Báo cáo y học: " Endothelial Upregulation of programmed death-1 on T cells and programmed" pps

... Discussion The current study demonstrates that PD-1 on T cells and PD-L1 on monocytes are upregulated dramatically in a cohort of septic shock patients exhibiting acceler- ated lymphocyte apoptosis ... peripheral T cells, B cells and monocytes were measured using flow cytometry. Apoptosis of T cells induced by TNFa or T- cell receptor ligation in vitro and effects...

Ngày tải lên: 14/08/2014, 07:21

... in the determination of fenestration parameters, statistical analysis and assisted in the writing. CIØ carried out the isolation and characterization of the cells. GIN participated in the oxygen ... study we report that atmospheric oxygen tension has harmful effects on isolated rat LSECs during long term cultivation. These effects may be largely abrogated by incubation of the ce...

Ngày tải lên: 13/08/2014, 13:20

... and the corresponding healthy control group (P > 0.9, by Student’s t- test), between the age of the SLE patient group and the corresponding healthy control group (P > 0.9, by Student’s t- test), ... age-matched control Available online http://arthritis-research.com/content/5/2/R91 Introduction The precise role played by CD8 + T cells in the pathogene- sis and inflammation...

Ngày tải lên: 09/08/2014, 01:21

... display any of these distinct patterns of TCR-Vβ distribution. In all 13 patients, the distribution of TCR-Vβ subsets in the conventional CD4 + CD28 + T- cell population was not dramati- cally different ... patients included in these analyses. The majority of the patients were treated either with nonsteroidal anti-inflammatory drugs, with systemic or local corticosteroid treatment, w...

Ngày tải lên: 09/08/2014, 10:21

... demonstrating that the Trip10 expression is regulated epigenetically and differentially by both DNA methylation and histone modification in a cell type-specific manner. To determine Trip10 methylation ... addition, rat striatal neurons transfected with Trip10 exhibited increased cell death [9], suggesting that T rip10 is toxic to striatal neu- rons. These data demonstrate that the funct...

Ngày tải lên: 10/08/2014, 05:21

... disorders and stress. In addition, nurses who witnessed a patient suicide attempt were asked about the situation at the time of the encounter, the degree of relationship with the patient, and related ... section has roughly ten subsections. In addition, each subsection contains roughly ten questions. Thequestionnaireasawholeaskedquestionson (1) the experience of exposure to complete...

Ngày tải lên: 11/08/2014, 16:23

... Central Page 1 of 3 (page number not for citation purposes) Respiratory Research Open Access Correction Differential effects of cigarette smoke on oxidative stress and proinflammatory cytokine ... 2008 Kode et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/...

Ngày tải lên: 12/08/2014, 15:21

... by ELISA. Nuclear translocation of the transcription factor, NF-κB was assessed by immunocytochemistry and immunoblotting. Results: Cigarette smoke extract dose-dependently depleted glutathione ... amongst the five epithelial cell lines stud- ied. This potentially reflects the endogenous ability of the cells to adapt to cigarette smoke mediated injury and damage, which may in turn b...

Ngày tải lên: 12/08/2014, 16:20

... between Tregs, severity and cytokines plasma concentrations Considering the correlation between Tregs and out- come, at least in septic patients, we evaluated the rela- tion between these cells ... collected on citrated tubes. Sampling was repeated at day three, five and seven provided that the patient was still in the ICU. Flow cytometry Flow cytometry analyses were conducted on...

Ngày tải lên: 13/08/2014, 20:21

... discrepancy between the expression of TGF-β1 mRNA and protein in SFBs may be due to the fact that blot analysis with the present monoclonal antibody underestimates the total amount of protein by detecting ... osteoblasts and was based on both stimulation of gene transcription and stabilization of mRNA transcripts [37]. The rapid upregulation of mRNA after 4 h suggests a di...

Ngày tải lên: 09/08/2014, 10:20