Báo cáo y học: "Mouse maps of gene expression in the brain" pot

... normally express the gene of interest. The advantage of using the BAC as a cloning vector is that it can carry as much as 200 kb of genomic DNA - typically enough to include most, if not all, of the ... European effort led by Gregor Eichele at the Max-Planck-Institute of Biophysical Chemistry in Göttingen, Germany. In approach, this is a hybrid of the Allen Brain...

Ngày tải lên: 14/08/2014, 07:21

... clus- tering of these genes was then performed to identify gene expression patterns among the study samples. As in the JDM study, a striking increase in the expression of a group of genes previously ... to be induced by IFN was observed in about half of the SLE subjects. The authors identified 23 of the 161 differentially expressed genes as targets of IFN b...

Ngày tải lên: 09/08/2014, 01:23

... other indications of immune activation emerged in the set of over-expressed genes, including pro- inflammatory cytokines, chemokines, granzymes, protein- ases, and receptors for inflammatory ... by the observed set of differen- tially expressed genes. Following hypothesis-driven analyses of NF-κB/Rel and GR activity, additional exploratory analyses analyzed the preva- lence o...

Ngày tải lên: 14/08/2014, 08:20

... may alter gene expression patterns in postmortem human brains. Study of expression levels of 14 genes in human brain autopsy and biopsy samples found significant change in one of the genes, indicating ... down-regulation in the autopsy samples. Interestingly, we also see up-regulation of genes involved in the ubiquitin cycle, protein ubiquitination, and ubiquitin...

Ngày tải lên: 14/08/2014, 16:20

... a PiT1-binding immunoadhesin generated by f using the aminoterminal residues of the GALV (SEATO strain) Env, comprising the signal peptide, the RBD and the proline-rich region, to the rFc tag, herein, ... staining in the cortex of control mice; stained neurons are mostly detected in layer II/III. These neurons are medium-sized with homogeneous cytoplasmic staining. B: Pi...

Ngày tải lên: 10/08/2014, 05:21

... closely related family members is an artifact of hybridization. Profile of microRNA expression in the developing mouse brainFigure 3 Profile of microRNA expression in the developing mouse brain. ... technology for profiling the expression of microRNAs and other small RNAs and apply this technology to the developing mamma- lian brain. Recently, Krichevsky et al. descr...

Ngày tải lên: 14/08/2014, 14:21

... the gene- expression pathway. Stefan Hüttelmaier, from the laboratory of Robert Singer (Albert Einstein College of Medicine, New York, USA), described how the trans-acting factor zipcode-binding protein ... control involving cis-acting RNA elements is the regulation of translation of maternally inherited mRNA by cytoplasmic polyadenylation in Xenopus oocytes. Polyadenylat...

Ngày tải lên: 14/08/2014, 14:21

... we show that the mode of duplication, the function of the genes involved, and the time since duplication play important roles in the divergence of gene expression and, therefore, in the functional ... duplicated genes and N is the number of samples. In evaluating and comparing the dis- tributions of the correlation coefficients of the expression of...

Ngày tải lên: 14/08/2014, 16:21

... translation parameter. In this system, we use the Gabor function as the mother wavelet. The equation is given by: where ω p is the center of frequency and λ is the frequency bandwidth. In the present study, ... differences in signal intensity suggest that a superficial collagen network may be maintained in cartilage of the lateral condyle but may deteriorate in...

Ngày tải lên: 09/08/2014, 10:23

... aware of the initial injury and at times, deeply penetrating splin- ters cannot be visualized. In these cases, unfortunately, the only indication of retained foreign material might be swelling, ... injuries typically have an injury track that leads to the splinter, facilitating detection and removal. Older injuries, however, may present in the context of infection, inflammat...

Ngày tải lên: 11/08/2014, 12:20