... function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation Rowan S Hardy 1 , Andrew ... in regulating synovial inflammation. It is possible that this system is needed to counteract endogenous inflammatory regulators (such as macrophage migration inhibitory factor [41])...
Ngày tải lên: 09/08/2014, 08:22
... terminal enzyme of the respiratory chain in mitochondria and many prokaryotes. As an integral membrane protein it catalyzes the reduction of dioxygen to water using electrons from cytochrome c. Four ... for the protonated form can be seen concomitant with the reduced state at 1515 cm )1 and the mode typical for the deprotonated form at 1498 cm )1 , indicating the protonation of...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: Ligand-induced heterodimerization between the ligand binding domains of the Drosophila ecdysteroid receptor and ultraspiracle docx
... The primary purpose of this work is to address the possibility that EcR and USP are capable of dimerization in the absence of a bipartite EcRE and to monitor the potential influence of ecdysteroid ... determined by the two-hybrid assay and indicated by the appearance of basal (noninduced) b-galactosidase activity; + or – signs mean this activity to be significantly or unsi...
Ngày tải lên: 18/03/2014, 01:20
Báo cáo y học: "Improvement in symptoms and signs in the forefoot of patients with rheumatoid arthritis treated with anti-TNF therapy" ppsx
... effective way of reducing synovial hypertrophy and preventing erosions in patients who have rheumatoid arthritis (RA) [1,2]. Unfortunately studies to date have tended to focus on the hand joints and ... presence of synovial hypertrophy and synovitis in the 2 nd and 5 th metatarso-phalangeal (MTP) joints and plantar forefoot bursal hypertrophy before and 12 weeks after t...
Ngày tải lên: 10/08/2014, 21:24
Báo cáo y học: " Acid-base balance and hydration status following consumption of mineral-based alkaline bottled water" ppt
... assumed that AK water is being con- sumed at an average rate of 2.3 L/day (an average of rates from Table 4), and that at least a week of regular consumption is required for hydration and/ or pH ... Water Consumed 1 Pre-Treatment Placebo Water Placebo Water 2 Treatment Placebo Water AK Water 3 Treatment Placebo Water AK Water 4 Post-Treatment Placebo Water Placebo Water Note: Pla...
Ngày tải lên: 11/08/2014, 23:21
Báo cáo y học: " Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis" ppt
... stimulates proinflammatory factors in neutrophils and macrophages [21-23], these low concentrations may well play a proin- flammatory role in inflamed tissue. By using synovial cells of patients ... localization of HNP1-3 and HBD-2 and double immunofluorescence To study the localization of defensins, immunohis- tochemistry of the synovial lining and sublining area was perfor...
Ngày tải lên: 12/08/2014, 14:22
Báo cáo y học: "Geographical information system and access to HIV testing, treatment and prevention of mother-to-child transmission in conflict affected Northern Uganda" pot
... similar pattern of inadequacy at lower health facility levels. The results of the stock-outs of HIV test kits and drugs at lower health facilities reflect limited capacity of supply chain system ... Uganda WHO and UNICEF offices as well as material contributions from Uganda ministry of health, bureau of statistics and district health directors of the three study dist...
Ngày tải lên: 13/08/2014, 13:21
Báo cáo y học: "Violence against civilians and access to health care in North Kivu, Democratic Republic of Congo: three cross-sectional survey" docx
... trauma and mortality, as yet unrecorded. ThegeographicsituationofKabizomaybelinkedto the few reported deaths from violence. During the recall periodofthesurveytherelatively large town of Kabizo was ... paper; EG, YCL, and JP participated in the design of the study, analysis and interpretation of data, and revising the paper critically for substantial intellectual content; KC, LE...
Ngày tải lên: 13/08/2014, 14:20
Báo cáo y học: "Assessing food appeal and desire to eat: the effects of portion size & energy density" pptx
... sug- gests that desire to eat a food item could play a larger role in the dysregulation of weight status relative to the food’s preference. However, to date, the majority studies evaluating liking and ... differentiate between food appeal and desire to eat foods when assessing these ratings using the same type of metric. Additionally, relations among food appeal and desire...
Ngày tải lên: 14/08/2014, 08:20
Báo cáo y học: "Center for Biotechnology and Genomic Medicine, Medical College of Georgia" docx
... Modulation of tryptophan catabolism by regulatory T cells. Nat Immunol 2003, 4:1206-1212. 63. Cauley LS, Miller EE, Yen M, Swain SL: Superantigen-induced CD4 T cell tolerance mediated by myeloid ... Many of the upregulated mol- ecules have been implicated in immunosuppressive function. Most notably, many of the genes are related to IFN-γ and some belong to the TNF family receptors...
Ngày tải lên: 14/08/2014, 20:22