Báo cáo y học: "Gene expression analysis of nuclear factor I-A deficient mice indicates delayed brain maturation" pot

... the original work is properly cited. Delayed brain maturation in NFI-A -deficient mice& lt;p>Gene expression analysis of brains from mice deficient in nuclear factor I-A (<it>Nfia</it><sup>-/- ... Access 2007Wonget al.Volume 8, Issue 5, Article R72 Research Gene expression analysis of nuclear factor I-A deficient mice indicates del...

Ngày tải lên: 14/08/2014, 07:21

... erythrocyte proteome: analysis by ion trap mass spectrometry. Mollecular und Cellular Proteomics 2004;3:501-509. 9. Tyan YC, Jong SB, Liao JD et al. Proteomic profiling of eryth- rocyte proteins by ... deter- mination of erythropoiesis, apoptosis and may have implications on the pathophysiology and diagnosis of various diseases involving red blood cells. Key words: red blood cell...

Ngày tải lên: 03/11/2012, 10:58

... directly regulated by LEAFY COTYLEDON2 provide insight into the control of embryo maturation and somatic embryogenesis. Proceedings of the National Academy of Sciences of the United States of America ... Dihydroflavonol reductase (DFR) activity is the committing step for leucoanthocyanidin synthesis and proanthocyanidin, anthocyanidin and anthocyanin synthesis follows this step [50]...

Ngày tải lên: 11/08/2014, 11:22

... severity, wild- type D2 mice have significantly lower expression of the Smad4 transcription factor, also involved in the control of hepcidin expression, than wild-type B6 mice. Confirmation of differential ... NS Hadh2 Hydroxyacyl-CoA dehydrogenase type II NS -4.05 -4.61 Acox1 Acyl-CoA oxydase 1, palmitoyl (peroxisomal) -2.10 -1.63 -4.27 Cyp4a10 Cytochrome P450 4A10 -6.76 -2.46...

Ngày tải lên: 14/08/2014, 08:20

... properly cited. Factors affecting gene expression in the brain& lt;p>The transcriptional profiles of five regions of the central nervous system (CNS) of mice varying in age, gender and dietary intake ... aging. Prior gene expression studies of brain aging included only young and old animals of one gender, typically used microar- rays with relatively few genes and often a...

Ngày tải lên: 14/08/2014, 08:20

... Heslington, York YO10 5NY, UK. † YCR Cancer Research Unit, Department of Biology, University of York, York YO10 5YW, UK. ‡ Hull York Medical School, University of York, Heslington, York YO10 5DD, ... R83.6 Validation of selected genes by flow cytometry and immunocytochemistryFigure 4 Validation of selected genes by flow cytometry and immunocytochemistry. (a) Flow cytometry anal...

Ngày tải lên: 14/08/2014, 08:21

... inflammatory pathways by IL-1β through revoking activation of caspase-3, produc- tion of COX-2, phosphorylation of Iκ-Bα and inhibition of nuclear translocation of NF-κB. Interestingly, although ... MTT: 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; NF: nuclear fac- tor; NF-κB: nuclear factor- κB; OA: osteoarthritis; PAB746: polyclonal anti-colla- gen type II...

Ngày tải lên: 12/08/2014, 14:22

... variation in PCR assays is slightly greater than that required for a clinical laboratory analysis [26], the precision is sufficient to allow detection of twofold differences. Analysis of individual ... Similarly, synovial fluid can be obtained rel- atively easily by joint aspiration but its utility is markedly diminished by the fact that the volumes are highly variable and effusions a...

Ngày tải lên: 09/08/2014, 01:23

... Interestingly, antisense oligonucleotides of c-myc can induce apoptosis and downregulation of Fas expression in synoviocytes [37]. The present study demonstrates the potency of IL-17, IL-1β, and TNF-α alone ... or definite RA (range of ages 27–71 years, with a mean age (± SEM) of 51.9 ± 16.4 years) undergoing surgical syn- ovectomy, by dissociating the minced tissue enzymati- call...

Ngày tải lên: 09/08/2014, 01:22

... kinetics of expression using Spotfire ® profile search and K-mean cluster analysis. Microarray-based data for a subset of genes were validated using real-time PCR TaqMan ® analysis. Analysis of the microarray ... Affymetrix ® MicroArraySuite software (MAS 5.0). Statistical analysis of microarray data The Affymetrix GeneChip ® data were processed, normal- ized and statistica...

Ngày tải lên: 09/08/2014, 06:22