... together, these observations suggest the development of cartilage degeneration and bone resorp-tion in group I, possibly in the progression stage. On the other hand, CTSG, the gene for cathepsin ... suggestions concerning orthopedics. NT, KY,SN, and SY carried out the clinical studies of each case and performed targeted biopsy of synovial tissues with the informed consent of the patients. MN conceived ... structure of the intimal lining cells and the presence of non-foreign-body-type giant cells, formation of lymphoid follicles, and massive accumulation of plasma cells and macrophages [1]. Mesenchymoid...