Báo cáo y học: "Towards the uniform distribution of null P values on Affymetrix microarrays" doc

... (black lines) presents the P values reported by the R implementation of the cyber t test. We see that, despite the correction for lack of independence by increasing the number of degrees of freedom, the P ... vigorously disputed by the authors of the Choe dataset, who argue that the non -uniform distribution of P values may be a common feature of m...

Ngày tải lên: 14/08/2014, 07:21

... the resolution of species distribution considerably on the national surveys conducted in the 1960s, 1970s and 1980s. While most of the survey data were based largely on personal experiences and ... and Panax ginseng [27-29]. The present study aims to characterize the eco-environ- mental conditions in the A. annua L. production areas in Youyang County and predict the...

Ngày tải lên: 13/08/2014, 15:21

... radiographic damage. Since the perspective of the patients in the experience of health is increasingly important, insight into the type of psychological variables, the pathways by which they in ... the personal factors. Depression, as in the study by Brionez and coworkers [1], is part of the body functions (emotional function) – and as such can be the direct co...

Ngày tải lên: 12/08/2014, 11:22

... unique per- spective on the application of exciting experimental break- throughs at the interface of genomics, cell biology and optical physics. Acknowledgements I thank Thoru Pederson, Christoph ... (z-dimension) by the use of two opposing objective lenses to propagate light from multiple directions toward the focal point, followed by a deconvolution step to give a z-resolut...

Ngày tải lên: 14/08/2014, 16:20

... amounts of time and effort for expanding the system's lexicon. Furthermore, if the compiled infor- mation depends in any way on the domain of the application, the acquisition of lexical ... the number of clusters they considered most appropriate; con- sequently, the models with high recall/low precision are the ones with a small number of clusters, while...

Ngày tải lên: 08/03/2014, 07:20

... Triples can be easily acquired from automatically parsed corpora. While the relation word is usually part of the utterance that represents the source of the relation, determining the appropriate ... eval- uation experiments. The portion analyzed here com- prises 33.2M sentences, 75.9% of the corpus. The extraction of events in these corpora uses simple patterns that co...

Ngày tải lên: 16/03/2014, 20:20

... are considerably close to the range of values for 3 10 helix. Additionally, Leu14 possess a u torsion angle almost typical for the 3 10 helix. In this region of the polypeptide chain, the secondary structure ... quality of the peptide structure and provide the elements of the secondary structure, as well as other statistical parameters. RESULTS NMR spectra–proton assig...

Ngày tải lên: 17/03/2014, 10:20

... the amino terminus by insertion of PCR products into the BglII and PspAI sites of plasmid phsp70HAHisVI+ containing the 5¢ terminal amino acid sequence RYPYDVPDYARA. The sequence YPYDVPDYA constitutes ... with 2 lg of the reporter plasmid pCAPCAT, and either 0.5 lg of each of the clones of the overlapping AcMNPV k library or 1.0 lg of each plasmid of the overla...

Ngày tải lên: 23/03/2014, 21:20

... ATP and/or ADP /P i binding to the tetraprotomeric form of Na/K- ATPase accompanying catalytic phosphorylation-dephosphory- lation cycle. J. Biol. C hem. 274, 3 1792±31796. 43. Winter, R. & ... directly affected by pressure effects. The phas e transition of a lipid bilayer f rom the liquid crystalline phase to a gel phase is accompanied by an increase in the thickness of t...

Ngày tải lên: 24/03/2014, 00:21

... delivery. Another strategy is the conjugation of mitochondrial signal peptides to oligonucleotides, similar to nuclear signal peptides. By imitating mitochondrial entry of polypeptides that are synthesized ... transported easily in the cytoplasm. Fourth, they should enter the nucleus easily. For transfection in vivo,this is one of the most important hurdles. Finally, cytotoxity...

Ngày tải lên: 31/03/2014, 08:20