Báo cáo y học: "Bias in phylogenetic tree reconciliation methods: implications for vertebrate genome evolution" pdf

... commensurately increased confidence in any topology - each individual gene tree can only be inferred from the gene family it represents. For this reason, some methods for carrying out the reconciliation explicitly ... tree inference are strongly influenced by the par- ticular information contained within the protein sequences of the genes being considered, reconciliation of any...

Ngày tải lên: 14/08/2014, 07:22

... more closely. Conclusion RNAi has rapidly evolved as a potent technology for the analysis of gene function in many organisms in vitro and in vivo. In mammals, at present RNAi is mainly restricted ... Q, McManus MT, Nguyen T, Shen CH, Sharp PA, Eisen HN, Chen J: RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibit- ing all...

Ngày tải lên: 09/08/2014, 01:23

... Shortino D, Crow JW: A comparison of continuous intravenous epoprostenol (prostacyclin) with conventional therapy for primary pulmonary hypertension. The Primary Pulmonary Hypertension Study Group. ... meta-analysis by separately analyzing individual classes of PAH treat- ment, by including data only f or approved medication doses, and by expanding the search to captu re studies published...

Ngày tải lên: 12/08/2014, 11:20

... ward with sepsis in an effort to predict bacteremia using high-mobility group-box protein 1, lipopolysaccharide-binding protein and procalcitonin [21]. The study included information on 154 subjects ... High-mobility group-box protein 1 is a mediator of later inflammatory events in sepsis, and may be a target for therapeutic intervention [16-18]. Lipopolysac- charide-binding protein is...

Ngày tải lên: 13/08/2014, 11:22

... mirrored. GB Editorial Team Genome Biology 2011, 12:402 http://genomebiology.com/2011/12/3/402 Page 2 of 3 e National Center for Biotechnology Information (NCBI) in the US recently announced that, as ... the University of Maryland, Mark Gerstein (MG) from Yale University and Rob Knight (RK) from the University of Colorado). 1. Why did the SRA close? How widely used by the communit...

Ngày tải lên: 09/08/2014, 22:23

... focus group. Initially, phase C focus group transcripts with accom- panying field notes will be independently analyzed by the study leads for each province. Study leads and HF team members will then jointly ... adequately described, those reading the findings will be able to make decisions about the transferability of the findings of this study to other settings. Dependability is assured by...

Ngày tải lên: 10/08/2014, 10:23

... visibility by ensuring proper indexing and tracking. The Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine (SJTREM) is a peer-reviewed interna- tional journal indexed in PubMed, ... Sco- pus, and Google Scholar. In addition, SJTREM has recently been accepted for indexing by MEDLINE. Deci- sions on tracking in EMBASE and by Thomson Reuters will occur shortly. The Jou...

Ngày tải lên: 13/08/2014, 23:21

... exhibiting the greatest transition frequency in the genome [38] (Figure 4c). Naturally, this is also in agreement with both hypotheses, namely DUS arising by point mutation and being in mutation selection ... recombination and DUS distribution may be caused by selection for recombination, by selfish molecular drive, or by both. Simple preliminary analysis of the degeneracy of DUSs a...

Ngày tải lên: 14/08/2014, 08:20

... seriously, in 2005 there were seven women and four men were infected by ORFV in Fujian province. So, orf is a national zoonoses in China. In this study, we diagnosed an outbreak of orf in Chinese goats ... anonymous reviewers for their editing and revision the manuscript. Author Details Lanzhou Veterinary Research Institute of Chinese Academy of Agriculture Science, State Key La...

Ngày tải lên: 12/08/2014, 04:20

... data. ES was involved in experimental design, performed the phylogenetic analysis and sequence analysis. DES, KN, AH and SR were involved in experimental design including providing the isolates ... LS reagent (Invitrogen, Inc., Carlsbad, CA) in accordance with the manufacturer's instructions. Sequencing tem- plates for individual influenza genes were produced by amplifying the...

Ngày tải lên: 12/08/2014, 04:20