Báo cáo y học: "Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes" pdf
Báo cáo y học: "Detailed analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromes" pdf
... analysis of 15q11-q14 sequence corrects errors and gaps in the public access sequence to fully reveal large segmental duplications at breakpoints for Prader-Willi, Angelman, and inv dup(15) syndromesAndrew ... is located near the end of contigNT_010280 (Figure 3), from where the duplications presum-ably originate. Examination of the sequence at the beginning of NT_078096 revealed part of an inverted ... facilitated the analysis of alignments from the BLAST 2 SEQUENCES procedure bydownloading the data into Microsoft Excel to generate a list of co-ordinates of all strong alignments for each pair of sequences....
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Báo cáo y học: " Structural analysis of bacteriophage T4 DNA replication: a review in the Virology Journal series on bacteriophage T4 and its relatives" pptx
... loadingprotein also delays progression of the leading strandpolymerase, allowing for the assembly and coordination of lagging strand synthesis. Once gp41 helicase isassembled onto the replication ... summary of our collaborative efforts with the late Dr. Nossal, and also the work of many others, that, in total, has created a pictorial view of prokaryotic DNAreplication. A list of proteins of the ... assists in the unwinding of DNA and the gp43 DNA polymeraseextends the invading strand primer into the next genome,likely co-opting the E. coli gyrase (topo II) to reducedpositive supercoiling...
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Báo cáo y học: "Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case– control study" docx
... and drafted the manuscript. TH, RG, HK, GRB, and AS partici-pated in the coordination of the study and in drafting the man-uscript. TD participated in the design and coordination of the study, and ... 50:1117-1121.11. Barton A, Bowes J, Eyre S, Symmons D, Worthington J, Silman A:Investigation of polymorphisms in the PADI4 gene in deter-mining severity of inflammatory polyarthritis. Ann Rheum ... deimination of protein-boundarginine to citrulline [1]. Five different types of peptidylargininedeiminases encoded by the genes PADI1–PADI4 and PADI6are currently known [1]. The presence of...
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Báo cáo y học: " Transcriptome analysis of murine thymocytes reveals age-associated changes in thymic gene expression"
... both in total number and in maturity, within the thymus. The increase in B cell numbers in the thymus with age seems too small to account for the greatly increased quantities of immunoglobulin ... samples and blue lines the old samples. Flow cy-tometry demonstrates that there is a clear shift in the mean fluorescence intensity of IgM in the old thymocytes when compared to the young thymocytes. ... real-time RT-PCR to determine the relative amounts of IgM being produced by young and old thymocytes. As shown in Figure 9, the majority of the IgM production in the thymus originates from the non-T...
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Báo cáo y học: "An analysis of correlations among four outcome scales employed in clinical trials of patients with major depressive disorder" pdf
... frombaseline for MADRS and HAM-D17, change in score frombaseline for CGI-S, and end point scores for CGI-I. Thesescores were calculated using observed data for the totalpatient populations at ... duration of treatment; these analyses evaluated treat-ment effects with a variety of antidepressants, includingtricyclic antidepressants, selective serotonin reuptakeinhibitors, and serotonin-norepinephrine ... assesses the degree of symptom improvement rather than absoluteseverity of symptoms or specific pathology [3]. The HAM-D and the MADRS scales measure depressive symptoms,whereas the CGI-S and CGI-I...
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Báo cáo y học: " Transcriptome analysis of functional differentiation between haploid and diploid cells of Emiliania huxleyi, a globally significant photosynthetic calcifying cell" potx
... allowed to recover in K/2 medium for >4 weeks before washing again and incubating in 50 μg ml-1 ampicillin, 50 μg ml-1 streptomycin dissolved in K/2 medium, incubating for 4 days, and then ... previously been used for analysis of EST libraries [96], and using a ML estimatordeveloped for EST analysis [23]. The ML analysis was per-formed by artificially dividing the ESTs into two sets ... fraction of our EST datasets thus likely provides for- merly inaccessible information on E. huxleyi transcriptomes.One of the primary objectives of this study was to estimate the extent to which the...
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Báo cáo y học: " Cost analysis of an integrated disease surveillance and response system: case of Burkina Faso, Eritrea, and Ma" pot
... approximately half of buildings in each coun-try. The second category of missing data involved cost data for the laboratory testing and treatments from BurkinaFaso. To fill in for the structure and ... lab-oratory and treatment data. Instead, we extrapolated the costs from average annual cost of laboratory supplies and treatment for Eritrea and Mali. Without the laboratory and treatment costs, the ... activities.§ Investigation, verification and laboratory confirmation of suspected cases.† Other support activities include training, supervision, communication and coordination.¶Laboratory and treatment...
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Báo cáo y học: "Comparative analysis of Saccharomyces cerevisiae WW domains and their interacting proteins" pps
... biotinylated antibodies for the detection of the biotinylated probes and gluthathione S-transferase for the analysis of binding specificity. In Y2 H experiments with sev-eral of these WW domains ... encompassing for yeast the great majority of proteins, including proteins of low cellu-lar abundance; they are rapid to screen and analyze; and theylikely contain proteins that exhibit native ... proteins may be present on the array; and the mod-ification of array probes (for example, biotinylation) mayinfluence their binding properties.Classification of WW domains in yeast The WW domain...
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Báo cáo Y học: Kinetic studies of human tyrosyl-DNA phosphodiesterase, an enzyme in the topoisomerase I DNA repair pathway pot
... repair pathway, and inhibitors of TDP may have therapeutic utility in treatingcancers that are refractory to camptothecin treatment. In order to understand the structure–activity relationship of TDP ... due to the hydrolysis of substrateby water, by heating the enzyme at 70 °C for 15 min prior to the assay. The enzyme reactions carried out with heatedFig. 1. Sequence alignment of human and yeast ... DNA,unwinding and religating the DNA ends in the cleavedstrand [1]. During the process, DNA becomes covalentlylinked to Topo I via the 3¢ phosphate and forms a catalyticintermediate, i.e....
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Báo cáo y học: " Protective effect of vasoactive intestinal peptide on bone destruction in the collagen-induced arthritis model of rheumatoid arthritis" pptx
... shown to promote osteoclast differentiation and activation. To study the local expression of these factors we performedquantitative RT-PCR of the enzymes involved in the synthesis of these mediators ... (cyclooxygenase-2 (COX-2) and inducibleFigure 1Cytokine circulating levels in mice at the end of treatment in the collagen-induced arthritis (CIA) modelCytokine circulating levels in mice at ... potent mediatorsinduced by inflammatory cytokines that stimulate their osteo-clastogic activities. They are also inhibited in the joints of VIPtreated mice, as can be deduced from the lower...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Định tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘITÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ