Báo cáo y học: " Genome position and gene amplification" potx

... copy number is only one way to alter expression of a gene and expression of other oncogenes is much less tightly linked to DNA copy number or amplification. Other mechanisms for deregulation may ... expression of upstream genes. Tumor subtypes may also be distinguished by their propensity to amplify oncogenes, suggesting that the particular types of genomic instability present in a tumor...

Ngày tải lên: 14/08/2014, 07:21

... regions. SNP and nsSNP denote synonymous and non-synonymous SNPs, respectively. OMIM, Online Mendelian Inheritance in Man. Fang et al. Genome Biology 2011, 12:R63 http://genomebiology.com/2011/12/7/R63 Page ... and JW designed the study; XF, YZ, RZ, XG LY, ML and KY carried out sequencing and data analysis; XF, YZ, RZ, JW and BS wrote the manuscript. All authors read and appro...

Ngày tải lên: 09/08/2014, 23:20

... Pathophysiology of prone positioning in the healthy lung and in ALI/ARDS. Minerva Anestesiol 2001, 67 :238-247. 26. Mackenzie CF: Anatomy, physiology, and pathology of the prone position and postural drainage. ... hemodynamics during lung recruitment maneuvers at hypovolemia, normovolemia and hypervolemia: a study by echocardiography and continuous pulmonary artery flow measuremen...

Ngày tải lên: 14/08/2014, 08:21

... replication [3], and only a small fraction (typically around 10%) of the genes are highly transcribed. These ‘clumps’ or regions of highly expressed genes can be seen as dark bands in Figure 1, and some ... with highly expressed genes found by Jeong et al. [1]. However, the majority of cellular DNA is compacted transiently by chromatin proteins, and there are many regions that are not h...

Ngày tải lên: 14/08/2014, 14:21

... physiological and pathological conditions are yet to be probed by tiling arrays, and the amount and complexity of the information generated by high-density whole human genome tiling arrays may ... tissues Gene expression profiles for human prostate, kidney and liver were obtained with the 44 k intron-exon oligoarrays. Arrays were hybridized with amplified Cy3- and Cy5-labeled cR...

Ngày tải lên: 14/08/2014, 20:22

... 17:890-896. 41. Yang Z: PAML: a program package for phylogenetic analysis by maximum likelihood. Comput Appl Biosci 1997, 13:555. 42. Yang Z, Nielsen R: Estimating synonymous and nonsynony- mous substitution ... insects and worms, and yeast and plants). A gene with a homolog only in mammals is considered a mam- malian gene, and a gene with a homolog only in the primates is cons...

Ngày tải lên: 14/08/2014, 21:20

... pathway (Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway ko00130): a methyltransferase belonging to the ubiE/COQ5 family (EC:2.1.1 ; Tg1226), 3- octaprenyl-4-hydroxybenzoate carboxy-lyase ... Hayatsu H, Pavlov YI: HAM1, the gene controlling 6-N- hydroxylaminopurine sensitivity and mutagenesis in the yeast Saccharomyces cerevisiae. Yeast 1996, 12:17-29. 77. Sheikh S, O'Handle...

Ngày tải lên: 14/08/2014, 21:20

... [http://tinman. nikunnakki.info] 5. MMyy ffaavvoorriittee ggeennee nnaammeess [http://jpetrie. myweb.uga.edu/genes.html] 6. FFuunnnnyy ggeennee [http://www.gersteinlab.org/ proj/funnygene] http://genomebiology.com/2008/9/1/401 Genome BBiioollooggyy 2008, ... * Program in Computational Biology and Bioinformatics, † Department of Molecular Biophysics and Biochemistry, and ‡ Departmen...

Ngày tải lên: 14/08/2014, 08:20

... importance and phylogenetic position, B. rapa provides a crucial reference to understand polyploidy-related crop genome evolution. The high degree of sequence identity and remarkably conserved genome ... to understand angiosperm biology and evolution. As of 2009, the genome sequences of only five eco- Synteny between the B. rapa and A. thaliana genomesFigure 2 (see previous pag...

Ngày tải lên: 09/08/2014, 20:20

... displays significant regulation by carbon and/ or nitrogen. This analysis revealed several primary funcats (01 = metabolism, 02 = energy and 05 = protein syn- thesis) that are significantly under-represented ... global understanding of the genes and processes that are regulated by carbon and nitrogen signaling in plants and the mechanism by which this occurs is still lacking. Previou...

Ngày tải lên: 14/08/2014, 14:21