Báo cáo y học: "Hypoxia-inducible factors and the prevention of acute organ injur" ppsx

... inhibition of PHD, under conditions when cellular oxygen demand exceeds oxygen supply, Hypoxia-inducible factors and the prevention of acute organ injury Samuel N Heyman 1 *, Seymour Rosen 2 , ... since they are rapidly hydroxylated by oxygen-dependent HIF prolyl-4- hydroxylase domain enzymes (PHD), subsequently captured by the ubiquitin ligase Von-Hippel-Lindau protein...

Ngày tải lên: 14/08/2014, 07:21

... significantly increased length of hospital stay and may have a considerable impact on morbidity and mortality [2]. Endpoints, possible risk factors for the acquisition of NP and the clinical ... risk of dying (model 2). However, these patients stay longer in the ICU. There are two possible explanations for this: firstly, there is an effect independent of whether they acq...

Ngày tải lên: 13/08/2014, 08:21

... with their pets need not represent any risk for infection with Toxoplasma gondii. Cats are the definitive host of T. gondii; they are the only animals that pass oocysts in their feces. They become ... Veterinarians are often faced with the need to explain to their clients that it is not necessary, for example, to give away one’s cat during pregnancy and that if they follow a fe...

Ngày tải lên: 03/11/2012, 11:06

... (EJP). The Daphnia pulex sequencing and portions of the analyses were performed at the DOE Joint Genome Institute under the auspices of the US Department of Energy’s Office of Science, Biological and ... Biology 2010, 11:R46 http://genomebiology.com/2010/11/4/R46 Page 6 of 13 homozygous state. Homozygosity eliminates the chance of loss by mitotic recombination and...

Ngày tải lên: 09/08/2014, 20:21

... calculation, namely stationarity and periodicity. Note that the square of the contribution of each frequency is the power of that frequency to the total spectrum, and the total power of spectral analysis (area ... from the properties of the parts, and they depend on the integrity of the whole; the systemic prop- erties vanish when the system breaks apar...

Ngày tải lên: 12/08/2014, 20:20

... multicollinearity, and estimates of adjusted R square and F statistics of the regression model [61]. Sensitivity analysis Sensitivity of the results to imputation of missing data was explored by running the ... for their efforts in gathering cost data at the country level; and Tessa Tan Torres for her input in the development of the methods used. The work repr...

Ngày tải lên: 13/08/2014, 11:22

... known about their function. Now Piwi proteins have themselves been linked to small RNAs, but little is known of the function of these piRNAs. They are perhaps the first of many new classes of RNA ... that miRNAs are not a specialty of multicellularity. The discovery of thousands of additional novel noncoding RNAs, big and small, was reported for many different groups of...

Ngày tải lên: 14/08/2014, 17:22

... possible, therefore, that reduction of airway bacter- ial load and/ or prevention of new strain acquisition in COPD patients by the use of antibiotics may reduce the frequency and severity of exacerbations. ... and assessment of data. All other authors contributed significantly to the design of the study, the collection and assessment of clinical data and de...

Ngày tải lên: 12/08/2014, 11:20

... comorbidity. Patients with psychiatric illness may not have routine general medical care and diagnosis of general medical conditions may be delayed. As the physician with the most (and often the only) ... for symptoms of cardiac pathology, such as recurrent syncope. A family history of early sudden death should be obtained and serum electrolyte imbalances should also be corre...

Ngày tải lên: 25/10/2012, 10:51

... (PLP)-dependent enzyme which catalyses the b,c- hydrolytic cleavage of the amino acids L -kynurenine (1 )and L -3-hydroxykynurenine (2)togive L -alanine (3) and either anthranilic acid (4) or 3-hydroxyanthranilic ... pathophysiology of human diseases has always been hampered by the availability of human tissue, aesthetics, and ethical considerations. The principle aim of...

Ngày tải lên: 08/03/2014, 22:20