Báo cáo y học: " siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P3-mTOR signaling pathway as a primary regulator of transferrin uptak" docx
Báo cáo y học: " siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P3-mTOR signaling pathway as a primary regulator of transferrin uptak" docx
... 7, Article R142 Research siRNA screen of the human signaling proteome identifies the PtdIns(3,4,5)P 3 -mTOR signaling pathway as a primary regulator of transferrin uptake Thierry Galvez, Mary ... list of the genes targeted by the human d -siRNA signaling library. Additional data file 3 is the list of hits from the primary screen. Addition...
Ngày tải lên: 14/08/2014, 07:22
Báo cáo y học: "Part II, Provider perspectives: should patients be activated to request evidence-based medicine? a qualitative study of the VA project to implement diuretics (VAPID)" ppsx
... some they had problems with hypokalemia or renal issues that they were not a candidate for the medication and, uh, my patients are diabetic, they have coronary artery disease, they have, you know, metabolic ... ‘on a certain date the blood pr essure had been high,’ and that date had been like on a specialty care visit, so it was a number that I probably wasn’t awareof becausemaybe...
Ngày tải lên: 11/08/2014, 05:21
Báo cáo y học: "(Sub)clinical cardiovascular disease is associated with increased bone loss and fracture risk; a systematic review of the association between cardiovascular disease and osteoporosis" ppsx
... Ichikawa S, Kasama S, Takahashi T, Sakamoto H, Kumakura H, Takayama Y, Kanda T, Murakami M, Kurabayashi M: Relationship between brachial arterial endothelial function and lumbar spine bone mineral density ... Sumino H, Ichikawa S, Kasama S, Takahashi T, Kumakura H, Takayama Y, Kanda T, Sakamaki T, Kurabayashi M: Elevated arterial stiffness in postmenopausal women with osteoporosis. Maturit...
Ngày tải lên: 12/08/2014, 15:22
Báo cáo y học: "Early drotrecogin alpha (activated) administration in severe sepsis is associated with lower mortality: a retrospective analysis of the Canadian ENHANCE cohort" ppsx
... Nevertheless, because delays in therapy with DrotAA are associated with increased mortality, we believe that the concept of apparent clinical stability as a guide to the aggres- siveness of therapy for ... and Eli Lilly. HNF is an employee of Eli Lilly Canada and BL was an employee of Eli Lilly Canada at the time of the research and manuscript preparation. HNF holds shar...
Ngày tải lên: 13/08/2014, 16:20
Báo cáo y học: "MMP-3 expression and release by rheumatoid arthritis fibroblast-like synoviocytes induced with a bacterial ligand of integrin α5β" pdf
... in the syno- vial tissue of patients with advanced rheumatoid arthritis or osteoarthritis: analysis with gas chromatography-mass spec- trometry and pan-bacterial polymerase chain reaction. Arthritis Rheum ... (ImageQuant, Molecular Dynamics, Sunnyvale, CA, USA), spots were quantified using the AtlasImage 2.0 Software (Clontech), developed specifically for analysis of the Atlas cDNA...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Platelet-derived exosomes induce endothelial cell apoptosis through peroxynitrite generation: experimental evidence for a novel mechanism of septic vascular dysfunction" pot
... endocytosed, or they could merely attach to the cell surface, modifying transmem- brane signaling pathways. Endothelial activation is physiologically important in the con- text of the inflammatory ... Thus, in accordance with the activation of NO synthases and with the cytosolic redox balance of the individual cell type in a given physiological scenario, NO may either fu...
Ngày tải lên: 13/08/2014, 08:20
Báo cáo y học: "Does switching from oral extended-release methylphenidate to the methylphenidate transdermal system affect health-related quality-of-life and medication satisfaction for children with attention-deficit/hyperactivity disorder&
... call to caregiv- ers at 30 ± 3 days after the last dose of study medication to assess any new or ongoing AEs. Health-related quality of life and medication satisfaction measures As secondary ... to assess the impact of ADHD symptoms on the lives of children and their families at baseline and study endpoint. Satisfaction with MTS use was assessed via a Medication Satisfactio...
Ngày tải lên: 25/10/2012, 10:06
Báo cáo y học: "Grb2-associated binder 1 polymorphism was associated with the risk of Helicobactor pylori infection and gastric atrophy"
... However, the Gab1 polymorphism did not influence the development of gastric cancer. The Gab1 A/ A decreased the risk of H. pylori seropositivity, whereas the Gab1 G /A+ A /A was associated with gastric ... GTT CCC, R1: 5’ ACA CAA TTT AGT AAT AGC CAA AGT CAA C, F2: 5’ GTT GTT GTG AAG TAG AAA CTG ATT TCT AA, and R2: 5’ CTG GGG AGT GGG CCA. Genomic DNA was applied in a v...
Ngày tải lên: 31/10/2012, 15:37
Tài liệu Báo cáo Y học: Bivalent cations and amino-acid composition contribute to the thermostability of Bacillus licheniformis xylose isomerase doc
... Structural distribution of stability in a thermophilic enzyme. Proc. Natl Acad. Sci. USA 96, 13674–13678. 3. Hasegawa, J., Uchiyama, S., Tanimoto, Y. , Mizutani, M., Kobayashi, Y. , Sambongi, Y. & ... [39,40]. The E a values of BLXI inactivation were calculated for the apoenzyme in the presence and absence of metals (Table 3). The nature of the metal present clear...
Ngày tải lên: 22/02/2014, 07:20
Báo cáo Y học: Cellular stresses profoundly inhibit protein synthesis and modulate the states of phosphorylation of multiple translation factors potx
... to the cell stresses tested here. Sorbitol is known to activate the p38 MAP kinase a/ b pathway in other cell types [59]. As assessed by measuring the activity of the downstream kinase, MAPKAP-K2 ... examined. For example, there was no loss of cellular material as assessed by the protein content of the resulting lysates (data not shown). To assess cell viability more...
Ngày tải lên: 18/03/2014, 01:20