Báo cáo y học: "Decline of nucleotide excision repair capacity in aging Caenorhabditis elegan" potx

... Effects of p-Synephrine alone and in Combination with Selected Bioflavo- noids on Resting Metabolism, Blood Pressure, Heart Rate and Self-Reported Mood Changes Sidney J. Stohs 1 , Harry G Preuss 2  , ... weight control agent. Key words: p-Synephrine, naringin, hesperidin, resting metabolic rate, heart rate, blood pressure Introduction The bi...

Ngày tải lên: 25/10/2012, 11:04

... Characterization of erythrovirus B19 genomes isolated in liver tissues from patients with fulminant hepatitis and biliary atresia who underwent liver transplantation Kenji Abe 1 , Tetsuya Kiuchi ... words: Erythrovirus B19; erythrovirus B19 genome; fulminant hepatitis; biliary atresia; liver transplantation 1. Introduction Erythrovirus...

Ngày tải lên: 26/10/2012, 10:03

... Discussion and Conclusions To address the question whether the +T294C polymorphism in PPAR is associated with the risk for coronary heart disease and/ or plasma lipid levels in women, we investigated ... state the activities of numerous interacting genes are altered which may influence the effect of PPAR on metabolism. In our data and in the stu...

Ngày tải lên: 31/10/2012, 17:03

... determined by its p osition in t he Ó FEBS 2002 Predicting protein–protein interaction sites (Eur. J. Biochem. 269) 1357 Prediction of protein–protein interaction sites in heterocomplexes with neural ... recently, methods were devised for predicting residues involved in protein interaction s ites in the absence of any structural reports. By analysing hydroph...

Ngày tải lên: 21/02/2014, 15:20

... Induction of (2Â)5Â)oligoadenylate synthetase in the marine sponges Suberites domuncula and Geodia cydonium by the bacterial endotoxin lipopolysaccharide Vladislav A. ... to 24 h . The i dentity of the p 3 A 2 product synthesized by the (2–5)A synthetase both in tissue and in primmorphs of S. domuncula was verified by TLC and HPLC ana...

Ngày tải lên: 21/02/2014, 15:20

... project. A wing disc cDNA library derived from fifth instar B. mori C108 larvae was kindly provided by Dr Kawasaki (University of Utsunomiya, Japan). A total of 1000 clones were s elected at random and ... 26 9) Ó FEBS 2002 Characterization of a novel silkworm ( Bombyx mori ) phenol UDP-glucosyltransferase Teresa Luque 1 , Kazuhiro Okano 2 and David R. O’Reill...

Ngày tải lên: 22/02/2014, 04:20

... decrease in the activity for the 11b-hydroxylase, CYP11B1 . Intriguingly, however, the 11b-hydroxylase activity of the aldosterone synthase CYP11B2 was basically unaffected whereas the 18-hydroxy- lation ... frame. Thus, the guinea pig presumably branched off at a very early time point within the mammalian radiation irrespective of the branching order. In...

Ngày tải lên: 22/02/2014, 07:20

... methods). Bar indic ates 200 nm. Ó FEBS 2002 Tau aggregates in cultured cells (Eur. J. Biochem. 269) 1487 Formation of aberrant phosphotau fibrillar polymers in neural cultured cells Mar Pe ´ rez 1 ,Fe ´ lix ... protein [3,4] that in pathological situations, and in a hyperphosphorylated form [5–8] assembles into fibrillar polymers. The mechanism for that a...

Ngày tải lên: 08/03/2014, 16:20

... damaged or inappropriate bases in DNA is base excision DNA repair (BER) [8–10]. The initial step of BER involves enzymatic activities that process the N-glycosylic bonds linking the target bases and ... structurally distinct abasic sites, known as oxidized abasic sites. Oxidized abasic sites include lesions at DNA strand breaks, such as 3Â-phosphoglycolate esters...

Ngày tải lên: 16/03/2014, 13:20

... for Zn-induced apoptosis in human Burkitt lymphoma B cells. An increase in labile Zn in the cytoplasm may suppress apoptosis by inhibition of the action of caspase, cytoplasmic apoptosis inducer, ... [53,54]. Caspases, a family of cysteine proteases, play a pivotal role in the execution of apoptosis [26]. We therefore examined the involvement of caspases in the...

Ngày tải lên: 23/03/2014, 21:20

... comparative terms, the Kenyan estimate of 10% of the Ministry of Health budget is lower than that of the Netherlands and Table 1: Annual cost of operating and organizing psychiatric services in Kenya (1 US$ ... those borne by the health care system and the family in directly addressing the problem of MBD; and (b) the indirect costs, i.e. loss of productivity caused b...

Ngày tải lên: 08/08/2014, 20:23

... block intracellular enzymes that control signaling pathways. Inhibitors of tyrosine kinases expressed in lymphocytes, such as spleen tyrosine kinase and Janus kinase, are being tested in autoimmune ... few key cytokine targets are discussed. Review Garden of therapeutic delights: new targets in rheumatic diseases Jean M Waldburger and Gary S Firestein Division of Rheum...

Ngày tải lên: 09/08/2014, 01:22

... rearrangements in the patient s parotid gland only, as well as of Vλ1C–Jλ3 rearrangements in both the peripheral blood and parotid gland of this patient with SS. One feature of the present patient ... from the peripheral blood of the same patient. This patient manifested increased titers of autoantibodies (anti-Ro and anti-La), hypergamma- glo...

Ngày tải lên: 09/08/2014, 03:24

... osteochondrodysplasia, osteoporosis Meeting report Genetics of osteoarticular disorders, Florence, Italy, 22–23 February 2002 Alberto Falchetti Department of Internal Medicine, University of Florence, Florence, ... therapy. Genetics of osteoporosis Presentations on the genetics of OA were given by L Masi, L Gennari and A Falchetti (Department of Internal Medicine, Un...

Ngày tải lên: 09/08/2014, 06:22

... 8, Issue 5, Article R70 Research Decline of nucleotide excision repair capacity in aging Caenorhabditis elegans Joel N Meyer * , Windy A Boyd † , Gregory A Azzam * , Astrid C Haugen * , Jonathan ... young and aging adults, respectively. Finally, repair was reduced by 30% to 50% in each of the ten nuclear regions in aging adults. However, this decrease in repair...

Ngày tải lên: 14/08/2014, 07:21