because of inability to automate all four analysis methods. (c) ROC curves comparing ChIPOTle, SAEM, and PeakFinder with respect to their ability to ident...

Ngày tải lên: 14/08/2014, 15:20

... H, Kayagaki N, Kuida K, Nakano H, Hayashi N, Takeda K, Matsui K, Kashiwamura S, Hada T, Akira S, et al: Caspase-1-independent, Fas/Fas ligand-mediated IL-18 secretion from macrophages causes acute ... degradation of extracellular matrix components and cytokines and also as a chemo- attractant for l eukocytes, including T cells. Cathepsin G has a potent elastolytic activity and thus...

Ngày tải lên: 11/08/2014, 06:22