Báo cáo y học: "Reappraising the concept of massive transfusion in trauma" doc

... Massive transfusion not only is the result of a set of clinical parameters but it also is a function of the clinical response to them. Conclusions In summary, current definitions of massive transfusion are ... care. The first aim of the study w as to assess whether a clinically relevant defini- tion of massive transfusion existed in terms of a clinical ou...

Ngày tải lên: 14/08/2014, 07:21

... 42% of children were diagnosed with AR by the age of 6 years. The prevalence of AR has increased dramatically in the past 30 years and continues to increase. Children with one component of atopy ... risk of developing a second component. 2 In 1998, the Joint Task Force on Practice Parameters in Allergy, Asthma, and Immunology defined rhinitis as ‘‘inflammation of th...

Ngày tải lên: 08/08/2014, 21:20

... obesity, gout is becoming endemic in China. Finally, symptomatic knee osteoarthritis is extremely common in China and constitutes a major public health problem there. In the present issue of Arthritis ... prevalence would often be more informative, especially since rheumatic diseases vary in prevalence by age. An additional source of Editorial Comparing the prevalence of rhe...

Ngày tải lên: 09/08/2014, 10:22

... extension of the concept of a small number of highly specific TFs that define expression domains. Recent studies, including one by Adryan and Teichmann in this issue of Genome Biology [2], put the ... expression of many genes and any given gene is typically regulated by at most a handful of transcription factors (TFs) [1]. Some studies in animals, including studies...

Ngày tải lên: 09/08/2014, 20:21

... most frequently gained protein domains in the human line- age - domains independently gained five or more times in our set - are all involved in signaling or regulatory functions; the Ankyrin repeat (gained ... protein in these species); in fruit fly the domi- nant category was extension of an e xon at the carboxyl terminus (29% of domain gains); and in zebrafish it wa...

Ngày tải lên: 09/08/2014, 20:22

... predicted body weight. Finally, the ability to interpret the fi nding that EVLW as measured by the transpulmonary thermodilution method did not correlate with EVLW assessed using the chest radiograph ... explanation for the lack of correlation between the measured EVLW and the chest radiograph fi ndings is that the heterogeneity of the patients may have reduced the...

Ngày tải lên: 13/08/2014, 21:21

... goal of identifying and treating patients early in the course of their illness is preferable to waiting until more serious signs and symptoms have developed. Certainly, at the University of ... from baseline to the study period for both groups combined. Conclusion The MET system greatly increases emergency team calling, but does not substantially affect the incidence...

Ngày tải lên: 25/10/2012, 10:39

... E a almost the same as in the case ofthenativeenzyme(Table1). Thermal inactivation of mutant and wild-type enzymes In order to investigate the effects of mutations on the stability of psychrophilic ... resulted in an enzyme with slightly lower stability. On the other hand, in the double mutant G261A /Y2 69A the additional replacement of Tyr269 by Ala restores th...

Ngày tải lên: 22/02/2014, 04:20

... hand, indicate a detectable increase in the content of secondary structure only after the disruption of the native tertiary structure of RNase A (Figs 2–4). Interestingly, the preservation of the ... probably represents fragment 21–124, as in Fig. 5A. Quantification of the proteolytic susceptibility of RNase A. To gain further insight into the changes of the p...

Ngày tải lên: 22/02/2014, 07:20

... suggested that in E301A FNR the side-chain of E139 might in uence the properties of the flavin, assuming some of the functions carried out by E301 in the wild-type enzyme [22]. In this context, ... concen- tration independent. Thus, when studying the catalytic efficiency for these mutants in the diaphorase reaction, all of them yield values very close to those of...

Ngày tải lên: 31/03/2014, 08:20