Báo cáo y học: "Strategy for encoding and comparison of gene expression signatures" pps

... and comparison of gene expression signatures Yajun Yi * , Chun Li † , Clay Miller * and Alfred L George Jr *‡ Addresses: * Department of Medicine, Garland Avenue, Vanderbilt University, Nashville, ... number, sample names, microarray platform, and group assignments. AESP performs translation of probe IDs, significance tests, and the encoding of gene expression s...

Ngày tải lên: 14/08/2014, 07:22

... flow- cytometry and gene- expression data were available for 29 of 38 controls (76%) and 107 of 199 JIA patients (54%). For an additional part of the study, gene- expres- sion data from PBMC samples of ... Adjustment of systematic microarray data biases. Bioinformatics 2004, 20:105-114. 18. Edgar R, Domrachev M, Lash AE: Gene Expression Omnibus: NCBI gene expressi...

Ngày tải lên: 12/08/2014, 14:22

... activity of a signaling pathway may currently be best characterized by the expression levels of its target genes. In support of this hypothesis, Breslin et al. [13] have shown the capacity of expression ... pathways for the E2F3 gene signatureResults for all pathways for the E2F3 gene signatureClick here for fileAdditional data file 2Results for all pathways for th...

Ngày tải lên: 14/08/2014, 07:21

... repress gene expression. p30 II (as well as the homologous p28 II of HTLV-2) specifically binds tax/rex mRNA and block its export, reducing Tax and Rex and ultimately repressing viral gene expression. ... Schavinsky-Khrapunsky Y, Aboud M: Role of Tax protein in human T-cell leukemia virus type 1 leukemogenicity. Ret- rovirology 2004, 1:20. 6. Franchini G, Nicot C, Johnson J...

Ngày tải lên: 13/08/2014, 13:20

... stages) and generating profiles of fluorescence intensity along the worm body axis. This high-throughput analysis generates spatio- temporal profiles of gene expression. In a preliminary analysis, 304.2 ... that new and improved technologies (such as sequencing, microfluidics, high- density tiling arrays and microscopy) are fueling the rapid expansion of a systems-level underst...

Ngày tải lên: 14/08/2014, 07:21

... of Biochemistry, Stanford University, Stanford, CA 94305, USA. ‡ Department of Genetics, Stanford University, Stanford, CA 94305, USA. § Howard Hughes Medical Institute, Stanford University, ... Genome Biology 2005, 6:404 Correction Correction: A DNA microarray survey of gene expression in normal human tissues Radha Shyamsundar* † , Young H Kim*, John P Higgins*, Kelli Montgomery*...

Ngày tải lên: 14/08/2014, 14:22

... bactericidal activity and therefore should cover SCVs of staphylococci 35 . It is likely to penetrate glycocalices very rapidly 36-38 . Once incor- porated in biofilm Vancomycin shows a strain ... S. In vitro study of the efficacy of acrylic bone cement loaded with supplementary amounts of gentamicin: effect on mechanical properties, antibiotic release, and biofilm formatio...

Ngày tải lên: 26/10/2012, 09:53

... neuropathy confirmed by electromyography, or the diagnosis of Sjögren syndrome based on the clinical symptoms of dry eyes and dry mouth (confirmed by a positive Schirmer's test and/ or kerato- conjunctivitis ... kerato- conjunctivitis sicca with involvement of salivary glands docu- mented by positive lip biopsy and/ or salivary scintigraphy). Simple x-rays of the hands and...

Ngày tải lên: 09/08/2014, 10:20

... the complexity of mappings between probesets of different plat- forms, and comparability of normalizations. Fortunately, the number of various platforms for each model organism is rel- atively low and ... the standard devia- tion for each gene in each experiment. We also performed a MEM query with each of the genes and used similarity score cutoff that yielded on average...

Ngày tải lên: 09/08/2014, 20:21

... 1 Department of Medicine, State University of New York at Buffalo, NY, USA, 2 Department of Family Medicine, State University of New York at Buffalo, NY, USA, 3 Department of Internal medicine, ... medicine, University of Iowa, IA, USA, 4 Department of Medicine, Rochester General Hospital, Rochester, NY, USA, 5 Department of Medicine, University of Rochester, NY, USA,...

Ngày tải lên: 11/08/2014, 05:21