Báo cáo y học: "An annotation infrastructure for the analysis and interpretation of Affymetrix exon array data" pot

... System's XRAY, JMP ® Microar- ray, Partek ® Genomics Suite, and Stratagene's ArrayAssist ® . Many of them are extensions of previously known software products for standard arrays, and their ... integration with the analytical libraries of R and all are proprietary and licensed, while the X:MAP database and exonmap are free and open source (available at [18,...

Ngày tải lên: 14/08/2014, 07:21

... biosynthetic pathway, the catalyzing enzymes and their transcriptional control. The state of internal leucine depends on the leucine transport into the cell and on the yield of the leucine biosynthetic ... activa- tor of enzymes that catalyze several amino acid biosynthesis pathways, including the leucine biosynthetic pathway. The control of several catalyzing enzy...

Ngày tải lên: 14/08/2014, 08:20

... without mutation in the corresponding sequence data then serve as a proxy indicator of non-adherence. Implications of the hypothesis: It is envisaged that the validation of the hypothesised approach ... recent analysis showed that life expectancy at age 20 years had increased by over 13 years since the introduction of combination antiretro- viral therapy and currently li...

Ngày tải lên: 10/08/2014, 05:21

... Greece. 2 Department of Anesthesiology, University of Thessaly, Larissa, Greece. Authors’ contributions G T is the main author of the manuscript and member of the surgical team. DK coauthored the paper. ... aortic surgery. Conflicts of interest The authors declare that there are no conflicts of interest. Author details 1 Department of Cardiovascular and Thoracic Su...

Ngày tải lên: 10/08/2014, 09:22

... MMP-1 and MMP-3 in cartilage and SFB by TNF- α and/ or IL-1β [42,43]. Therefore, they support the validity of the new model for the analysis of the mechanisms of cartilage destruction by SFB. ... demonstrates the formation of a SFB multi- layer on the cartilage surface. (c) Immunostaining for prolyl-4-hydroxylase verifies the viability of SFB and chondrocy...

Ngày tải lên: 09/08/2014, 01:22

... inflammatory and resident mono- cytes is a potential biomarker for monitoring disease activity and success of therapy in systemic lupus erythematosus. Arthritis Rheum 2008, 58:1136-1145. 28. Yao Y, Richman ... Autoimmunity 2003, 36:481-490. 21. Han GM, Chen SL, Shen N, Ye S, Bao CD, Gu YY: Analysis of gene expression profiles in human systemic lupus erythe- matosus using oligonuc...

Ngày tải lên: 09/08/2014, 14:22

... were then washed with 50 ml of warm DC-CM and 60 ml of DC-CM containing 800 U/ml GM-CSF and 1,000 U/ml IL-4 was added. The cells were incubated for 4–5 days and matured for 20–24 h and analyzed for mature ... incubation and stained for CD11c, CD13, CD14, CD83 and CD86 and analyzed by flow cytometry. In each case all the isolated floating cells were analyzed wit...

Ngày tải lên: 11/08/2014, 10:23

... similar to peptidylprolyl isomerase A isoform 1; inversin isoform a; inversin isoform b; 9890 bp at 5' end: hypothetical protein LOC158405; 17561 bp at 3' end: hypothetical protein ... contributions BW and WM conceived of the study, conducted the in silco analyses and contributed to drafting the final manuscript. BW, WM and KH participated in data analysis and writ...

Ngày tải lên: 13/08/2014, 16:20

... the development of alcoholism, despite the fact that the theory of a distinct type of personality that leads to alcohol dependency has been rejected. Idiosyn- crasy and personality traits have ... anxiety. Generalisation may lead to a variety of new stimuli that reinforce the habit of alcohol consumption [32]. These theories not only offer information about diagno- sis, bu...

Ngày tải lên: 08/08/2014, 23:21

... an anti-inflammatory type [26]. This relative deviation of the cytokine response, caused either by decreased Th1-type cytokines and/ or by enhanced Th2-type cytokines leading to the regression of an autoimmune ... need to systematically study and define the mechanisms underlying the activity of CAM products that have been used for the treatment of rheumatic diseases in...

Ngày tải lên: 09/08/2014, 10:20