Báo cáo y học: "Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats" potx
Báo cáo y học: "Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats" potx
... Landsberger et al.: Inhibition of lectin-like oxidized low-density lipoprotein receptor-1 reduces leukocyte adhesion within the intestinal microcirculation in experimental endotoxemia in rats. Critical ... 14:R223 http://ccforum.com/content/14/6/R223 Page 8 of 8 RESEARC H Open Access Inhibition of lectin-like oxidized low-density lipoprotein rece...
Ngày tải lên: 14/08/2014, 07:21
Tài liệu Báo cáo Y học: Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation ppt
... NAMI-A-mediated inhibition of ERK1/2 phosphorylation may be lying upstream of ERK1/2. Using a serine/threonine kinase SPA assay kit, the capability of NAMI-A to affect the ERK1/2 phosphoryla- tion activity ... maintenance of tumor cell growth [3]. The finding that the ERK signaling pathway is involved in tumor cell migration and invasion [4,5], as well as in tubular formati...
Ngày tải lên: 21/02/2014, 01:21
Tài liệu Báo cáo Y học: Inhibition of nuclear pre-mRNA splicing by antibiotics in vitro pot
... with the binding o f the functional sub strate. Type-II binding sites are the central metal ion-binding pock- ets i n the catalytic cores of ribozymes. In type-II binding sites the aminoglycosides ... [31]. RESULTS Erythromycin, Cl-tetracycline and streptomycin inhibit nuclear splicing in vitro The effects of eight different antibiotics (the aminoglycoside, kanamycin, th...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo Y học: Inhibition of hyaluronan synthesis in Streptococcus equi FM100 by 4-methylumbelliferone doc
... level of the has operon containing the hyaluronan synthase gene or the protein level of hyaluronan synthase. Solubilization of the enzyme from membranes of MU-treated cells and addition of the ... MU-meta- bolites in the inhibition of HA synthesis by MU in FM100 cells. These above results indicate that something required for a fully functional HA synthesis system i...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Inhibition of the SERCA Ca21 pumps by curcumin Curcumin putatively stabilizes the interaction between the nucleotide-binding and phosphorylation domains in the absence of ATP pot
... into contact in the absence of ATP, curcumin is then able to bind to the ATPase (possibly at the hinge region) locking the two domains together and therefore precluding ATP binding (i.e. inhibiting ... possibly increased. In order to further assess the possibility of curcumin affecting the interaction of ATP binding to the ATPase, this was directly measured using [ 32...
Ngày tải lên: 08/03/2014, 23:20
Báo cáo Y học: Inhibition of glycosyl-phosphatidylinositol biosynthesis in Plasmodium falciparum by C-2 substituted mannose analogues pot
... glucosamine into GPtdIns may point to an inhibition of GPtdIns biosynthesis by a mechanism which is different from the ones observed in other systems, that is, the incorporation of mannosamine into the ... study glycosylphosphatidylinositol (GPtdIns) biosynthesis and GPtdIns protein anchoring in protozoal and mammalian systems. The effects of these analogues on GPtdIns biosy...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo Y học: Inhibition of SERCA Ca2+ pumps by 2-aminoethoxydiphenyl borate (2-APB) 2-APB reduces both Ca2+ binding and phosphoryl transfer from ATP, by interfering with the pathway leading to the Ca2+-binding sites ppt
... indicates a crucial role for the hydroxyl group of this tyrosine residue in the binding of 2-APB to the enzyme. DISCUSSION 2-APB has been used extensively recently to investigate the effects ... described in this study, 2-APB reduces the affinity for Ca 2+ binding to the ATPase in a competitive manner and inhibits phosphoryl transfer without affecting nucleotide binding...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo y học: "Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis" potx
... pathogenesis of RA. The principal plasma inhibitor of thrombin is antithrombin, a single-chain 51 kDa glycoprotein that is synthesized in liver. The inhibitory activity of antithrombin on thrombin is ... wavelength of 405 nm. Hence, the inhibitory ability of antithrombin on thrombin was inversely proportional to the residual thrombin activity. This assay method is usually...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: "Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice" docx
... purposes) [35]. Internalization of CII was also undetectable in the pres- ence of amiloride (Figure 2b), suggesting the involvement of macropinocytosis rather than phagocytosis in the uptake of CII [28]. In ... examined, presumably because of the low probability of the plane section coinciding with the longitudinal axis of the CII fibrils. Electron microscopy...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts" pdf
... in the writing of the manuscript. SB and AN participated in the design of the study and the writ- ing of the manuscript. EK participated in the design of the study, the analysis of data and the ... the reduced viability in the presence of statins. Geranylgeranylated proteins are redistributed to the cytoplasm in the presence of statins To e...
Ngày tải lên: 09/08/2014, 08:22