Báo cáo y học: " Maturation of the mammalian secretome" doc

... Although these approaches have generated an enormous amount of detailed knowledge on the composition of the secretory pathway, the availability of the complete sequences of several eukaryotic genomes ... supported by a fellowship of the program of Becas de Especializacion en Organismos Internacionales of the Spanish Ministry of Education and Science (MEC). The R....

Ngày tải lên: 14/08/2014, 07:21

Ngày tải lên: 12/08/2014, 18:21

... France The thyrotropin receptor (TSHR) is a member of the G protein-coupled receptor superfamily. It has by now been clearly established that the maturation of the glycopro- teins synthesized in the ... being synthesized, the TSHR, like the other transmembrane N-glycoproteins, is N-glycosylated in the endoplasmic reticulum. After the maturation of the oligosaccha...

Ngày tải lên: 31/03/2014, 08:20

... the platypus. Conclusions: Our analyses show that the platypus has significantly fewer repeats of certain classes in the regions of the genome that have become imprinted in therian mammals. The ... Marilyn B Renfree * Addresses: * Department of Zoology, The University of Melbourne, Melbourne, Victoria 3010, Australia. † Department of Molecular and Cellular Biology, T...

Ngày tải lên: 14/08/2014, 21:20

... step forwards to assess the utility of these questionnaires in another practice setting. Therefore the aim of this observational study was to assess the utility of the MYMOP2 and W-BQ12 health outcomes ... utilised for the study. Patients were invited to participate in the study if they were: over the age of 18 years; had no treatment from any health professional for the...

Ngày tải lên: 25/10/2012, 10:06

... and others were scarcely affected. They further noted that the quantitative data did not adequately capture the bravery of the AMPATH patients or the AMPATH staff. The interviewees emphasized the ... with great bravery to return to the clinic and to obtain their medication refills. ▪ Patients really surprised us. They walked distances, they ran away, they tried again, they cam...

Ngày tải lên: 25/10/2012, 10:31

... idea of the high prevalence of edema in the more advanced grades of cellulite. The lack of specific clinical and laboratory studies hinders research on cyclic edema and the dissemination of ... 5. de Godoy JM, de Godoy Mde F. Physiopathological hypothesis of cellulite. Open Cardiovasc Med J. 2009;31(3):96-7. 6. Godoy JMP, Almeida EMMZNM, Silva SH, Godoy MFG. Pilot st...

Ngày tải lên: 25/10/2012, 10:51

... components by use of the inverse Diels Alder technology. The high chemical stability and the ease of synthesis qualify these polyamide building blocks as favourites for intracellular delivery and ... reactivity of the pentenoyl group compared with the dienophile groups in the amide based monomer functionalized with the “Reppe Anhydride” allows the synthesis of p...

Ngày tải lên: 25/10/2012, 11:00

... such as the application of local anesthetics, treat only the somatic component of pain, whereas attention-diverting measures (pressing ball) address only the psychological component of pain. ... Spinal anesthesia; Valsalva maneu- ver. Introduction Spinal anesthesia is a simple and reliable method of anesthetizing lower part of body. However many people refuse it because...

Ngày tải lên: 25/10/2012, 11:15

... Synthesis of the PNA building block backbone In the next step, the synthesis of the PNA back- bone monomer using the fluorenylmethoxycarbonyl (Fmoc) protection occurred as described by Atherton ... Sheppard.[40] Synthesis of the Fmoc-C2-glycine-tert-butyl ester The synthesis of the peptide nucleic acid back- bone requires the introduction of protecting groups a...

Ngày tải lên: 26/10/2012, 08:57