Báo cáo y học: "Comparison of Francisella tularensis genomes

Báo cáo y học: "Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains" potx

... duplicated pathogenicity island, of which there is only one copy in U112 [26]. The duplication of the Francisella pathogenicity island may provide a higher level of expression of the virulence genes ... nonpathogenic to humans provides a coarse chronology of the evolutionary events that took place during the emergence of the former A reduced set of genes wa...

Ngày tải lên : 14/08/2014, 07:21

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Báo cáo y học: "κ Increased AP-1 and NF-κB activation and recruitment with the β combination of the proinflammatory cytokines IL-1β, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocyte" ppt

... inflammatory disease characterized by the infiltration of the synovial membrane with monocytes/T cells, by the proliferation of synovial lining cells and by the production of proinflammatory cytokines, which ... Conversely, in RA synoviocytes, we found a higher effect of the combination of IL-17 with IL-1β than with TNF-α. The strongest effect was observed for the...

Ngày tải lên : 09/08/2014, 01:23

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Tài liệu Báo cáo Y học: Granule-bound starch synthase I A major enzyme involved in the biogenesis of B-crystallites in starch granules ppt

... followed the kinetics of amylose synthesis over a 5-day period of nitrogen starvation and measured the amounts of starch, amylose, the k max of the starch fractions, the degree of crystallinity and the ... course of storage starch synthesis show that amylopectin and amylose synthesis are partly disconnected and that amylose synthesis persists when the rate of polys...

Ngày tải lên : 22/02/2014, 07:20

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Báo cáo Y học: Cytochrome c from a thermophilic bacterium has provided insights into the mechanisms of protein maturation, folding, and stability potx

... T., Yamazaki, K., Kyogoku, Y. & Kobayashi, Y. (1998) Solution structure of thermostable cytochrome c-552 from Hydrogenobacter thermophilus determined by 1 H-NMR spectroscopy. Biochemistry ... a heme covalently attached to the polypeptide chain via two thioether bonds, formed from the vinyl groups of the heme and the two cysteine residues in the consensus Cys-X-X- Cys-His...

Ngày tải lên : 24/03/2014, 03:21

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Báo cáo y học: "Most nuclear systemic autoantigens are extremely disordered proteins: implications for the etiology of systemic autoimmunity" pps

... of spreading. In a key study [42] they showed that immunization of rabbits with the peptide PPPGMRPP, a repeated sequence within the carboxyl terminus of Sm B/B', led to a spreading of the ... supports both of these predictions. At the same time the model explains why, para- doxically, some type of T cell-B cell contact is required in the development of autoim...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "THR0921, a novel peroxisome proliferator-activated receptor gamma agonist, reduces the severity of collagen-induced arthritis" pps

... delayed the onset of arthritis as well as significantly reducing the clinical disease activity score during the course of the experiment compared with CIA mice (Figure 1). From day 28 on, the ... inflammatory cytokines are thought to play a critical role in the pathogenesis of RA, we monitored the production of the proinfammatory cytokines TNF-α, IL-1β, and INF-γ as...

Ngày tải lên : 09/08/2014, 07:20

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Báo cáo y học: "Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer''''s patches in an orally tolerized, collagen-induced arthritis mouse model" ppt

... approved by the Animal Research Ethics Committee at the Catholic University of Korea. Preparation of type II collagen Bovine CII was kindly provided by Professor Andrew Kang of the University of Tennessee. ... erythema limited to the foot or ankle, 2 = slight edema and erythema from the ankle to the tarsal bone, 3 = moderate edema and erythema from the ankle to the tar...

Ngày tải lên : 09/08/2014, 10:22

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Báo cáo y học: " High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease." docx

... perspective on the dynamics of these molecules inside the cell and the diversity of activities that these molecules display once they are outside. Competing interests The authors declare that they have ... cells and amplify their activity because of their physical association (Figure 1). In its stimulation of the immune system, HMGB1 may differ from conventional cytokines in...

Ngày tải lên : 09/08/2014, 10:23

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Báo cáo y học: "Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis" ppsx

... indicated by a spot, with the intensity of the spot representing the proportion of significantly differentially expressed transcripts for each one of the transcriptional modules. The color of the spot ... (HMFN0839)* 1-Acylglycerol-3-phosphate O-acyltransferase 9 [GenBank:NM_032717.3 ] 34 MTHFD2 Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetr...

Ngày tải lên : 09/08/2014, 20:20

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Báo cáo y học: " Protein kinase A-dependent Neuronal Nitric Oxide Synthase Activation Mediates the Enhancement of Baroreflex Response by Adrenomedullin in the Nucleus Tractus Solitarii of Rats" pps

... microinjection of the test agent into NTS. The BRR response was represented by the ratio of the peak magnitude of reflex bradycardia to the peak magnitude of phenylephrine-induced pressor response. The averaged ... neuron. The enzyme activity of nNOS has been demonstrated to be intimately associated with the state of phosphorylation at the amino acid residu...

Ngày tải lên : 10/08/2014, 05:21

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